19. Porto Carras, Chalkidiki, Greece, Aug. 31–Sept. 5, 1986

Published by De Gruyter 1987

19. Porto Carras, Chalkidiki, Greece, Aug. 31–Sept. 5, 1986

Edited by: Dimitrios Theodoropoulos

Part of the multi-volume work Peptides

https://doi.org/10.1515/9783110864243

Contents

Frontmatter Publicly Available Download PDF	I
Preface Publicly Available Download PDF	VII
Committees Publicly Available Download PDF	IX
The 19th European Peptide Symposium was supported by Publicly Available Download PDF	X
Contents Publicly Available Download PDF	XI
In memoriam Karel Jost /1932 - 1986/ Requires Authentication Unlicensed Licensed Download PDF	1
THE JOSEF RUDINGER MEMORIAL LECTURE: AN INTRODUCTORY NOTE G.T. Young Requires Authentication Unlicensed Licensed Download PDF	5
PREDICTION OF POTENCY AND RECEPTOR SELECTIVITY OF REGULATORY PEPTIDES: THE MEMBRANE COMPARTMENT CONCEPT FIRST JOSEF RUDINGER MEMORIAL LECTURE Robert Schwyzer Requires Authentication Unlicensed Licensed Download PDF	7
MAIN LECTURES
FROM PEPTONES TO PEPTIDES - A HISTORICAL RETROSPECT Joseph S. Fruton Requires Authentication Unlicensed Licensed Download PDF	25
KNOWLEDGE-BASED DESIGN OF NOVEL PEPTIDES T. L. Blundell Requires Authentication Unlicensed Licensed Download PDF	35
INSULIN-LIKE GROWTH FACTORS: STRUCTURE-ACTIVITY RELATIONSHIPS P.G. Katsoyannis, G.P. Schwartz, G.T. Burke, S. Joshi, M.M. Rechler and L.Y-H. Tseng Requires Authentication Unlicensed Licensed Download PDF	43
A. METHODOLOGY OF SYNTHESIS
PROTECTION
SELECTIVE REMOVAL OF THE 2—BROMOETHYL GROUP IN PEPTIDE SYNTHESIS M. Joaquina S.A. Amaral Trigo and M. Isabel A. Oliveira Santos Requires Authentication Unlicensed Licensed Download PDF	61
SELECTIVE PROTECTION OF CYSTEINE WITH FERROCENE DERIVATIVES C.N.C. Drey and A.S.J. Stewart Requires Authentication Unlicensed Licensed Download PDF	65
ADVANTAGES AND DISADVANTAGES IN THE USE OF FORMIC ACID IN PEPTIDE SYNTHESIS M. Galantino, E. Arlandini, R. Forino, G. Perseo and R. de Castiglione Requires Authentication Unlicensed Licensed Download PDF	69
DIBENZYL DICARBONATE (Z₂O) , A NEW CARBOBENZOXYLATING REAGENT W. Graf, O. Keller, W. Keller, G. Wersin and E. Witnsch Requires Authentication Unlicensed Licensed Download PDF	73
APPLICATION OF FLUORENYLMETHYL ESTERS IN THE SYNTHESIS OF VIRAL PROTEIN FRAGMENTS Alexander Kozhich, Andrey Ostrovsky and Vladimir Pozdnev Requires Authentication Unlicensed Licensed Download PDF	75
ELECTROCHEMICAL CLEAVAGE OF PROTECTING GROUPS H.L.S. Maia, M.J. Medeiros, M.I. Montenegro and D. Pletcher Requires Authentication Unlicensed Licensed Download PDF	79
AMMONOLYSIS MEDIATED SIDE REACTIONS OF ß-T-BUTYL-ASPARTYL PEPTIDES István Schőn and Attila Rill Requires Authentication Unlicensed Licensed Download PDF	83
THE PHENOTHIAZINYL-(10)-CARBONYL (PC) - RESIDUE, A NOVEL AMINO-PROTECTING GROUP FOR PEPTIDE SYNTHESIS J. Gante, W. Hechler and R. Weitzel Requires Authentication Unlicensed Licensed Download PDF	87
TETRACHLOROETHYL MIXED CARBONATES: THEIR USE IN THE SYNTHESIS OF PEPTIDES G. Sennyey, G. Barcelo, J.P. Senet, J. Martinez, M. Jaouadi, B. Castro and A. Loffet Requires Authentication Unlicensed Licensed Download PDF	91
TFMSA/TFA CLEAVAGE AND DEPROTECTION IN SPPS B. John Bergot, Richard F. Noble and Timothy Geiser Requires Authentication Unlicensed Licensed Download PDF	97
COUPLING: INCLUDING RACEMISATION
IS THERE HOPE THAT FOUR COMPONENT CONDENSATIONS WILL BECOME USEFUL FOR PEPTIDE AND PROTEIN CHEMISTRY ? I. Ugi, M. Baumeister, Ch. Fleck, R. Herrmann, R. Obrecht, F. Siglmüller and J.-H. Youn Requires Authentication Unlicensed Licensed Download PDF	103
USE OF FMOC AMINO ACID CHLORIDES IN THE SYNTHESIS OF TACHYKININ SEQUENCES AND INVESTIGATION OF THEIR HISTAMINE RELEASING ACTIVITY M. Beyermann, M. Bienert, H. Repke and L. A. Carpino Requires Authentication Unlicensed Licensed Download PDF	107
IMPROVED PREPARATION OF CRYSTALLINE N-(9-XANTHYL) AMINO ACID N-CARBOXYANHYDRIDES FOR PEPTIDE SYNTHESIS J. Halstrøm and K. Kovcás Requires Authentication Unlicensed Licensed Download PDF	111
