Vitamin D. Basic Research and its Clinical Application: Proceedings of the Fourth Workshop on Vitamin D, Berlin, West Germany, February 1979

Published by De Gruyter 1979

Vitamin D. Basic Research and its Clinical Application

Proceedings of the Fourth Workshop on Vitamin D, Berlin, West Germany, February 1979

Edited by: A. W. Norman , K. Schaefer , D. v. Herrath , H.-G. Grigoleit , J. W. Coburn , H. F. De Luca , E. B. Mawer and T. Suda

https://doi.org/10.1515/9783112330029

Contents

Frontmatter Publicly Available Download PDF	I
Foreword Publicly Available Download PDF	V
Contents Publicly Available Download PDF	IX
Chemistry, Structure, Function and Biological Assay
Introduction Requires Authentication Unlicensed Licensed Download PDF	1
Synthesis of Some Side Chain Analogues of Vitamin D₃ Metabolites N. Ikekawa, M. Morisaki, N. Koizumi and Y. Hirano Requires Authentication Unlicensed Licensed Download PDF	13
Structural Transformations on Vitamin D E. Zbiral and W. Reischl Requires Authentication Unlicensed Licensed Download PDF	21
Distribution and Activity of a Vitamin D₃ Compound in Trisetum Flavescens W. A. Rambeck, A. Wetzel, O. Kreutzberg and H. Zucker Requires Authentication Unlicensed Licensed Download PDF	33
Synthesis and Biological Activity of 24R-Hydroxy-25-fluorocholecalciferol and 1a, 24R-Dihydroxy-25-fluorocholecalciferol J. J. Partridge, S.-J. Shiuey, A. Boris, J. P. Mallon and M. R. Uskokovic Requires Authentication Unlicensed Licensed Download PDF	37
The Synthesis and Biological Evaluation of Fluorinated Analoges as Probes of Vitamin Da Metabolism J. L. Napoli, W. S. Mellon, M. A. Fivizzani, H. K. Schnoes and H. F. De Luca Requires Authentication Unlicensed Licensed Download PDF	45
19-Substituted-10,19-Dihydrovitamins via Hydrozirconation of Vitamin D₃ A. W. Messing, F. P. Ross, M. Miura, A. W. Norman and W. H. Okamura Requires Authentication Unlicensed Licensed Download PDF	51
The Synthesis of 1a, 3a-Dihydroxy-25Methylcholesta-5,7-Diene-24-OIC Acid, and of la, 3a-Dihydroxy-25 Methylcholesta-5,7-Diene J. M. Midgley, R. M. Upton, R. Watt and W. B. Whalley Requires Authentication Unlicensed Licensed Download PDF	55
Interconversion of Vitamin D and Trans-Vitamin D by Triplet-Sensitized Isomerization H. J. C. Jacobs, J. W. J. Gielen and E. Havinga Requires Authentication Unlicensed Licensed Download PDF	61
The Use of UV, CD, ²H-NMR Spectroscopy and Mass Spectrometry for the Investigation of Conformational Mobility of Vitamin D and Previtamin D and their Interconversion E. Berman, N. Friedman, Y. Mazur, M. Sheves and Zeev V. I. Zaretskii Requires Authentication Unlicensed Licensed Download PDF	65
25 (R), 26 and 25 (S), 26-(OH)₂D₃: Biological Activity in Intact and Nephrectomized Rats. Comparative Effects of 1, 25, 24 (R), 25-(OH)₂D₃ and I, 24 (R), 25-(OH)₃D₃ M. Thomasset, J. Redel, P. Marche and P. Cuisinier-Gleizes Requires Authentication Unlicensed Licensed Download PDF	73
Inhibitors of Vitamin D Metabolism and Action B. L. Onisko, H. K. Schnoes and H. F. De Luca Requires Authentication Unlicensed Licensed Download PDF	77
C(1)-Hydroxylation of Vitamin D₃ and Related Compounds H. E. Paaren, H. K. Schnoes and H. F. De Luca Requires Authentication Unlicensed Licensed Download PDF	81
