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Challenges and Opportunities of mRNA Vaccines Against SARS-CoV-2

A Multidisciplinary Perspective

  • Book
  • © 2023

Overview

Authors:
  1. Siguna Mueller

    1. Kaernten, Austria

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  • Analyzes the the risks and benefits of mass vaccination with mRNA vaccines
  • Covers the most recent scientific data on Covid-19 mRNA vaccines
  • Offers a broad multidisciplinary look at mRNA vaccines

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Table of contents (13 chapters)

  1. Front Matter

    Pages i-xxxii
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  2. Introduction

    • Siguna Mueller
    Pages 1-9

  3. Scientific Underpinnings, Early Expectations, and Emerging Challenges from the Global Inoculation Experience

    1. Front Matter

      Pages 11-11
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    2. Appraisal of Some of the Key Postulates Underlying mRNA Vaccines

      • Siguna Mueller
      Pages 13-40

    3. Relevance for mRNA Vaccine Safety

      • Siguna Mueller
      Pages 41-85

    4. From Challenges to Opportunities and Open Questions

      • Siguna Mueller
      Pages 87-130

    5. The Challenge of Evaluating Vaccine Safety and Effectiveness

      • Siguna Mueller
      Pages 131-162

    6. Safeguarding Against the Analog of Antimicrobial-Resistance Development

      • Siguna Mueller
      Pages 163-176

    7. Scales, Pseudoscales, the Human Factor, and a Way Forward

      • Siguna Mueller
      Pages 177-224

  5. The Omicron Variants

    1. Front Matter

      Pages 365-365
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    2. Omicron

      • Siguna Mueller
      Pages 367-413

    3. Conclusion

      • Siguna Mueller
      Pages 415-439
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Keywords

About this book

This book offers an analytical look at the much debated risks and benefits of the newly developed COVID-19 mRNA-vaccines. As such, it is one of the first books to give a comprehensive overview of mRNA vaccines against COVID-19 and the only one that addresses this topic from a broad multidisciplinary background. It brings together insights from various underlying disciplines on the challenges of developing and evaluating the most suitable vaccines for mass vaccination programs enrolled throughout the world - focusing on safety and efficacy.



This book should not be missing on the shelf of any biomedical researcher, epidemiologist, public health professional or clinical researcher interested in SARS-CoV2 or virology and vaccine development in general. 


Authors and Affiliations

  • Kaernten, Austria

    Siguna Mueller

About the author

Siguna Mueller spent the first 20 years of her academic career in mathematics (M.S. in Mathematics and Statistics and Ph.D. in Mathematics, University of Klagenfurt, Austria, both summa cum laude). She was among the first women in Austria to receive the Habilitation in Discrete Mathematics and Cryptography (2002). The following 15 years she spent as a Research Associate at the Centre for Information Security and Cryptography Research, University of Calgary, and as an Assistant Professor at the University of Wyoming. A lifelong passion for biology and medicine eventually triggered her decision to radically expand her field of expertise. Consequently, she earned her second Ph.D. (Biomedical Sciences) in 2014 at the University of Wyoming (with a GPA of 4.0). Since then she has been utilizing her experience in the theoretical fields to help advance a broader appreciation and comprehension of phenomena and challenges arising in the biological and life science domains. For almost ten years, she has been warning of new Biosafety and Public Health dangers, but for years was ignored. Only recently, her concerns about new safety/security challenges in synthetic biology have been supported by others, and she has become one of the leaders in the new field of cyberbiosecurity. Her interests and curiosities are not limited to the above-mentioned disciplines as she finds great excitement in physics, theology, philosophy, ethics, spirituality, and the complexity and fascination of nature altogether. As such, it has been natural for her, employing her multi-disciplinary experience, to appraise the new Covid-19 vaccines, through rigorous, balanced, and scientific logic.




Bibliographic Information

  • Book Title: Challenges and Opportunities of mRNA Vaccines Against SARS-CoV-2

  • Book Subtitle: A Multidisciplinary Perspective

  • Authors: Siguna Mueller

  • DOI: https://doi.org/10.1007/978-3-031-18903-6

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2023

  • Hardcover ISBN: 978-3-031-18902-9Published: 06 January 2023

  • Softcover ISBN: 978-3-031-18905-0Published: 07 January 2024

  • eBook ISBN: 978-3-031-18903-6Published: 04 January 2023

  • Edition Number: 1

  • Number of Pages: XXXII, 439

  • Number of Illustrations: 1 b/w illustrations, 60 illustrations in colour

  • Topics: Virology, Medical Microbiology, Biotechnology

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