THE OPTIMIZATION OF REACTION CONDITIONS FOR PEPTIDE SYNTHESIS BY MEANS OF N,N-BIS/2-OXO-3-OXAZOLIDINYL/PHOSPHORODIAMIDIC CHLORIDE A.M. Koƚodziejczyk and Z. J. Wodecki Requires Authentication Unlicensed Licensed Download PDF	115
APPLICATION OF MIXED PHOSPHINIC ANHYDRIDES IN FRAGMENT CONDENSATION OF PEPTIDES C. Poulos, Th. Tsegenidis and R. Ramage Requires Authentication Unlicensed Licensed Download PDF	119
A NEW PRINCIPLE FOR FRAGMENT CONDENSATION OF PEPTIDES K. Gunnarsson, L. Grehn and U. Ragnarsson Requires Authentication Unlicensed Licensed Download PDF	123
SYMMETRICAL ANHYDRIDE REARRANGEMENT LEADS TO THREE DIFFERENT DIPEPTIDE PRODUCTS N. L. Benoiton and F.M.F. Chen Requires Authentication Unlicensed Licensed Download PDF	127
POLYMER SUPPORTED PEPTIDE SYNTHESIS
ESTERS OF FMOC-AMINO ACIDS WITH 3,4,-DIHYDRO-3-HYDROXY-4-OXO-1,2,3-BENZOTRIAZINE. A NEW CLASS OF SELF-INDICATING, ACTIVATED INTERMEDIATES FOR SOLID PHASE SYNTHESIS Morten Meldal and Robert C. Sheppard Requires Authentication Unlicensed Licensed Download PDF	131
DESIGN OF REAGENTS FOR SOLID PHASE SYNTHESIS R. Ramage, S. Bielecki and M.J. Florence Requires Authentication Unlicensed Licensed Download PDF	135
SYNTHESIS OF THE CARBOHYDRATE-FREE VESPULAKININ 1 BY THE CONTINUOUS FLOW SOLID PHASE PROCEDURE AND BY A COMBINATION OF SOLID PHASE AND SOLUTION SYNTHESIS Rocchi R., L. Biondi, F. Filira and B. Scolaro Requires Authentication Unlicensed Licensed Download PDF	139
FACILE SOLID-PHASE PREPARATION OF PEPTIDES CONTAINING THE CH2NH PEPTIDE BOND ISOSTERE AND APPLICATION TO THE SYNTHESIS OF SOMATOSTATIN (SRIF) OCTAPEPTIDE ANALOGUES David H. Coy, Yusuke Sasaki, William A. Murphy and Mark Heiman Requires Authentication Unlicensed Licensed Download PDF	143
SYNTHESIS OF A KARYOPHILIC PEPTIDE COVALENTLY BOUND TO PHOSPHATIDYLETHANOLAMINE D. Lelièvre, A. Brack, Y. Trudelle, P.F. Tosi and C. Nicolau Requires Authentication Unlicensed Licensed Download PDF	147
GEL PHASE 13C NMR INVESTIGATION OF 'HYPER-HIGH LOAD' SOLID (GEL) PHASE SYNTHESIS OF AN LH-RH (1-5) ASSEMBLY R. Epton and D.A. Wellings Requires Authentication Unlicensed Licensed Download PDF	151
LIQUID PHASE PEPTIDE SYNTHESIS EMPLOYING A PHENOLIC MODIFICATION OF THE POLYETHYLENE GLYCOL SUPPORT Ian J. Galpin and Mark J. Wright Requires Authentication Unlicensed Licensed Download PDF	155
A COMPARISON OF DIFFERENT METHODS FOR THE PREPARATION OF BENZHYDRYLAMINE RESINS E. Pedroso, J. Josa, J-R. Peñalver and E. Giralt Requires Authentication Unlicensed Licensed Download PDF	159
THIOETHER LINKAGES BETWEEN PEPTIDE SYNTHETIC INTERMEDIATES AND SOLID SUPPORTS John D. Glass, Angeliki Buku and Chandra S. Pande Requires Authentication Unlicensed Licensed Download PDF	163
SOLID PHASE COUPLING OF PROTECTED PEPTIDE SEGMENTS. INFLUENCE OF THE POLYMER SUPPORT Fernando Albericio, Anna Porta, Enrique Pedroso and Ernest Giral Requires Authentication Unlicensed Licensed Download PDF	167
ATTEMPTS AT THE SYNTHESIS OF FOLLICLE STIMULATING HORMONE RELEASING PROTEIN (FRP) J. Rivier, C. Hoeger, R. Galyean and B. Penke Requires Authentication Unlicensed Licensed Download PDF	171
PEPTIDE CYCLIZATIONS ON POLYMERIC SUPPORTS - SITE ISOLATION VERSUS SITE - SITE INTERACTION M. Rothe, W. Fischer, K. Hornung, W. Taiber and G. Schmidtberg Requires Authentication Unlicensed Licensed Download PDF	175
SOLID PHASE PEPTIDE SYNTHESIS WITH FMOC-AMINO ACIDS AN ALTERNATIVE PROTOCOL J. Van Rietschoten, P. Fourquet, J.M. Sabatier and C. Granier Requires Authentication Unlicensed Licensed Download PDF	179
ENZYMATIC SYNTHESIS. SEMISYNTHESIS. RECOMBINANT SYNTHESIS
USE OF PROTEASES FOR THE SYNTHESIS OF LH-RH A.J. Andersen, F. Widmer and J.T. Johansen Requires Authentication Unlicensed Licensed Download PDF	183
BIOSYNTHESIS OF HUMAN INSULIN IN YEAST VIA SINGLE-CHAIN PRECURSORS Jan Markussen, Ulrik Damgaard, Ivan Diers, Niels Pill, Mogens Trier Hansen, Per Larsen, Fanny Norris, Kjeld Norris, Ole Schou, Leo Snel, Lars Thim and Hans Ole Voigt Requires Authentication Unlicensed Licensed Download PDF	189
STUDIES ON SYSTEM PROPERTIES INFLUENCING THE PARTITION CONSTANT IN KINETICALLY CONTROLLED ENZYMATIC PEPTIDE SYNTHESIS V. Schellenberger and H.-D. Oakubke Requires Authentication Unlicensed Licensed Download PDF	195
