Chemistry of Penicillin

Published by Princeton University Press 1949

Chemistry of Penicillin

Edited by: Hans T. Clarke

Volume 2167 in the series Princeton Legacy Library

https://doi.org/10.1515/9781400874910

Overview
Contents

About this book

This book makes available, for interested scientists to procure, absorb, and evaluate, the vast body of information on the research and results of the work on the chemistry of penicillin done in England and the United States during the war. The National Academy of Sciences arranged for the preparation of this summary, Dr. H. T. Clarke and Dr. J. R. Johnson representing the United States on the editorial board, and Sir Robert Robinson representing Britain. The body of the work was prepared by more than 60 outstanding biochemists and biophysicists, who describe the phases of research to which they contributed the most. The work of 23 academic, medical, industrial, and government laboratories is reported.

Originally published in 1949.

The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.

Topics

Frontmatter Publicly Available Download PDF	i
Preface Requires Authentication Unlicensed Licensed Download PDF	v
Contents Publicly Available Download PDF	ix
I. Brief History of the Chemical Study of Penicillin Hans T. Clarke, John R. Johnson and Robert Robinson Requires Authentication Unlicensed Licensed Download PDF	1
II. The Earlier Investigations relating to 2-Pentenylpenicillin E. P. Abraham, W. Baker, W. R. Boon, C. T. Calam, H. C. Carlington, E. Chain, H. W. Florey, G. G. Freeman, R. Robinson and A. G. Sanders Requires Authentication Unlicensed Licensed Download PDF	10
III. The Chemistry of n-Amylpenicillin up to December 1943 A. H. Cook and I. M. Heilbron Requires Authentication Unlicensed Licensed Download PDF	38
IV. Status of the Research on the Structure of Benzylpenicillin in December 1943 Robert L. Peck and Karl Folkers Requires Authentication Unlicensed Licensed Download PDF	52
V. Isolation and Characterization of the Various Penicillins O. Wintersteiner, W. R. Boon, H. C. Carrington, D. W. Maccorquodale, F. H. Stodola, J. L. Wachtel, R. D. Coghill, W. C. Risser, J. E. Philip and O. Touster Requires Authentication Unlicensed Licensed Download PDF	76
VI. Penillic Acids and Penillamines A. H. Cook Requires Authentication Unlicensed Licensed Download PDF	106
VII. Review of Certain Investigations on the Structure of Benzylpenicillin during 1944-1945 Robert L. Peck and Karl Folkers Requires Authentication Unlicensed Licensed Download PDF	144
VIII. Some Inactivation and Degradation Reactions not included in Chapters IV and VII O. Wintersteiner, Η. E. Stavely, J. D. Dutcher and M. A. Spielman Requires Authentication Unlicensed Licensed Download PDF	207
IX. Desthiobenzylpenicillin and Other Hydrogenolysis Products of Benzylpenicillin Edward Kaczka and Karl Folkers Requires Authentication Unlicensed Licensed Download PDF	243
X. The Thiocyanate Derivative of Benzylpenicillin Methyl Ester Vincent du Vigneaud and Donald B. Melville Requires Authentication Unlicensed Licensed Download PDF	269
XI. The X-Ray Crystallographic Investigation of the Structure of Penicillin D. Crowfoot, C. W. Bunn, B. W. Rogers-Low and A. Turner-Jones Requires Authentication Unlicensed Licensed Download PDF	310
XII. Identification and Crystallography of Penicillins and Related Compounds by X-Ray Diffraction Methods G. L. Clark, W. I. Kaye, K. J. Pipenberg and N. C. Schieltz Requires Authentication Unlicensed Licensed Download PDF	367
XIII. Infrared Spectroscopic Studies on the Structure of Penicillin H. W. Thompson, R. R. Brattain, Η. M. Randall and R. S. Rasmussen Requires Authentication Unlicensed Licensed Download PDF	382
XIV. Other Physical Methods R. B. Woodward, A. Neuberger and N. R. Trenner Requires Authentication Unlicensed Licensed Download PDF	415
XV. The Constitution of Penicillins J. R. Johnson, R. B. Woodward and R. Robinson Requires Authentication Unlicensed Licensed Download PDF	440
XVI. Penicillamine, Its Analogs and Homologs Harry M. Crooks Requires Authentication Unlicensed Licensed Download PDF	455
XVII. Penilloaldehydes and Penaldic Acids Ellis V. Brown Requires Authentication Unlicensed Licensed Download PDF	473
XVIII. The Penilloic and Penicilloic Acids and Their Derivatives and Analogs Ralph Mozingo and Karl Folkers Requires Authentication Unlicensed Licensed Download PDF	535
XIX. Biosynthesis of Penicillins Otto K. Behrens Requires Authentication Unlicensed Licensed Download PDF	657
XX. Chemical Modifications of Natural Penicillins R. D. Coghill, F. H. Stodola and J. L. Wachtel Requires Authentication Unlicensed Licensed Download PDF	680
XXI. Oxazoles and Oxazolones J. W. Cornforth Requires Authentication Unlicensed Licensed Download PDF	688
XXII. Attempted Syntheses of Penicillins W. E. Bachmann and M. W. Cronyn Requires Authentication Unlicensed Licensed Download PDF	849
XXIII. The Condensation of Oxazolones and D-Penicillamine and the Resultant Antibiotic Activity V. du Vigneaud, J. L. Wood and Μ. E. Wright Requires Authentication Unlicensed Licensed Download PDF	892
XXIV. Methyl Benzylpseudopenicillinate J. H. Hunter, J. W. Hinman and Η. E. Carter Requires Authentication Unlicensed Licensed Download PDF	909
XXV. Thiazolidines A. H. Cook and I. M. Heilbron Requires Authentication Unlicensed Licensed Download PDF	921
XXVI. The Chemistry of β-Lactams S. A. Ballard, D. S. Melstrom and C. W. Smith Requires Authentication Unlicensed Licensed Download PDF	973
XXVII. The γ-Lactam of Benzylhomopenicilloic Acid and Related Compounds Vincent du Vigneaud and Frederick H. Carpenter Requires Authentication Unlicensed Licensed Download PDF	1004
XXVIII. Synthetic Benzylpenicillin Vincent du Vigneaud, Frederick H. Carpenter, Robert W. Holley, Arthur H. Livermore and Julian R. Rachele Requires Authentication Unlicensed Licensed Download PDF	1018
XXIX. Assay of Penicillins John V. Scudi and Η. B. Woodruff Requires Authentication Unlicensed Licensed Download PDF	1025
XXX. Appendix Requires Authentication Unlicensed Licensed Download PDF	1043
SUBJECT INDEX Requires Authentication Unlicensed Licensed Download PDF	1069

Language: English
Publisher: Princeton University Press
Copyright year: 1949
Audience: Professional and scholarly;College/higher education;
Pages
- Main content: 1120

eBook

Published: December 8, 2015
ISBN: 9781400874910