Vitamin D₃ Sulfate in Lactating normally fed Rats and Suckling Pups After Maternal Administration of ³H Vitamin D₃ or ³⁵S Vitamin D3 Sulfate N. Le Boulch, M. Laromiguiere, C. Marnay-Gulat, L. Miravet and Y. Raoul Requires Authentication Unlicensed Licensed Download PDF	85
Synthesis of Vitamin D Analogues and their Covalent Binding to Affinity Chromatographic Media F. P. Ross, W. R. Wecksler, W. H. Okamura and A. W. Norman Requires Authentication Unlicensed Licensed Download PDF	89
Osteoporosis
Calcium Absorption and Plasma 1,25 (OH)₂D Levels in Post-Menopausal Osteoporosis B. E. C. Nordin, M. Peacock, R. G. Crilly and D. H. Marshall Requires Authentication Unlicensed Licensed Download PDF	99
Osteoporosis and Age-Related Osteopenia: Evaluation of Possible Role of Vitamin D Endocrine System in Pathogenesis of Intestinal Calcium Absorption B. L. Riggs, J. C. Gallagher and H. F. De Luca Requires Authentication Unlicensed Licensed Download PDF	107
Two Years Experience of Oral Treatment with 1a-Hydroxyvitamin D and Calcium in Patients with Senile or Postmenopausal Osteoporosis T. S. Lindholm Requires Authentication Unlicensed Licensed Download PDF	115
The Treatment of Osteoporosis with 24,25 Dihydroxycholecalciferol A Pilot Study J. Reeve, R. Hesp, P. Hulme, J. A. Kanis, L. Klenerman, P. Meunier, R. G. G. Russell, M. Tellez-Yudilevich, D. Williams and R. Wootton Requires Authentication Unlicensed Licensed Download PDF	119
Osteomalacic Factors in the Osteoporosis and the Treatment of Osteoporotic Patients with Vitamin D₂ and 1aOHD₃ K. Mizuno and J. Tanaka Requires Authentication Unlicensed Licensed Download PDF	123
Transcalciferan/D-Binding Protein(s)
Biologic Significance of Genetic Variation in Human Gc (Vitamin D-Binding Protein) S. P. Daiger Requires Authentication Unlicensed Licensed Download PDF	129
The Transport of Vitamin D R. Bouillon and H. Van Baelen Requires Authentication Unlicensed Licensed Download PDF	137
Structure and Properties of Human Plasma Vitamin D Transport Protein (Group-Specific Component) J. Svasti, A. Kurosky, A. Bennett, R. Surarit and B. H. Bowman Requires Authentication Unlicensed Licensed Download PDF	149
Serum Vitamin D Binding and Gc Polymorphism J. Constans, M. Viau, J. P. Moatti and J. L. Clavere Requires Authentication Unlicensed Licensed Download PDF	153
Sunlight, Skin and Seasonal Effects
Identification of in Vivo Generated Previtamin D₃, Vitamin D₃ and 25-Hydroxyvitamin D₃ in the Vitamin D-Deficient Rats Irradiated by Ultraviolet Light T. Kobayashi, T. Okano, K. Mizuno, N. Matsuyama, N. Nobuhara, K. Takada and T. Takao Requires Authentication Unlicensed Licensed Download PDF	159
Response of Plasma 250HD to Standardized Ultra Violet Radiation M. Davie and D. E. M. Lawson Requires Authentication Unlicensed Licensed Download PDF	163
Effects of Sunlight Exposure on Blood Concentration of Vitamin D Derivatives in Healthy Japanese Adults R. Morita, S. Dokoh, M. Fukunaga, I. Yamamoto and K. Torizuka Requires Authentication Unlicensed Licensed Download PDF	165
Contribution of Skin Vitamin D₃ Synthesis in Patients Receiving Total Parenteral Nutrition G. Jones, B. Byrnes, D. Duthie and K. N. Jeejeebhoy Requires Authentication Unlicensed Licensed Download PDF	169
The Photo-Biochemistry of Vitamin D₃ in Vivo in the Skin M. F. Holick, S. A. Holick, S. M. McNeill, N. Richtand, M. B. Clark and J. T. Potts Requires Authentication Unlicensed Licensed Download PDF	173
Assays for Vitamin D Metabolites
