Vol. 4 February 23–March 2, 1985, St. Christoph, Arlberg, Austria

Published by De Gruyter 1985

Vol. 4 February 23–March 2, 1985, St. Christoph, Arlberg, Austria

Edited by: Helmut Wachter , H. Ch. Curtius and W. Pfleiderer

Part of the multi-volume work Biochemical and Clinical Aspects of Pteridines. Cancer - Immunology - Metabolic Diseases

https://doi.org/10.1515/9783110860566

Contents

Frontmatter Publicly Available Download PDF	I
PREFACE Publicly Available Download PDF	V
LIST OF PARTICIPANTS Publicly Available Download PDF	VII
CONTENTS Publicly Available Download PDF	XIII
1. CHEMISTRY AND ANALYSIS OF PTERIDINES
ELECTROLYSIS OF PTERIDINES Wolfgang Pfleiderer and Raphael Gottlieb Requires Authentication Unlicensed Licensed Download PDF	3
NITRITE OXIDATION OF TETRAHYDROPTERINS S.J.R. Heales, J.A. Blair, A.E. Guest and A.E. Pheasant Requires Authentication Unlicensed Licensed Download PDF	17
ACYLATION OF TETRAHYDROPTERINS Ronan John Lockhart and Wolfgang Pfleiderer Requires Authentication Unlicensed Licensed Download PDF	27
SYNTHESIS AND PROPERTIES OF 5,6-DIHYDROPTERIDINES Rainer Soyka and Wolfgang Pfleiderer Requires Authentication Unlicensed Licensed Download PDF	33
SYNTHESIS AND PROPERTIES OF NEW TETRAHYDROPTERIDINES Hermann Traub and Wolfgang Pfleiderer Requires Authentication Unlicensed Licensed Download PDF	45
INTER- AND INTRAMOLECULAR REDOX-REACTIONS BY 5,6- RESP. 7,8-DIHYDROPTERINES; DO THESE COMPOUNDS BEHAVE AS REDOX COFACTORS DURING THE BIOSYNTHESIS OF 5,6,7,8-TETRAHYDRO-L-BIOPTERIN ? Max Viscontini Requires Authentication Unlicensed Licensed Download PDF	57
DETERMINATION OF NEOPTERIN AND REDUCED NEOPTERINS BY RADIOIMMUNOASSAY H. Rokos, G. Bienhaus, A. Gadow and K. Rokos Requires Authentication Unlicensed Licensed Download PDF	73
THE DETERMINATION OF PTERINS, BIOGENIC AMINE METABOLITES, AND AROMATIC AMINO ACIDS IN CEREBROSPINAL FLUID USING ISOCRATIC REVERSE PHASE LIQUID CHROMATOGRAPHY WITH IN SERIES DUAL CELL COULOMETRIC ELECTROCHEMICAL AND FLUORESCENCE DETECTION:- USE IN THE STUDY OF INBORN ERRORS OF DIHYDROPTERIDINE REDUCTASE AND 5,lO-METHYLENETETRAHYDROFOLATE REDUCTASE K. Hyland, I. Smith, D. W. Howells, P. T. Clayton and J. V. Leonard Requires Authentication Unlicensed Licensed Download PDF	85
2. BIOCHEMISTRY AND METABOLISM OF PTERIDINES
TETRAHYDROBIOPTERIN METABOLISM IN THE CENTRAL NERVOUS SYSTEM John A. Blair Requires Authentication Unlicensed Licensed Download PDF	103
ENZYMATIC FORMATION OF H₄-BIOPTERIN IN DROSOPHILA MELANOGASTER G.M. Brown, A.C. Switchenko and J.P. Primus Requires Authentication Unlicensed Licensed Download PDF	119
TETRAHYDROBIOPTERIN BIOSYNTHESIS. STUDIES ON THE REACTION OF DIHYDRONEOPTERIN TRIPHOSPHATE IN THE PRESENCE OF PHOSPHATE-ELIMINATING ENZYME FROM HUMAN LIVER H.-Ch. Curtius, W. Leimbacher, A. Niederwieser and Sandro Ghisla Requires Authentication Unlicensed Licensed Download PDF	133