ENZYMATIC SYNTHESIS OF ASPARTAME. A STUDENT EXPERIMENT Gunnar Lindeberg Requires Authentication Unlicensed Licensed Download PDF	199
ENZYMATIC SYNTHESIS OP FRAGMENTS OF THE GONADOTROP RELEASING HORMONE MOLECULE WITH LH-RH/FSH-RH ACTIVITY L. Mladenova-Orlinova, I. Mancheva and J. Calderon Vera Requires Authentication Unlicensed Licensed Download PDF	203
NUCLEOPHILE BINDING IN CHYMOTRVPSIN PEPTIDE SYNTHESIS D.D. Petkov, E.K. Bratovanova and I.B. Stoineva Requires Authentication Unlicensed Licensed Download PDF	207
SYNTHESIS AND PROPERTIES OF [Hse⁶⁵, Ala ⁸¹], [Hse⁶⁵, Leu⁸¹ - and [Hse⁶⁵,Val⁸¹] - CYTOCHROME H.A. Boots and G.I. Tesser Requires Authentication Unlicensed Licensed Download PDF	211
ENZYMATIC SEMISYNTHESES WITH INSULIN: PREPARATION OF (ARG B31) INSULIN E. Krause and K.-D. Kaufmann Requires Authentication Unlicensed Licensed Download PDF	215
ENZYME-ASSISTED SEMISYNTHESIS OF POLYPEPTIDE ACTIVE ESTERS FOR SUBSEQUENT SPONTANEOUS COUPLING Keith Rose, Carlos Herrero, Amanda E.I. Proudfoot, Carmichael J.A. Wallace and Robin E. Offord Requires Authentication Unlicensed Licensed Download PDF	219
GENERAL METHODOLOGY: INCLUDING LABELLING, LARGE SCALE SYNTHESIS, ANALYSIS AND PURIFICATION
CHARACTERIZATION OF SYNTHETIC PEPTIDE HORMONE ANALOGS AND OF BYPRODUCTS L. Caporale, R. Nutt, J. Levy, M. Rosenblatt, J. Smith, B. Arison, W. Randall, C. Bennett, Albers-Schonberg G., S. Pitzenberger and R. Hirschmann Requires Authentication Unlicensed Licensed Download PDF	223
DDZ-, A HIGHLY EFFICIENT PROTECTING GROUP IN LARGE SCALE SYNTHESES OF THYMOSIN-alpha 1 RELATED PEPTIDES Nguyen-Trong Hao, Wolfgang Heinzel and Christian Birr Requires Authentication Unlicensed Licensed Download PDF	227
CHEMICAL SYNTHESIS OF TRICHOTOXIN, A MEMBRANE ACTIVE POLYPEPTIDE MYCOTOXIN H. Brückner Requires Authentication Unlicensed Licensed Download PDF	231
CHEMICAL PHOSPHORYLATION OF SERINE PEPTIDES RELATED TO SUBSTRATES OF CYCLIC AMP-DEPENDENT PROTEIN KINASE L. Grehn, B. Fransson, U. Ragnarsson and Ö. Zetterqvist Requires Authentication Unlicensed Licensed Download PDF	235
COMPARISON OF FOUR APPROACHES TO THE SYNTHESIS OF RAT ATRIAL NATRIURETIC POLYPEPTIDE (ANP) Nils Langeland Johansen, Peter Faarup and B.F. Lundt Requires Authentication Unlicensed Licensed Download PDF	239
SEQUENCE ANALYSIS OF THE ANTIBIOTIC EPIDERMIN, A HETERODET TETRACYCLIC 21-PEPTIDE AMIDE G. Jung, H. Allgaier, R.G. Werner, U. Schneider and H. Zähner Requires Authentication Unlicensed Licensed Download PDF	243
ISOLATION AND STRUCTURE IDENTIFICATION OF A NEW MAST CELL DEGRANULATING PENTADECAPEPTIDE FROM PARAI/E5PULA VULGARIS W.A. König, U. Schulze, K.D. Schräder, R. Chen and L. Grotjahn Requires Authentication Unlicensed Licensed Download PDF	247
PEPTIDES CONTAINING ɑɑ-DISUBSTITUTED AMINO ACIDS. EXPERIMENTS RELATED TO ɑ-HYDROXYMETHYLSERINE K. Kociolek, U. Slomczynska and M.T. Leplawy Requires Authentication Unlicensed Licensed Download PDF	251
PROTAMINES - VI. TOTAL SYNTHESIS OF [PERORNITHINE]-THYNNINE Z1 AND AMIDINATION STUDIES F. Marchiori, G. Borin, G. Chessa and A. Calderan Requires Authentication Unlicensed Licensed Download PDF	255
MULTIPLE POSITIONS 3H-LABELLING OF GROWTH HORMONE RELEASING FACTORS R. Genet, J. Diaz, P. Perreaut, A. Sasaki, P. Fromageot and J. L. Morgat Requires Authentication Unlicensed Licensed Download PDF	259
THE SYNTHESIS OF CYSTEINE-CONTAINING FRAGMENTS (RESIDUES 6-12 AND 13-20) OF CLOSTRIDIUM BUTXRICUM APOFERREDOXIN Brian Ridge and George Stavropoulos Requires Authentication Unlicensed Licensed Download PDF	263
LABELLED [pGlu⁴ , Cyt⁶]AVP-(4-8): FAILURE TO LABEL PROLINE WITH TRITIUM BUT SUCCESSFUL INTRODUCTION OF [³⁵S]CYSTEINE J.W. van Nispen, J.A.J. Hannink, F.M. Kaspersen and E.M.G. Sperlin Requires Authentication Unlicensed Licensed Download PDF	267
CONTRIBUTION TO LANTHIONINE AND CYCLOLANTHIONINE CHEMISTRY A. Yiotakis, A. Hatgiyannacou and I . Photaki Requires Authentication Unlicensed Licensed Download PDF	271
LARGE-SCALE SYNTHESIS OP GRF(1-29) AND (1-44) AMIDES Nagana A. Goud, Victor Garsky, Elizabeth Huelar, Firouz Shakoori, Mustaqim Syed and Michael S. Verlander Requires Authentication Unlicensed Licensed Download PDF	275