Measurement of Plasma 1,25 (OH)₂ Vitamin D by Protein Binding Assay and Radioimmunoassay M. Peacock, G. A. Taylor and W. B. Brown Requires Authentication Unlicensed Licensed Download PDF	179
Use of Isotope Dilution Mass Fragmentography in Vitamin D Research I. Björkhem, I. Holmbeg, T. Kristiansen, A. Larsson and J. I. Pedersen Requires Authentication Unlicensed Licensed Download PDF	183
Assay of 1,25-Dihydroxyvitamin D and Other Active Vitamin D Metabolites in Serum: Application to Animals and Humans M. R. Haussler, M. K. Drezner, J. W. Pike, J. S. Chandler and L. A. Hagan Requires Authentication Unlicensed Licensed Download PDF	189
24,25-Dihydoxyvitamin D in Human Serum C. M. Taylor Requires Authentication Unlicensed Licensed Download PDF	197
Radioimmunoassay of Vitamin D Metabolites P. C. Schaefer and R. S. Goldsmith Requires Authentication Unlicensed Licensed Download PDF	205
Assays for Vitamin D and its Metabolites R. L. Horst, R. M. Shepard, N. A. Jorgensen and H. F. De Luca Requires Authentication Unlicensed Licensed Download PDF	213
Radioimmunoassay for Circulating 1,25- and 25,26-Dihydroxycholecaliferols in Man J. L. H. O’Riordan, T. L. Clemens, G. N. Hendy, L. J. Fraher, L. M. Sandler and S. E. Papapoulos Requires Authentication Unlicensed Licensed Download PDF	221
Hemisuccinates of Vitamin D₃ and of its Metabolites K. Lichtwald, E. Mayer, H. Schmidt-Gayk, J. Varga and S. Walch Requires Authentication Unlicensed Licensed Download PDF	229
Studies on Antisera against Vitamin D Metabolites H. Schmidt-Gayk, E. Mayer, R. Schjier, K. Lichtwald, R. Bouillon and T. L. Clemens Requires Authentication Unlicensed Licensed Download PDF	233
The Measurement of Various Vitamin D Derivatives in Plasma Using High-Pressure Liquid Chromatography S. Dokoh, R. Morita, M. Fukunaga, I. Yamamoto, A. Miyaji and K. Torizuka Requires Authentication Unlicensed Licensed Download PDF	239
Assay of 1,25- and 24,25 Dihydoxycholecalciferol in Human Serum - some Technical Considerations R. S. Mason, D. Lissne, C. Reek and S. Posen Requires Authentication Unlicensed Licensed Download PDF	243
Radiocompetitive Protein Binding Assays for 25-Hydroxy Vitamin D, 24,25-Dihydroxyvitamin D and 1,25-Dihydroxy-vitamin D in Human Serum S. Guillemant, R. Kremer, J. Eurin and J. Guillemant Requires Authentication Unlicensed Licensed Download PDF	247
Steroid Receptors: What do We not Know? R. J. B. King Requires Authentication Unlicensed Licensed Download PDF	251
Vitamin D - Parathyroid Hormone
Cholecalcifediol suppression of PTH Secretion from Monolayer Culture of Human Parathyroid Carcinoma Cells M. Fukase, M. Tsutsumi, J. Iwasaki and T. Fujita Requires Authentication Unlicensed Licensed Download PDF	261
The Effect of Human Growth Hormone Replacement on Parathyroid Function and Vitamin D Metabolism J. M. Gertner, R. L. Horst, M. Genel and H. Rasmussen Requires Authentication Unlicensed Licensed Download PDF	265
Serum Calcium Concentration: Possible Regulator of Renal Parathyroid Hormone Action H. V. Lilienfeld-Toal, K. G. Mackes and E. Keck Requires Authentication Unlicensed Licensed Download PDF	267
Effects of Vitamin D3 Metabolites Injection into Thyro-parathyroidectomized Pregnant Rats on Fetal Weight and Liver Glycogen Stores in Mothers and Fetuses J. M. Garel, M. Gilbert and P. Besnard Requires Authentication Unlicensed Licensed Download PDF	271