BIOSYNTHESIS OF TETRAHYDROBIOPTERIN: INCORPORATION OF LABEL FROM REDUCED PYRIDINE NUCLEOTIDE DURING FORMATION FROM DIHYDRONEOPTERIN TRIPHOSPHATE Sandro Ghisla, Hans-Christoph Curtius, Dorothee Heintel, Thomas Küster, Walter Leimbacher and Alois Niederwieser Requires Authentication Unlicensed Licensed Download PDF	143
TETRAHYDROBIOPTERIN BIOSYNTHESIS IN MAN Dorothee Heintel, Walter Leimbacher, Udo Redweik, Nenad Blau, Alois Niederwieser, Hans-Christoph Curtius and Sandro Ghisla Requires Authentication Unlicensed Licensed Download PDF	151
PHOSPHORYLATION OF UNPROTECTED D-NEOPTERIN B. Zagalak, F. Neuheiser and H.-Ch. Curtius Requires Authentication Unlicensed Licensed Download PDF	159
MEASUREMENT OF PHOSPHATE-ELIMINATING ENZYME (PEE) ACTIVITY IN LIVER BIOPSIES A. Niederwieser, W. Leimbacher and H.-Ch. Curtius Requires Authentication Unlicensed Licensed Download PDF	169
INHIBITION OF THE TETRAHYDROPTERIN PATHWAY FOR BIOPTERIN COFACTOR BIOSYNTHESIS BY N-ACETYLSEROTONIN IN CELL CULTURES AND IN ENZYME PREPARATIONS AND STUDIES ON THE MECHANISM OF TETRAHYDROPTERIN FORMATION Gary K. Smith, David S. Duch and Charles A. Nichol Requires Authentication Unlicensed Licensed Download PDF	175
ACTH STIMULATION OF TETRAHYDROBIOPTERIN BIOSYNTHESIS AND STEROIDOGENESIS IN ADRENAL CORTICAL TUMOR CELLS IN CULTURE David S. Duch, Jeffrey H. Woolf, Mark P. Edelstein, O. Humberto Viveros, Martha M. Abou-Donia and Charles A. Nichol Requires Authentication Unlicensed Licensed Download PDF	195
ENDOCRINE AND METABOLIC REGULATION OF GTP-CYCLOHYDROLASE ACTIVITY AND TETRAHYDROBIOPTERIN LEVELS IN RAT LIVER Martha M. Abou-Donia, Alejandro J. Daniels, Emanuel Diliberto, Charles A. Nichol and O. Humberto Viveros Requires Authentication Unlicensed Licensed Download PDF	209
TETRAHYDROBIOPTERIN SYNTHESIS AND THE ROLE OF THE COFACTOR IN THE REGULATION OF TYROSINE HYDROXYLATION IN ADRENOMEDULLARY CHROMAFFIN CELLS Martha M. Abou-Donia, Thomas P. Zimmerman, Charles A. Nichol and O. Humberto Viveros Requires Authentication Unlicensed Licensed Download PDF	221
BIOPTERIN METABOLISM IN HEPATOMA CELLS Jean-Louis Dhondt, Richard G.H. Cotton and Kerry Fowler Requires Authentication Unlicensed Licensed Download PDF	237
HIGH BIOPTERIN CONCENTRATION IN NUCLEAR FRACTIONS OF REGIONAL RAT-BRAIN PREPARATIONS S. Knapp and M. Merwin Requires Authentication Unlicensed Licensed Download PDF	245
3. TETRAHYDROBIOPTERIN DEFICIENCIES, DIAGNOSIS AND THERAPY
TRANSIENT NEONATAL HYPERPHENYLALANINEMIA DUE TO DEFECTIVE SYNTHESIS OF 7,8-DIHYDROBIOPTERIN Y. Okano, H. Shintuku, Y. Sawada, G. Isshiki, Y. Hase, T. Tsuruhara, T. Oura, S. Takahashi and Y. Kodama Requires Authentication Unlicensed Licensed Download PDF	259