PRESS-STUD PROTEIN CONJUGATES R.E. Offord, S. Pochon and K. Rose Requires Authentication Unlicensed Licensed Download PDF	279
B. PHYSICAL STUDIES ON PEPTIDES
INTERNAL MOBILITY OF A CYCLIC PEPTIDE. A ROTATING FRAME RELAXATION STUDY K. D. Kopple and Y. - S. Wang Requires Authentication Unlicensed Licensed Download PDF	283
SYNTHETIC HELICAL PEPTIDES Eunice J. York, John M. Stewart, Robert L. Baldwin and Kevin R. Shoemaker Requires Authentication Unlicensed Licensed Download PDF	287
CONFORMATION—ACTIVITY RELATIONSHIPS IN THE SERIES OF MURAMYL—PEPTIDES S. Fermandjian, B. Perly, P. Sizun, M. Level and P. Lefrancier Requires Authentication Unlicensed Licensed Download PDF	291
NMR STUDY OF THYMULIN, A THYMIC NONAPEPTIDE HORMONE. INFLUENCE OF Zn(II) COMPLEXATION ON THE CONFORMATIONAL PROPERTIES M.T. Cung, M. Marraud, J.P. Laussac, M. Pasdeloup, R. Haran, P. Lefrancier, M. Dardenne and J.F. Bach Requires Authentication Unlicensed Licensed Download PDF	295
OXYGEN-17 NMR STUDIES OF ENKEPHALINS IN AQUEOUS SOLUTION I.P. Gerothanassis, T. Karayannis, M. Sakarellos-Daitsiotis, C. Sakarellos and M. Marraud Requires Authentication Unlicensed Licensed Download PDF	299
CONFORMATIONAL STUDY OF NEUROKININ A: COPARISON WITH SUBSTANCE P AND PHYSALAEMIN G. Chassaing, O. Convert and S. Lavielle Requires Authentication Unlicensed Licensed Download PDF	303
THE CONSTRUCTION OF NEW PROTEINS - DESIGN, SYNTHESIS AND CONFORMATIONAL PROPERTIES OF POLYPEPTIDES WITH ßɑß-TOPOLOGY M. Mutter, K.-H. Altmann, T. Vorherr and S. Vuilleumier Requires Authentication Unlicensed Licensed Download PDF	307
CONFORMATIONAL STUDIES ON THREE CYCLIC HEXAPEPTIDES RELATED TO THE SEQUENCE 7-11 OF SOMATOSTATIN G. Bovermann, L. Moroder, E. Wünsch, T. Tancredi, A. Motta, P.A. Temussi, D. Mierke, P. Lucietto and M. Goodman Requires Authentication Unlicensed Licensed Download PDF	311
STRUCTURAL VERSATILITY OF PEPTIDES FROM C^ɑ , ^ɑ-DIALKYLATED GLYCINES: Acc⁵ - AND Acc⁶-CONTAINING PEPTIDES E. Benedetti, V. Barone, A. Bavoso, B. Di Biasio, F. Lelj, V. Pavone and C. Pedone Requires Authentication Unlicensed Licensed Download PDF	315
SYNTHESIS AND X-RAY ANALYSIS OF OLIGOPEPTIDES CONTAINING ɑ-AMINOISOBUTYRIC ACID (AIB) M. Kokkinidis, D. Tsernoglou and H. Brückner Requires Authentication Unlicensed Licensed Download PDF	319
RENIN INHIBITORS AND SUBSTRATES: CONFORMATIONAL EFFECT OF PEPTIDE BACKBONE MODIFICATIONS G. Précigoux, Y. Barrans, S. Geoffre, P. Picard and M. Hospital Requires Authentication Unlicensed Licensed Download PDF	323
COMMON STRUCTURAL FEATURES FOR CYTOPROTECTION ACTIVITY OF CYCLIC RETRO ANALOGUES OF SOMATOSTATIN H. Kessler, A. Haupt, M. Klein and K. Wagner Requires Authentication Unlicensed Licensed Download PDF	327
SOLUTION CONFORMATION OF CONOTOXIN GI Y. Kobayashi, T. Ohkubo, I. Kyogoku, Y. Nishiuchi, S. Sakakibara and N. Go Requires Authentication Unlicensed Licensed Download PDF	331
PROTON MAGNETIC RESONANCE STUDIES OF ANGIOTENSIN II CONFORMATION: CHEMICAL SHIFTS FOR THE AROMATIC PROTONS OF SELECTED ANALOGUES IN DMSO—d₆ AT 40 0MZ. John M. Matsoukas, Mahesh H. Goghari and Graham J. Moore Requires Authentication Unlicensed Licensed Download PDF	335
CONFORMATIONAL STUDIES OF CARBA-ANALOGS OF OXYTOCIN M. Lebl, I. Fric, E.E. Sugg, W.L. Cody and V.J. Hruby Requires Authentication Unlicensed Licensed Download PDF	341
CONFORMATIONAL ANALYSIS OF CHOLECYSTOKININ CCK_27-33 AND CCK_26-33 BY ¹H NMR SPECTROSCOPY FLUORESCENCE TRANSFER MEASUREMENTS AND CALCULATIONS. M.C. Fournié-Zaluski, C. Durieux, B.P. Roques, B. Lux and B. Maigret Requires Authentication Unlicensed Licensed Download PDF	345
STUDY OF THE ß-TURN CONFORMATION IN PEPTIDES: AN INTRAMOLECULAR CHARGE-TRANSFER COMPLEXES APPROACH M. Sakarellos-Daitsiotis, G. Chassiotis, C. Sakarellos and B. Perly Requires Authentication Unlicensed Licensed Download PDF	349
SPECTROSCOPIC STUDIES OF SYNTHETIC PEPTIDE CHEMOATTRACTANTS G. Vertuani, M. Boggian and A. Scatturin Requires Authentication Unlicensed Licensed Download PDF	353