Effects of Vitamin Deficiency on Calcium-Binding Proteins and on Plasma Calcitonin and Parathyroid Hormone Levels in Growing Pigs A. Pointiiiart, M. Thomasset and J. M. Garel Requires Authentication Unlicensed Licensed Download PDF	275
1,25 Dihydroxycholecalciferol effect on in Vitro Immunoreactive Human Parathyroid Hormone Secretion from Hyperplastic Glands E. Mallet, J. P. Basuyau, M. C. Tonon and H. Vaudry Requires Authentication Unlicensed Licensed Download PDF	279
Quantitative Changes of Rat Thyroid C Cell Population in Hyper- and Hypovitaminosis D M. Petko Requires Authentication Unlicensed Licensed Download PDF	285
The Interactions Between Vitamin D Metabolites, Parathyroid Hormone and Calcitonin A. D. Care, D. W. Pickard, S. E. Papapoulos, J. L. H. O’Riordan, J. M. Garel and J. Redel Requires Authentication Unlicensed Licensed Download PDF	289
In Vivo Suppression of Parathyroid Hormone Secretion by 24,25 Dihydroxy Cholecalciferol in Hyperparathyroid Dogs J. M. Canterbury, G. Gavellas, J. J. Bourgoignie and E. Reiss Requires Authentication Unlicensed Licensed Download PDF	297
Renal Actions
Acute and Chronic Effects of Vitamin D Metabolites on the Renal Handling of Phosphate J.-P. Bonjour, J. Caverzasio, H. Fleisch and U. Trechsel Requires Authentication Unlicensed Licensed Download PDF	307
Interaction of Vitamin D Metabolites with Parathyroid Hormone and Vasopressin J. B. Puschett Requires Authentication Unlicensed Licensed Download PDF	315
Phosphaturie Effect of Parathyroid Hormone in Phosphate Depleted Man J. C. Pena, J. Guerrero, S. Quiröz and J. Herrera Requires Authentication Unlicensed Licensed Download PDF	325
Vitamin D in Maternal, Fetal and Neonatal Conditions
Long Term Effects of Low 25-Hydroxyvitamin D (25-OHD) Serum Concentrations in Premature infants: A Preliminary Report L. S. Hillmann, D. V. Huebener and J. G. Haddad Requires Authentication Unlicensed Licensed Download PDF	331
Vitamin D, Calcium and Phosphorus Requirements and Bone Mineralization in Preterm Infants J. J. Steichen, T. L. Gratton, L. Abrams-Becker and R. C. Tsang Requires Authentication Unlicensed Licensed Download PDF	335
The Transplacental Movement of Metabolites of Vitamin D in the Sheep R. Ross, A. D. Care, C. M. Taylor, B. Pelc and B. A. Sommerville Requires Authentication Unlicensed Licensed Download PDF	341
The Effects of Solanum Glaucophyllum Ingestion by Pregnant Cows on Plasma Calcium Levels in Dams, Fetuses and Neonates and on the Mineral Composition of Colostrum J. P. Barlet, R. Roux and M.-J. Davicco Requires Authentication Unlicensed Licensed Download PDF	345
The Vitamin D₃ Requirement for Premature Infants H. Wolf, V. Gräff and G. Offermann Requires Authentication Unlicensed Licensed Download PDF	349
Calcium Uptake and Binding by Membrane Fractions of Human Placenta: ATP Dependent Calcium Accumulation J .A. Whitsett, M. Costello, D. Lo, J. Bohn and R. C. Tsang Requires Authentication Unlicensed Licensed Download PDF	353
Skeletal Actions
Influence of 1,25(OH)₂D₃ on Bone Surface Lining Cells and on cartilage mineralisation in vitro. Ultrastructural studies B. Krempien and F. Klimpel Requires Authentication Unlicensed Licensed Download PDF	359
The Role of Vitamin D Metabolites in Calcification of Chicken Epiphysis A. Ornoy, E. Sekeles, R. Cohen and S. Edelstein Requires Authentication Unlicensed Licensed Download PDF	363