TETRAHYDROBIOPTERIN ANALOGUES AND THEIR ABILITY TO ENTER THE RAT STRIATUM AFTER PERIPHERAL ADMINISTRATION Robert A. Levine, Gerd Peter Zoephel, Alois Niederwieser, Hans-Christoph Curtius, Herman Traub and Wolfgang Pfleiderer Requires Authentication Unlicensed Licensed Download PDF	269
4. PTERIDINES IN IMMUNOLOGY
IMMUNE RESPONSE- ASSOCIATED NEOPTERIN RELEASE: AN OVERVIEW Christoph Huber and Jacob Troppmair Requires Authentication Unlicensed Licensed Download PDF	279
NEOPTERIN ESTIMATION an in vivo test measuring the cell mediated immune status Dietmar Fuch, Arno Hausen, Hermann Lutz, Gilbert Reibnegger, Ernst R. Werner and Helmut Wächter Requires Authentication Unlicensed Licensed Download PDF	287
NEOPTERIN IN SERUM OF MAMMALS? H. Rokos, G. Bienhaus and R. Kunze Requires Authentication Unlicensed Licensed Download PDF	313
The Relations of HTLV-III antibodies to Neopterin and Beta-2- Microglobulin in the Serum of Patients with AIDS or Persons at Risk F.-D. Goebel, V. Erfle, H. Piechowiak, P. Hien, H. Schloz and R. Hehlmann Requires Authentication Unlicensed Licensed Download PDF	319
INCREASE IN SERUM NEOPTERIN LEVELS IN PATIENTS RECEIVING RECOMBINANT INTE RLE UK IN-2 AND RECOMBINANT INTERFERON CC A P. Kern and M. Dietrich Requires Authentication Unlicensed Licensed Download PDF	335
CLINICAL RESOLVEMENT OF MALARIA INFECTION PARALLELS DECREASE OF HIGHLY ELEVATED SERUM NEOPTERIN LEVEL P. Kern, R.D. Horstmann and M. Dietrich Requires Authentication Unlicensed Licensed Download PDF	341
ACCUMULATION AND RELEASE OF PTERIDINES DURING STIMULATION OF HUMAN PERIPHERAL BLOOD MONONUCLEAR CELLS: PARTICIPATION IN THE CONTROL OF ANTIGEN INDUCED T-CELL EXPANSION I. Ziegler Requires Authentication Unlicensed Licensed Download PDF	347
INTRACELLULAR CHANGES IN PTERIN RELEASING PERIPHERAL BLOOD MONONUCLEAR CELLS AFTER STIMULATION WITH INTERFERON-GAMMA J. Troppmair, A. Lang, Ch. Huber, G. Schoedon, A. Niederwieser and G. Adolf Requires Authentication Unlicensed Licensed Download PDF	363
METABOLISM OF PTERINS IN HUMAN PERIPHERAL BLOOD MONONUCLEAR Gabriele Schoedon, Alois Niederwieser, Jakob Troppmair and Christoph Huber Requires Authentication Unlicensed Licensed Download PDF	369
URINARY NEOPTERIN EXCRETION IN THE FOLLOW UP OF BONE MARROW TRANSPLANT RECIPIENTS D. Niederwieser, Ch. Huber, J. Troppmair, A. Gratwohl, A. Würsch, B. Speck, R. Margreiter, G. Adolf, D. Fuchs, A. Hausen, G. Reibnegger and H. Wächter Requires Authentication Unlicensed Licensed Download PDF	379
PTERIDINES IN BONE MARROW TRANSPLANTATION: THE PROBLEM OF PHARMACOLOGICAL. INTERACTIONS M. Fink, I. Ziegler and H. Rokos Requires Authentication Unlicensed Licensed Download PDF	387