A 2D PROTON CONFORMATIONAL ANALYSIS OF TWO SYNTHETIC AMATOXINS ANALOGS Giancarlo Zanotti, Gabriella D’Auria, Livio Paolillo and Enrico Trivellone Requires Authentication Unlicensed Licensed Download PDF	357
SURFACTANT-INDUCED ORDERED STRUCTURES OF GASTRIN RELATED PEPTIDES N. Mammi, S. Mamtni, E. Peggion, L. Moroder, G. Bovermann and E. Wünsch Requires Authentication Unlicensed Licensed Download PDF	361
SYNTHESIS AND CONFORMATIONAL STUDY OF CYCLIC HEXAPEPTIDE ANALOGUES OF SOMATOSTATIN : Cyclo(Phe-D-Trp-Lys-Thr-o,m,p-AMPA) P. Vander Elst, E. van den Berg, D. Gondol, H. Pepermans, L. Van Der Auwera, C. Wynants, D. Tourwe and G. Van Binst Requires Authentication Unlicensed Licensed Download PDF	365
INVESTIGATION OF CARBAZOLCARBONYL-SUBSTITUTED POLY-ɑ-LYSINE, poly[N⁶(9H-carbazol-9-ylcarbonyl)-lysine] K. Brunfeldt, K. Kovâcs and F. Lauprêtre Requires Authentication Unlicensed Licensed Download PDF	369
BIOPHYSICAL PROPERTIES OF SYNTHETIC PRESEQUENCES SUGGEST CONFORMATIONS IMPORTANT FOR PROTEIN LOCALIZATION D.W. Hoyt, C.J. McKnight, M.S. Briggs, A.N. Stroup and L.M. Gierasch Requires Authentication Unlicensed Licensed Download PDF	373
C. BIOLOGICALLY ACTIVE PEPTIDES
NEUROPEPTIDES
HIGH AFFINITY AND IMPROVED SELECTIVITY FOR 6 OPIOID RECEPTORS EXHIBITED BY NEW LINEAR HEXAPEPTIDES G. Gaeel, J. Belleney, P. Delay-Goyet, C. Seguin, J.-L. Morgat and B.P. Roques Requires Authentication Unlicensed Licensed Download PDF	377
SYNTHESIS AND BIOLOGY OF CYCLIC ENKEPHALIN PSEUDOPEPTIDES Arno F. Spatola, Claudio Mapelli, Joseph Humphrey, J . Vincent Edwards, Thomas F. Burks and Jennifer E. Shook Requires Authentication Unlicensed Licensed Download PDF	381
DESIGN AND SYNTHESIS OF RECEPTOR SELECTIVE PEPTIDE NEUROTRANSMITTERS V.J. Hruby, L.-F. Kao, J. E. Shook, K. Gulya, H.I. Yamamura and T.F. Burks Requires Authentication Unlicensed Licensed Download PDF	385
SYNTHESIS AND STRUCTURE-ACTIVITY RELATIONSHIPS OF SIDE-CHAIN TO SIDE-CHAIN CYCLIZED OPIOID PEPTIDE ANALOGS P.W. Schiller, T.M.-D. Nguyen, L.A. Maziak, C. Lemieux and B.C. Wilkes Requires Authentication Unlicensed Licensed Download PDF	389
SYNTHESIS AND BIOLOGICAL ACTIVITY OF ENKEPHALIN RELATED GLYCOPEPTIDES J.M. Garcia Anton, J.L. Torres, G. Valencia, M.A. Busquests, F. Reig and R.E. Rodriguez Requires Authentication Unlicensed Licensed Download PDF	393
DESIGN, SYNTHESIS AND BIOLOGICAL ACTIVITY OF SELECTIVE AGONISTS FOR TACHYKININ RECEPTOR SUBTYPES M. Chorev, R. Laufer, D. Ron, J. Frey, U. Wormser, E. Rubini, Z. Selinger and C. Gilon Requires Authentication Unlicensed Licensed Download PDF	397
DISILOXANE-BRIDGED BIOLOGICALLY ACTIVE ANALOGUES OF THE ENKEPHALINS J.S. Davies, E.J. Tremeer and R.C. Treadgold Requires Authentication Unlicensed Licensed Download PDF	401
CHARACTERIZATION OF A THIRD TACHYKININ RECEPTOR (SP-N) IN THE MAMMALIAN NERVOUS SYSTEM R. Laufer, Z. Selinger, M. Chorev, J. Frey and C. Gilon Requires Authentication Unlicensed Licensed Download PDF	405
SYNTHESIS OF PEPTIDES CONTAINING REPEATING SEQUENCES OF ENKEPHALIN J. Izdebski, J. Bondaruk and P. Krzascik Requires Authentication Unlicensed Licensed Download PDF	409
SYNTHESIS AND BIOLOGICAL PROPERTIES OF PERIPLANETIN CC-2 COCKROACH NEUROPEPTIDE PROM CORPORA CARDIACA OP PERIPLANETA AMERICANA. L. D. Konopiriska, G. Rosinski, P. Sujak, A. Lesicki and A. Kasprzyk Requires Authentication Unlicensed Licensed Download PDF	413
A NOVEL µ—SPECIFIC REACTIVE LIGAND OF THE OPIATE RECEPTOR K. Medzihradszky, J. Hepp, S. Benyhe and A. Borsodi Requires Authentication Unlicensed Licensed Download PDF	417
STUDIES ON CARBOXYL TERMINALLY EXTENDED DERMORPHINS S. Salvadori, M. Marastoni, G. Balboni and R. Tomatis Requires Authentication Unlicensed Licensed Download PDF	421
SYNTHESIS OP ANALOGS OP ENKEPHALIN DERIVATIVES OP 2-D-ALA,5-DESMET- ENKEPHALIN HYDRAZIDE AT THE FIRST AND FOURTH POSITIONS G. P. Vlasov, N.Yu. Kozhevnikova, E.N. Krasnikova and N.G. Illarionova Requires Authentication Unlicensed Licensed Download PDF	425
SYNTHESIS AND PRELIMINARY BIOLOGICAL RESULTS OF DIMERIC DERMORPHIN- -LIKE PEPTIDES R. de Castiglione, G. Perseo, R. Mena, G. Falconieri Erspamer and L. Negri Requires Authentication Unlicensed Licensed Download PDF	431