Bone Mineral Solubility and its Alteration by 1,25-Dihydroxyvitamin D₃ R. Brommage and W. F. Neuman Requires Authentication Unlicensed Licensed Download PDF	369
Accelerated Bone Formation in End Stage Renal Disease S. L. Teitelbaum, M. A. Bergfled, J. Freitag and K. A. Hruska Requires Authentication Unlicensed Licensed Download PDF	373
24,25-Dihydroxyvitamin D: The Preferred Metabolite for Bone S. Edelstein and A. Ornoy Requires Authentication Unlicensed Licensed Download PDF	381
Cellular Location and Regulation of the 24,25-Dihydroxyvitamin D₃ Formation in Cultured Cells from Bone and Cartilage M. Carabedian, M. Lieberherr, M. T. Corvol, H. Guiollozo, C. L. Thil and S. Balsan Requires Authentication Unlicensed Licensed Download PDF	391
Comparison of the Histological Effect and Metabolism of 25-(OH)D and 1,25-(OH)₂D in Rat Bone J .A. Gallagher and D. E. M. Lawson Requires Authentication Unlicensed Licensed Download PDF	399
Action of Solanum Malacoxylon on Bone Histology of Vitamin D Deficient Rats M. C. de Vernejoul, M. L. Queille, R. W. Nordin, C. A. Mautalen and L. Miravet Requires Authentication Unlicensed Licensed Download PDF	403
Dual Action of Parathyroid Hormone on the Mineralization of Rat Incisor Dentin S. Matsumoto, T. Tsudzki and M. Yamaguchi Requires Authentication Unlicensed Licensed Download PDF	411
Influence of Diet on the Response of Bone Cells to 1,25-OH)₂D₃ in Thyroparathyroidectomized Rats S. E. Weisbrode, C. C. Capen and A. W. Norman Requires Authentication Unlicensed Licensed Download PDF	415
Nuclear Binding of 24,25-(OH)₂D₃ and its Effect on DNA Polymerase Activities in Cultured Chondrocytes M. T. Corvol, M. F. Dumontier, A. Ulmann, M. Garabedian and G. Witmer Requires Authentication Unlicensed Licensed Download PDF	419
Effects and Interaction of 1,25 (OH)₂Ds and 24,25 (OH)₂D₃ on Bone H. H. Malluche, H. Henry, W. A. Meyer, D. Sherman, S. G. Massry and A. W. Norman Requires Authentication Unlicensed Licensed Download PDF	425
Effects on Mineral Homeostasis of 1,25 (OH)₂D₃ and 24,25 (OH)₂D₃, Alone and in Combination, in Rats B. S. Levine, D. B. N. Lee, N. Brautbar, M. W. Walling, C. R. Kleeman and J. W. Coburn Requires Authentication Unlicensed Licensed Download PDF	429
Effect of Dihydroxylated Vitamin D Metabolites on Experimental Rickets D. Kraft, G. Offermann and R. Steldinger Requires Authentication Unlicensed Licensed Download PDF	431
Evidence for the Presence of 25-OH-D₃ Binding Proteins in Embryonic Cartilage F. Vittur, M. Zanetti, N. Stagni, R. Camerotto and B. de Bernard Requires Authentication Unlicensed Licensed Download PDF	435
Glucocorticoid Dependence of Cytosol 1,25-Dihydroxycholecalciferol Receptors in Fetal Rat Calvaria S. C. Manolagas, D. C. Anderson and G. A. Lumb Requires Authentication Unlicensed Licensed Download PDF	439
Vitamin D Metabolism
Recent Developments in the Metabolism of Vitamin D H. F. De Luca and H. K. Schnoes Requires Authentication Unlicensed Licensed Download PDF	445
The Role of Systemic PH in the Bioactivation of Vitamin D L. V. Avioli Requires Authentication Unlicensed Licensed Download PDF	459
The Site of Synthesis of 1,25(OH)₂ Vitamin D₃ in the Kidney A Microenzymatic Assay on Isolated Tubules M. G. Brunette, M. Chan, C. Ferriere and K. D. Roberts Requires Authentication Unlicensed Licensed Download PDF	463
Response of Chick Kidney Cell Cultures to 1,25-Dihydroxyvitamin D₃ H. E. Henry Requires Authentication Unlicensed Licensed Download PDF	467
