Stem Cells - From Drug to Drug Discovery

Published by De Gruyter 2017

Stem Cells - From Drug to Drug Discovery

Edited by: Khawaja Husnain Haider
With contributions by: Cao Tong , Sriram Gopu , Asmat Saleem , Irfan Khan , Nadia Naeem , Anwar Ali , Riazuddin Sheikh , Moazzam Nazeer Tarar , Azra Mehmood , Noreen Latief , Mansour Alsharida , Elmuataz Elmansi Abdalla , Salman Afroze , Kai Zhu , Changfa Guo , Seyyed Mohyeddin Ziaee , Parisa Tabeshmehr and Ye Lei

https://doi.org/10.1515/9783110493764

Overview
Contents

About this book

Stem cell based therapy is a 21^st century approach of therapeutic intervention which epitomizes a shift from conventional symptomatic treatment strategy to addressing the root cause of the disease process. This is especially a hope for the patients suffering from diseases such as Alzheimer, diabetes, myocardial infarction and other diseases which have always been considered as incurable. Moreover, stem cells provide excellent in vitro disease models for drug development. This book is a compilation of the bench experience of experts from various research labs involved in the cutting edge area of research, describing the use of stem cells both as part of the combinatorial therapeutic intervention approach and as tools (disease model) during drug development.

Covers a wide range of topics from adult stem cells to pluripotent stem cells
Describes stem cells as drugs (combinatorial therapeutic interventions) and as tools (disease model)
Contributes to the exciting field of regenerative medicine

Author / Editor information

Khawaja Husnain Haider, Kingdom of Saudi Arabia.

Topics

Frontmatter Publicly Available Download PDF	i
Preface Requires Authentication Unlicensed Licensed Download PDF	v
Contents Publicly Available Download PDF	vii
Contributing authors Requires Authentication Unlicensed Licensed Download PDF	xiii
List of abbreviations Requires Authentication Unlicensed Licensed Download PDF	xv
1. Human pluripotent stem-cell-derived vascular cells: in vitro model for angiogenesis and drug discovery Sriram Gopu and Cao Tong Requires Authentication Unlicensed Licensed Download PDF	1
2. Role of small molecules in the cardiac differentiation of mesenchymal stem cells Irfan Khan, Nadia Naeem, Anwar Ali and Asmat Salim Requires Authentication Unlicensed Licensed Download PDF	35
3. MicroRNAs as modulators of endothelial differentiation of stem cells: role in vascular regenerative medicine Dursun Gündüz and Muhammad Aslam Requires Authentication Unlicensed Licensed Download PDF	63
4. Cells for the repair of damaged skin and cartilage Sheikh Riazuddin, Azra Mehmood, Noreen Latief and Moazzam Nazeer Tarar Requires Authentication Unlicensed Licensed Download PDF	85
5. The skeletal muscle stem cells: biology and use in regenerative medicine Mansour Saleh Alsharidah, Khawaja Husnain Haider, Elmuataz Elmansi Abdalla and Salman Afroze Azmi Mohammed Requires Authentication Unlicensed Licensed Download PDF	111
6. Nanoparticle-based genetic engineering of mesenchymal stem cells Changfa Guo, Kai Zhu and Khawaja Husnain Haider Requires Authentication Unlicensed Licensed Download PDF	129
7. Neural stem cells in regenerative medicine Seyed Mojtaba Hosseini, Seyyed Mohyeddin Ziaee and Parisa Tabeshmehr Requires Authentication Unlicensed Licensed Download PDF	148
8. “Paracrining” the heart with stem cells Ye Lei and Khawaja Husnain Haider Requires Authentication Unlicensed Licensed Download PDF	176
Index Requires Authentication Unlicensed Licensed Download PDF	204

(Deutsch)

Language: English
Publisher: De Gruyter
Audience: Molecular biologists and medical researchers in the field of regenerative medicine
Pages
- Front matter: 18
- Main content: 214
Illustrations
- Coloured Illustrations: 20
Keywords: Regenerative Medicine; Cell therapy; Cell differentiation; Pharmaceutical research

eBook

Published: March 20, 2017
ISBN: 9783110493764

Hardcover

Published: March 20, 2017
ISBN: 9783110496284