ENKEPHALIN ANALOGUES CONTAINING POLAR AMINO ACID RESIDUES G. W. Hardy, L. A. Lowe and T. W. Smith Requires Authentication Unlicensed Licensed Download PDF	435
CONFORMATIONS OF TACHYKININ PEPTIDES IN MEMBRANE ENVIRONMENTS G. Andrew Woolley and Charles M. Deber Requires Authentication Unlicensed Licensed Download PDF	439
CONFORMATION ACTIVITY RELATIONSHIP OF A SERIES OF PEPTIDES RELATED TO DERMORPHIN. A 500 MHz NMR STUDY M.A. Castiglione-Morelli, T. Tancredi, E. Trivellone, S. Salvadori, R. Tomatis and P. A. Temussi Requires Authentication Unlicensed Licensed Download PDF	443
GASTROINTESTINAL PEPTIDES
SYNTHESIS OF CHOLECYSTOKININ PEPTIDES B. Penke, M. Zarandi, J. Zsigo, G.K. Toth, K. Kovacs and G. Telegdy Requires Authentication Unlicensed Licensed Download PDF	447
CYCLIC HEXAPEPTIDE CCK ANTAGONISTS R. M. Freidinger, W. L. Whitter, R. S. L. Chang, V. J. Lotti and D. F. Veber Requires Authentication Unlicensed Licensed Download PDF	451
SYNTHESIS OF PSEUDO-PEPTIDE AND PEPTIDE ANALOGUES OF THE C-TERMINAL HEPTAPEPTIDE OF CHOLECYSTOKININ AND PRELIMINARY RESULTS ON THEIR IN VITRO ACTIVITY ON RAT PANCREATIC ACINI M. Rodriguez, M.F. Lignon, M.C. Galas, C. Mendre and J. Martinez Requires Authentication Unlicensed Licensed Download PDF	455
ANTERIOR AND POSTERIOR PITUITARY PEPTIDES
SURPRISING FINDINGS WITH SOME DELETION-MODIFIED SELECTIVE V2 ANTAGONISTS OF ARGININE VASOPRESSIN M. Manning, J. Przybylski, B. Lammek, Z. Grzonka, A. Olma, K. Bankowski, A. Misicka, M. Kruszynski and W.H. Sawyer Requires Authentication Unlicensed Licensed Download PDF	459
VASOPRESSIN ANALOGS WITH STRONG AGONISTIC - ANTAGONISTIC PROPERTIES M. Zaoral, I. Blaha, M. Lebl and T. Barth Requires Authentication Unlicensed Licensed Download PDF	465
PHOTOREACTIVE AGONISTS AND ANTAGONISTS OF NEUROHYPOPHYSIAL HORMONES FOR RECEPTOR STUDIES F. Fahrenholz, E. Kojro and R. Boer Requires Authentication Unlicensed Licensed Download PDF	469
AC TH-PHOTOAFFINITY LABELS, SYNTHESIS AND APPLICATION OF ANALOGUES WITH AGONISTIC AND PARTIAL AGONISTIC PROPERTIES E. Escher, Z. Mackiewicz, S. Sircar, D. Bourque, F. Bouthillier and J.-G. Lehoux Requires Authentication Unlicensed Licensed Download PDF	473
THE INFLUENCE OF PEPTIDE-RECEPTOR DISSOCIATION RATE CONSTANTS ON RESPONSES TO AND APPARENT POTENCY OF PEPTIDE HORMONES Diana Gazis Requires Authentication Unlicensed Licensed Download PDF	477
SYNTHESIS AND BIOLOGICAL ACTIVITY OF NOVEL GROWTH HORMONE RELEASING FACTOR ANALOGS A.M. Felix, E.P. Heimer, T.F. Mowles, H. Eisenbeis, P. Leung, T.J. Lambros, M. Ahmad, C.-T. Wang and P. Brazeau Requires Authentication Unlicensed Licensed Download PDF	481
SYNTHESIS AND BIOLOGICAL ACTIVITIES OF THREE ARGININE VASOPRESSIN ANALOGS WITH 4-HYDR0XYPR0LINE IN POSITION 7 Diana Gazis, Angeliki Buku, John D. Glass, Irving L. Schwartz and Herman R. Wyssbrod Requires Authentication Unlicensed Licensed Download PDF	485
STUDIES WITH PEPTIDES RELATED TO THE SEQUENCE 4-9 OF ACTH R. Geiger, H.J. Gerhards, G. Wiemer and F.J. Hock Requires Authentication Unlicensed Licensed Download PDF	489
STRUCTURE-ACTIVITY RELATIONSHIPS OF VASOPRESSIN: SYNTHESES OF NEW VASOPRESSIN ANALOGUES Zbigniew Grzonka, Leszek Lankiewicz, Franciszek Kasprzykowski, Adam Liwo and Per Melin Requires Authentication Unlicensed Licensed Download PDF	493
OXYTOCIN ANALOGS CONTAINING TWO DISULFIDE BONDS J. Hlavácek, J. Konvalinka, J. Slaninova and I. Frič Requires Authentication Unlicensed Licensed Download PDF	497
SYNTHESIS OF ALA-SUBSTITUTED ANALOGS OF ACTH/αMSH-(4-10) AND THEIR EFFECTS ON STEROIDOGENESIS AND PIGMENT DISPERSION M. Lȍw, L. Kisfaludy, K. Sz. Szalay and H. Medzihradszky-Schweiger Requires Authentication Unlicensed Licensed Download PDF	501
SYNTHESIS AND BIOLOGICAL ACTION OF ACTH-MSH FRAGMENTS CONTAINING MELPHALAN H. Medzihradszky-Schweiger, H. Suli-Vargha, J. Botyinszki and K. Medzihradszky Requires Authentication Unlicensed Licensed Download PDF	505
NOVEL GnRH AGONISTS CONTAINING L-β-ASPARTIC ACID DERIVATIVES IN POSITION 6 J. Seprődi, J. Érchegyi, Zs. Vadász, I. Teplán and B. Kanyicska Requires Authentication Unlicensed Licensed Download PDF	509