Growth Hormone and Prolactin Action on Vitamin D Metabolism in the Rat E. M. Spencer, O. Tobiassen, P. Ling and E. Braunstein Requires Authentication Unlicensed Licensed Download PDF	475
Effective Liver 25-Hydroxylation of Vitamin D under Chronic Ethanol Administration in the Rat M. Gascon, B. Hollis and S. Mah Requires Authentication Unlicensed Licensed Download PDF	479
Calcium Transport by Rat Colon: Response to 1a,25(OH)₂D₃ and Dietary Calcium Restriction M. J. Favus, S. C. Kathpalia and F. L. Coe Requires Authentication Unlicensed Licensed Download PDF	483
Direct Vitamin D3-Metabolite Regulation of Kidney 25-Hydroxyvitamin D₃ Metabolism J. L. Omdahl, L. A. Hunsaker and A. P. Evan Requires Authentication Unlicensed Licensed Download PDF	493
The Regulation of 25-Hydroxylation by Vitamin D Intake in Man: A Theoretical Model A. M. Parfitt, M. Mathews, D. S. Rao and M. Kleerekoper Requires Authentication Unlicensed Licensed Download PDF	497
Minimal Deprivation of Vitamin D Enables Parathyroid Hormone to Stimulate 25-OH Vitamin D - 1a-Hydroxylase B. E. Booth, H. C. Tsai and R. Curtis Morris Requires Authentication Unlicensed Licensed Download PDF	501
Vitamin D Metabolism in Japanese Quail: Effects of Lead Exposure and Dietary Calcium S. N. Baksi and A. D. Kenny Requires Authentication Unlicensed Licensed Download PDF	503
Evidence for a Calcium-Dependent, PTH-lndependent Regulation of Plasma 1,25-Dihydroxyvitamin D in Rats U. Trechsel, J. A. Eismann, J.-P. Bonjour and H. Fleisch Requires Authentication Unlicensed Licensed Download PDF	511
Computer Modeling of Vitamin Metabolism J. L. Omdahl, R. C. Allen and R. P. Eaton Requires Authentication Unlicensed Licensed Download PDF	515
Prolactin, Growth Hormone and Vitamin D Metabolism I. Maclntyre, D. J. Brown and E. Spanos Requires Authentication Unlicensed Licensed Download PDF	523
A Study of the Physiologic Significance of 24-Hydroxylation of 25-Hydroxyvitamin D Y. Tanaka, H. F. DeLuca and N. Ikekawa Requires Authentication Unlicensed Licensed Download PDF	531
Dynamic Aspects of Vitamin D Metabolism: Formation of Hydroxylated Metabolites from A Physiological Dose of Cholecalciferol in Vitamin D Depleted Man S. W. Stanbury Requires Authentication Unlicensed Licensed Download PDF	537
The Regulation of Plasma 1,25-(OH)₂-D Concentrations in Healthy Adults R. W. Gray, J. Lemann and N. D. Adams Requires Authentication Unlicensed Licensed Download PDF	545
The Role of the Liver in the Control of Vitamin D Metabolism E. B. Mawer Requires Authentication Unlicensed Licensed Download PDF	553
Prostaglandins and 25-Hydroxyvitamin D-1a-Hydroxylase J. D. Wark, R. G. Larkins, J. A. Eiman and T. J. Martin Requires Authentication Unlicensed Licensed Download PDF	563
Regulation of Plasma Levels of 1,25 Dihydroxy Vitamin D in Growing Dogs with Thyroparathroidectomy and Varying Amounts of Parathyroid Hormone L. A. Nagode and C. L. Steinmeyer Requires Authentication Unlicensed Licensed Download PDF	567
Both 24R,25-Dihydroxyvitamin D₃ and 1a,25-Dihydroxyvitamin D₃ are Indispensable for Normal Calcium and Phosphorus Homeostasis A. W. Norman and H. L. Henry Requires Authentication Unlicensed Licensed Download PDF	571
New Renal Metabolites of 24,25-Dihydroxyvitamin Ds in the Chick T. Suda, Y. Takasaki and N. Horiuchi Requires Authentication Unlicensed Licensed Download PDF	579