SERUM NEOPTERIN DETERMINATION IN BONE MARROW TRANSPLANTATION IN CHILDHOOD H.R.M. Lang, W. Schmiedmeier and Huber J.F.K. Requires Authentication Unlicensed Licensed Download PDF	403
RADIOIMMUNOLOGICAL DETERMINATION OF SERUM NEOPTERIN IN PATIENTS FOLLOWING BONE MARROW TRANSPLANTATION - FIRST RESULTS P. Kalhs, M. Fischer, R. Dudczak, W. Hinterberger, K. Lechner, I. Schwarzinger, H. Frischauf, E. Deutsch and B. Volc-Platzer Requires Authentication Unlicensed Licensed Download PDF	411
PTERIDINES IN URINE AND SERUM IN KIDNEY ALLOGRAFT RECIPIENTS J.L. Dhondt, J.M. Hayte and C. Noël Requires Authentication Unlicensed Licensed Download PDF	419
RELATION OF NEOPTERIN TO INTERFERON GAMMA SERUM LEVELS IN PATIENTS WITH KIDNEY TRANSPLANTS W. Woloszczuk, J. Kovarik, M. Schwarz, E. Pohanka and G. Mayer Requires Authentication Unlicensed Licensed Download PDF	429
SERUM NEOPTERIN IN PATIENTS WITH KIDNEY ALLOGRAFTS: CLINICAL IMPLICATIONS M. Schwarz, E. Pohanka, G. Mayer, J. Kovarik and W. Woloszczuk Requires Authentication Unlicensed Licensed Download PDF	441
URINARY NEOPTERIN IN ACUTE AND CHRONIC LIVER DISEASES A.M.G. Farci, R. Laconi, F. Cabras, A. Loviselli, G. Cappai, A. Balestrieri, V.L. Garau, M. Tocco and D. Casula Requires Authentication Unlicensed Licensed Download PDF	453
URINARY NEOPTERIN EXCRETION AS AN ACTIVITY PARAMETER IN CROHN'S DISEASE Ch. Prior, G. Judmaier, D. Fuchs, A. Hausen, G. Reibnegger, E. R. Werner, H. Wächter, R. Bollbach and H. W. Rotthauwe Requires Authentication Unlicensed Licensed Download PDF	461
INTERFERON-GAMMA-INDUCED IN VITRO-EXCRETION OF NEOPTERIN AND 3-HYDROXYANTHRANILIC ACID BY HUMAN MACROPHAGES Ernst R. Werner, Dietmar Fuchs, Arno Hausen, Hermann Lutz, Gilbert Reibnegger, Helmut Wächter, Christoph Huber and Jakob Troppmair Requires Authentication Unlicensed Licensed Download PDF	473
5. PTERIDINES IN CANCER AND OTHER DISEASES
INTERPRETATION OF THE VARIABLE NEOPTERIN EXCRETION IN PATIENTS WITH DIFFERENT TUMOR TYPES - A HYPOTHESIS Arno Hausen, Dietmar Fuchs, Hermann Lutz, Gilbert Reibnegger, Ernst R. Werner and Helmut Wachter Requires Authentication Unlicensed Licensed Download PDF	487
URINARY NEOPTERIN IN CHILDREN WITH MALIGNANT NEOPLASM Haruo Shintaku, Kazumi Yamato, Yoshitomo Sawada, Yusuke Miyata, Gen Isshiki, Yutaka Hase, Tsuneo Tsuruhara, Toshiaki Oura, Mitsuru Tanaka and Shiro Nakamura Requires Authentication Unlicensed Licensed Download PDF	501
THE CLINICAL RELEVANCE OF THE NEOPTERIN-DETERMINATION IN PATIENTS WITH CERVICAL AND OVARIAN CANCER Heinz Hetzel, Alfred Bichler, Lothar C. Fuith, Dietmar Fuchs, Arno Hausen, Hernann Lutz, Gilbert Reibnegger, Ernst R. Werner and Helmut Wächter Requires Authentication Unlicensed Licensed Download PDF	515