CHARACTERIZATION OF NOVEL SPECIES SPECIFIC GnRH ANALOGS WHICH CAN BE USED FOR THE INDUCED ARTIFICIAL PROPAGATION OF FISHES Gy. Kéri, A. Horváth, T. Gulyäs and I. Teplán Requires Authentication Unlicensed Licensed Download PDF	513
PANCREATIC PEPTIDES
SYNTHETIC PEPTIDE ANTAGONISTS OF GLUCAGON R.B. Merrifield, C. Unson, E.M. Gurzenda and D. Andreu Requires Authentication Unlicensed Licensed Download PDF	517
NEW PHOTO-REACTIVE DERIVATIVES OF INSULIN FOR AFFINITY-LABELLING OF THE INSULIN RECEPTOR D. Ambrosius, S. Bala-Mohan, C. Behrendt, K. Schäfer, A. Schüttler and D. Brandenburg Requires Authentication Unlicensed Licensed Download PDF	521
SELECTIVE N- AND C-TERMINAL ELONGATION AT A1 AND B30 OF INSULIN: NEW APPROACHES TO PROINSULIN RELATED CONVERSION INTERMEDIATES V. K. Naithani, H.-G. Gattner and H. Zahn Requires Authentication Unlicensed Licensed Download PDF	525
SYNTHESIS OF GLUCAGON-LIKE PEPTIDES: DEVELOPMENT OF SPECIFIC ANTISERA AND ANALYSIS OF PROGLUCAGON PROCESSING S. Mojsov and J. F. Habener Requires Authentication Unlicensed Licensed Download PDF	529
STRUCTURE-ACTIVITY STUDIES OF SOMATOSTATIN AHALOGS, SUBSTITUTED AT POSITIONS 4 AND 5 D. Sarantakis Requires Authentication Unlicensed Licensed Download PDF	535
SYNTHESIS OF SOMATOSTATIN ANALOGUES OF REDUCED SUSCEPTIBILITY TOWARDS INTESTINAL ENZYMES Mark C Allen and Roy Wade Requires Authentication Unlicensed Licensed Download PDF	539
IMMUNOPEPTIDÉS
PEPTIDE CONJUGATES AS DIAGNOSTIC REAGENTS IN CLINICAL IMMUNOLOGY H. Rolli and C. H. Schneider Requires Authentication Unlicensed Licensed Download PDF	543
PREDICTION OF HUMAN RENIN EPITOPES USING A NEW COMPUTER ALGORITHM Genevieve Evin, William D. Carlson, Mark Handschumacher, Jiri Novotny, Edgar Haber, Francois-Xavier Galen, Jacob Bouhnik, Joel Menard and Pierre Corvol Requires Authentication Unlicensed Licensed Download PDF	549
DESIGN AND SYNTHESIS OF IMMUNOGENIC COMPLEXES BUILT UP OF A PEPTIDE ANTIGEN, GLYCOPEPTIDE ADJUVANT AND POLYMER CARRIER T.M. Andronova, V.A. Rar, E.A. Makarov and V.T. Ivanov Requires Authentication Unlicensed Licensed Download PDF	553
THYMULIN ANALOGUES FOR PROBING SPECIFIC BINDING SITES ON LYMPHOBLASTOID CELLS Didier Blanot, Louis-Nöel Gastinel, Mireille Dardenne and Jean-François Bach Requires Authentication Unlicensed Licensed Download PDF	557
SYNTHESIS AND PHARMACOLOGICAL PROPERTIES OF ADAMANTYLAMIDE ANALOGS OF MÜRAMYL-DIPEPTIDE (MDP). M. Flegel, J. Seifert, H. Farghali, K. Masek and M. Krojidlo Requires Authentication Unlicensed Licensed Download PDF	561
IMMUNOGENICITY OF HEPATITIS B SURFACE ANTIGEN SYNTHETIC PEPTIDE ANALOGUES B. Lammek, G. Kupryszewski, U. Ragnarsson, H. Świderska, M. Jastrzebska and A. Nowosławski Requires Authentication Unlicensed Licensed Download PDF	565
SYNTHESIS AND ANTIGENIC PROPERTIES OF PEPTIDES CORRESPONDING TO 200-210 SEQUENCE OF p28^sisONCOPROTEIN. COMPARATIVE STUDY OF N^G-PROTECTING GROUPS I.I. Mikhaleva, V.V. Antonenko, I.A. Prudchenko and N.N. Mazurenko Requires Authentication Unlicensed Licensed Download PDF	569
SYNTHETIC SEQUENCES OF CHOLERA TOXIN B SUBUNIT ARE IMMUNOGENIC PER OS AND DO NOT INDUCE ORAL TOLERANCE S. Pedoussaut, A. Guyon-Gruaz, A. Delmas, H. Halimi, G. Milhaud and P. Rivaille Requires Authentication Unlicensed Licensed Download PDF	573
SYNTHESIS OF LARGE NUMBERS OF COVALENTLY BOUND PEPTIDES IN ORDER TO DETERMINE THE SPECIFICITY OF PEPTIDE ANTISERA AT THE LEVEL OF SINGLE AMINO ACIDS W. M. M. Schaaper, H. Lankhof, D. J. A. Meijer, W.C. Puijk and R. H. Meloen Requires Authentication Unlicensed Licensed Download PDF	577
SYNTHESIS AND IMMUNOLOGICAL ACTIVITY OF PEPTIDES OF THE THYMUS GLAND W. Voelter, H. Echner, H. Kaibacher, T.Q. Dinh, A. Kapurniotu, M. Jahan, G. Grübler, P. Link, M. Mihelic and W. Stock Requires Authentication Unlicensed Licensed Download PDF	581
STRUCTURE-ACTIVITY RELATIONSHIPS STUDIES OF DIPHTHERIA TOXIN USING SYNTHETIC PEPTIDES THAT ELICIT TOXIN-REACTIVE ANTIBODIES A. Michel and D. Muyshont Requires Authentication Unlicensed Licensed Download PDF	585
ENZYME SUBSTRATES AND INHIBITORS
PREPARATION OF SUBSTRATE INHIBITORS OF THE AMIDATING ENZYME IN PORCINE PITUITARY A.F. Bradbury and D.G. Smyth Requires Authentication Unlicensed Licensed Download PDF	591