The 1a- and 24-Hydroxylases of 25-Hydroxycholecalciferol: one or two Enzymes? J. G. Ghazarian Requires Authentication Unlicensed Licensed Download PDF	587
Regulation of 25-Hydroxycholecalciferol-1 and -24-Hydroxylases in Cultured Kidney Cells U. Trechsel, J. P. Bonjour and H. Fleisch Requires Authentication Unlicensed Licensed Download PDF	597
Possible Extra-Renal 25-OHD₃-1a-Hydroxylase Activity in the Pregnant Rat G. E. Lester, T. K. Gray and R. S. Lorenc Requires Authentication Unlicensed Licensed Download PDF	605
The Absorption and Metabolism of Vitamin D₃ from Parenteral Injection Sites M. Davies and E. B. Mawer Requires Authentication Unlicensed Licensed Download PDF	609
1,25-(OH)₂ Vitamin D₃ & 24,25-(OH)₂ Vitamin D₃ Synthesis by the Isolated Perfused Rat Kidney A. M. Rosenthal, G. Jones, D. Fraser and S. W. Kooh Requires Authentication Unlicensed Licensed Download PDF	613
In Vitro Regulation of 25-Hydroxyvitamin D₃ Metabolism by Avian Kidney Cells in Serum-Free Medium R. Turner, G. A. Howard, J. I. Rader, B. L. Bottemiller and D. J. Baylink Requires Authentication Unlicensed Licensed Download PDF	617
Comparative Studies on Mitochondrial and Microsomal NADPH-Cytochromec Reductases of Chick Tissues J .A. Kulkoski, J. L. Weber, J. E. Martinez and J. G. Ghazarian Requires Authentication Unlicensed Licensed Download PDF	621
Effect of Pregnancy, Acromegaly, Primary Hyperparathyroidism and Prolactinoma on 1,25-Dihydroxyvitamin D in Man D. J. Brown, E. Spanos, P. Raptis and I. Maclntyre Requires Authentication Unlicensed Licensed Download PDF	625
Relationship of Dietary Phosphorus Restriction to Calcium Absorption and Vitamin D Metabolism A. Bar and S. Hurwitz Requires Authentication Unlicensed Licensed Download PDF	629
Intestinal Actions and Calcium Binding Protein: Meaning of Non-Parallel 1,25-Dihydroxycholecalciferol Mediated
Response Relationship in Intestine and Bone to Dose and Time D. T. Zolock, R. L. Morrissey and D. D. Bikle Requires Authentication Unlicensed Licensed Download PDF	639
Cytoplasmic Localization of the Calcium Binding Protein in Rat Duodenal Absorptive Cells P. Marche, C. Le Guern and P. Cassier Requires Authentication Unlicensed Licensed Download PDF	643
Visualization of Vitamin D-Dependent Calcium Binding Protein in Chick Intestine by Immuno-Scanning Electron Microscopy S. Moriuchi, S. Yoshizawa, N. Hosoya, S. Noda and K. Kubota Requires Authentication Unlicensed Licensed Download PDF	647
Influence of High Doses of Vitamin D₃ on Broilers and Adult Hens P. Garcia Partida, C. Panizo, F. P. Montana and I. D. Prieto Requires Authentication Unlicensed Licensed Download PDF	651
Purification of the Intestinal Receptor for 1,25-Dihydroxyvitamin D J. W. Pike and M. R. Haussler Requires Authentication Unlicensed Licensed Download PDF	659
Recent Progress on the Application of Affinity and Covalent Chromatography to the Purification of the 1,25-Dihydroxyvitamin D₃ Receptor from Chick Intestinal Mucosa W. R. Wecksler, F. P. Ross, W. H. Okamura and A. W. Norman Requires Authentication Unlicensed Licensed Download PDF	663
1,25-Dihydroxycholecalciferol and the Prevention of Parturient Hypocalcemia and Paresis ("Milk Fever") in Pregnant Dairy Cows C. C. Capen, G. F. Hoffsis and A. W. Norman Requires Authentication Unlicensed Licensed Download PDF	667