DETERMINATION OF SERUM NEOPTERIN IN PATIENTS WITH ACUTE LEUKEMIA AND MALIGNANT LYMPHOMAS H.R.M. Lang, W. Linkesch and J.F.K. Huber Requires Authentication Unlicensed Licensed Download PDF	525
NEOPTERIN - A MARKER OF THE CELLULAR IMMUNE RESPONSE IN PATIENTS WITH LUNG CANCER F. Conrad, G.M. Salzer, D. Fuchs, A. Hausen, G. Reibnegger and H. Wachter Requires Authentication Unlicensed Licensed Download PDF	535
Neopterin levels in different human tumors under treatment with antitumoral peptides (Factor AF2), course, response rate, prognosis W. Voelter, B. Ebner, H. Bauer, H. Róhrer, H. Porcher and Th. Stiefel Requires Authentication Unlicensed Licensed Download PDF	545
PTERIDINES IN PLASMA AND IN BLOOD CELLS FROM LEUKAEMIA PATIENTS B. Andondonskaja-Renz and H.-J. Zeitler Requires Authentication Unlicensed Licensed Download PDF	559
PTERIDINES FROM BONE MARROW AND BODY FLUIDS FROM HEALTHY DONORS AND FROM DIFFERENT PATIENTS H.-J. Zeitler and B. Andondonskaja-Renz Requires Authentication Unlicensed Licensed Download PDF	577
PTERIDINE LEVELS IN PATIENTS WITH AIDS (ACQUIRED IMMUNODEFICIENCY SYNDROME) AND WITH KAPOSI'S SARCOMA H.-J. Zeitler and B. Andondonskaja-Renz Requires Authentication Unlicensed Licensed Download PDF	593
Comparative Studies on Urinary Neopterin Excretion and other Laboratory Parameters G. Reibnegger, D. Fuchs, A. Hausen, H. Lutz, E.R. Werner and H. Wächter Requires Authentication Unlicensed Licensed Download PDF	607
6. MISCELLANEOUS
EFFECT OF PTERIDINES ON HYDROXY-INDOLE-O-METHYLTRANSFERASE HIOMT) G. Cremer-Bartels Requires Authentication Unlicensed Licensed Download PDF	621
PTERIDINE VALUES IN CEREBROSPINAL FLUID IN SICK CHILDREN Yoshitomo Sawada, Haruo Shintaku, Gen Isshiki, Yutaka Hase, Tsuneo Tsuruhara and Toshiaki Oura Requires Authentication Unlicensed Licensed Download PDF	635
EXOGENOUS FACTORS INFLUENCING THE EXCRCETION OF NEOPTERIN H.J. Wildgrube, H. Stockhausen and W. Stockhausen Requires Authentication Unlicensed Licensed Download PDF	643
NEONATAL MEGALOBLASTIC ANEMIA CAUSED BY AN INHERITED DEFECT IN THE METHIONINE SYNTHETASE REACTION IN VIVO Bernard A. Cooper and David Rosenblatt Requires Authentication Unlicensed Licensed Download PDF	653
AUTHOR INDEX Requires Authentication Unlicensed Licensed Download PDF	661
SUBJECT INDEX Requires Authentication Unlicensed Licensed Download PDF	663
Backmatter Requires Authentication Unlicensed Licensed Download PDF	687

Language: English
Publisher: De Gruyter
Edition: Reprint 2019
Pages
- Front matter: 22
- Main content: 686
Illustrations
- Other: Num. figs., tabs
Keywords: Krebs; Pteridine; Immunologie; Stoffwechselkrankheit

eBook

Published: October 8, 2019
ISBN: 9783110860566

Hardcover

Published: October 1, 1985
ISBN: 9783110101829