RE-APPRAISAL OF THE SERINE PROTEASE CATALYTIC MECHANISM: POSSIBLE INVOLVEMENT OF AN ACYL-HISTIDINE INTERMEDIATE Graham J. Moore Requires Authentication Unlicensed Licensed Download PDF	595
PREPARATION AND PROPERTIES OF SELECTIVELY ε-NH₂ ACYLATED PANCREATIC PHOSPHOLIPASES A₂ Arend J. Slotboom, Frans van der Wiele, Wim Atsma, Jan van Binsbergen, Margreet van Linde, Ben Roelofsen and Gerard H. de Haas Requires Authentication Unlicensed Licensed Download PDF	601
INTRAMOLECULARLY QUENCHED FLUOROGENIC SUBSTRATES FOR AMINOPEPTIDASE P IN HUMAN SERUM E. J. Holtzman and A. Yaron Requires Authentication Unlicensed Licensed Download PDF	605
SENSITIVE CHYMOTRYPSIN DETERMINATION USING FLUOROGENIC SUBSTRATES CONTAINING 2-QUINOLINONE DERIVATIVES G. Kokotos, C. Tzougraki and R. Geiger Requires Authentication Unlicensed Licensed Download PDF	611
OTHER BIOLOGICALLY ACTIVE PEPTIDES
SYNTHESIS OF GLYCOPEPTIDES USING THE ALLYL ESTER AND THE ALLYLOXYCARBONYL GROUP AS PROTECTING FUNCTIONS Horst Kunz, Herbert Waldmann and Carlo Unverzagt Requires Authentication Unlicensed Licensed Download PDF	615
EVALUATION OF RECEPTOR SITES FOR PLASMODIUM FALCIPARUM (MALARIA) ON HUMAN ERYTHROCYTES. CHEMICAL SYNTHESIS OF PEPTIDES RELEVANT TO GLYCOPHORIN A. A. Tounkara, F. Piller, D. Blanchard, J.P. Cartron, B. Ferrari, J.M. Lacombe and A. Pavia Requires Authentication Unlicensed Licensed Download PDF	619
STRUCTURAL REQUIREMENTS FOR DESENSITIZATION OF SMOOTH MUSCLE TO ANGIOTENSIN II M.E.M. Oshiro, T.B. Paiva, C.R. Nakaie and A.C.M. Paiva Requires Authentication Unlicensed Licensed Download PDF	623
STRUCTURE ACTIVITY RELATIONSHIP ON NEW PEPTIDE INHIBITORS ON THE ANGIOTENSIN CONVERTING ENZYME S. Reißmann, C. Schwuchow, H. Arold, H.P. Filatova, H.A. Krit, W.-E. Siems, G. Heder and I. Paegelow Requires Authentication Unlicensed Licensed Download PDF	627
FURTHER SYNTHETIC STUDIES ON POSITION 1 OF ANGIOTENSIN II P. Cordopatis and D. Theodoropoulos Requires Authentication Unlicensed Licensed Download PDF	633
CONFIRMATION OF DIMERIC STRUCTURE OF HUMAN BETA-ATRIAL NATRIURETIC POLYPEPTIDE (ß-hANP) BY SYNTHESIS Tamayo Hatoh, Kenji Kangawa and Hisayuki Matsuo Requires Authentication Unlicensed Licensed Download PDF	637
SMALL PEPTIDES MAY BE TISSUE SPECIFIC MITOSIS INHIBITORS INDUCING TERMINAL DIFFERENTIATION K.L. Reichelt, K. Elgjo, J.E. Paulsen and Ø. Skraastad Requires Authentication Unlicensed Licensed Download PDF	641
SYNTHESIS AND BIOLOGICAL PROPERTIES OF ANTIPARALLEL AND PARALLEL DIMERS OF α-HUMAN ATRIAL NATRIURETIC PEPTIDE Naoyoshi Chino, Kumiko Yoshizawa-Kumagaye, Yuko Nöda, Takushi X. Watanabe, Terutoshi Kimura and Shumpei Sakakibara Requires Authentication Unlicensed Licensed Download PDF	647
STRUCTURE-ACTIVITY RELATIONSHIP OF LEPIDOPTERAN, SELF-DEFENCE PEPTIDE PRODUCED BY SILKWORM T. Shiba, T. Nakai, M. Kitazawa and T. Teshima Requires Authentication Unlicensed Licensed Download PDF	651
BRADYKININ ANTAGONISTS CONTAINING HYDROXYPROLINE Raymond J. Vavrek and John M. Stewart Requires Authentication Unlicensed Licensed Download PDF	655
D. MISCELLANEOUS: INCLUDING STRUCTURAL INVESTIGATION
SYNTHESIS OF CHIRAL TETRAMIC ACID. THE INTERMEDIATE IN THE STEREOCONTROLLED PREPARATION OF STATINE ANALOGUES. KEY COMPONENTS IN ASPARTIC PROTEINASES INHIBITORS P. Jouin, B. Castro, J. Poncet and D. Nisato Requires Authentication Unlicensed Licensed Download PDF	659
AMINO ACIDS ON THE BASIS OF CYCLIC β-DIKETONES - SYNTHESIS AND PHOTOPHYSICAL CHARACTERISTICS St. Minchev, N. Sofroniev, I. Timtcheva and F. Nikolov Requires Authentication Unlicensed Licensed Download PDF	663
Participants Requires Authentication Unlicensed Licensed Download PDF	667
Authors' Index Requires Authentication Unlicensed Licensed Download PDF	677
Subject Index Requires Authentication Unlicensed Licensed Download PDF	681

Language: German
Publisher: De Gruyter
Edition: Reprint 2019
Pages
- Front matter: 19
- Main content: 684
Illustrations
- Other: Num. figs. and tables
Keywords: Peptide; Kongress

eBook

Published: October 8, 2019
ISBN: 9783110864243

Hardcover

Published: May 1, 1987
ISBN: 9783110106879