A Vitamin D-Induced, Calcium-Binding Protein from Rat Intestinal Brush Border A. Miller, T.-H. Ueng and F. Bronner Requires Authentication Unlicensed Licensed Download PDF	675
Relationship of Intestinal Calcium Absorption to Intestinal and Plasma Calcium Binding Protein Measured by a Radioimmunoassay A. Bar and S. Hurwitz Requires Authentication Unlicensed Licensed Download PDF	679
The Effect of 1,25-Dihydroxycholecalciferol and Hydrocortisone on the Development of the Embryonic Chick Duodenum N. Hosoya, S. Moriuchi, S. Yoshizawa, S. Noda and K. Kubota Requires Authentication Unlicensed Licensed Download PDF	683
Theories on the Mechanism of Action of 1,25(OH)₃D₃ on Active Intestinal Calcium and Inorganic Phosphate Absorption: are the Calcium and Phosphate Transport Processes Coupled, Uncoupled or Both? M. W. Walling and D. B. N. Lee Requires Authentication Unlicensed Licensed Download PDF	687
Fundamental Actions of 1,25 Dihydroxycholecalciferol on Intestinal Ion Transport do not Involve Gene Activation O. Fontaine, T. Matsumoto, M. Simoniescu, D. B. P. Goodman and H. Rasmussen Requires Authentication Unlicensed Licensed Download PDF	693
The Effect of Cholecalciferol on the Phosphorylation of Intestinal Membrane Proteins R. H. Wasserman and M. E. Brindak Requires Authentication Unlicensed Licensed Download PDF	703
Some Biochemical Responses of Chick Intestine to 1,25- Dihydroxyvitamin D D. E. M. Lawson, H. Harding, S. Lane and P. Wilson Requires Authentication Unlicensed Licensed Download PDF	711
Induction of Metallothionein(s) in Organ-Cultured Duodenum: Relationship to 1a,25-(OH)₂D₃-lnduced CaBP Synthesis R. A. Corradino, C. S. Fullmer, E. Frelier and S. Maxwell Requires Authentication Unlicensed Licensed Download PDF	731
Vitamin D and Calcium Absorption: Computer Simulation S. Hurwitz, H. Talpaz and A. Bar Requires Authentication Unlicensed Licensed Download PDF	735
Renal Osteodystrophy
Clinical Assessments of Vitamin D₃ - Therapy in Patients on Longterm Haemodialysis W. Seeger, P. Müller, K. Buchali, I. Grossmann and C. Hansen Requires Authentication Unlicensed Licensed Download PDF	745
Adverse Effects of Vitamin D Metabolites on Osteitis Fibrosa in Patients on Chronic Hemodialysis: Critical Role of Induced Hyperphosphatemia J. L. Sébert, J. F. de Frémont, J. Guéris, B. Coevoet, P. Marie, A. Smadja, D. Kuntz, A. Ryckewaert, P. Meunier and A. Fournier Requires Authentication Unlicensed Licensed Download PDF	751
Assessment of Long-Term Effects of 1a(OH)D₃ on PTH Secretion, Intestinal Calcium Absorption and Bone in Chronic Renal Failure S. Madsen, K. Ølgaard and J. Ladefoged Requires Authentication Unlicensed Licensed Download PDF	755
Hypergonadotropic Hypogonadism in Renal Failure - A Defect Responsive to 1,25(OH)₂D₃ W. Kreusser, U. Spiegelberg and E. Ritz Requires Authentication Unlicensed Licensed Download PDF	763
Comparative Effects of 1,25-Dihydroxycholecalciferol and Cholecalciferol in non-Dialyzed Chronic Renal Failure M. S. Christensen, F. Meisen, C. Christiansen, B. Hartnack, O. Sjo and P. Rodbro Requires Authentication Unlicensed Licensed Download PDF	767
Medium term Effects of 1,25-Dihydroxy-vitamin D in Patients with Renal Osteopathy E. Leicht, G. Biro, H. Baumhöfener and Chr. Blumy Requires Authentication Unlicensed Licensed Download PDF	771
The Early Detection and Treatment of Renal Osteodystrophy P. E. Cordy Requires Authentication Unlicensed Licensed Download PDF	775
The Combined Use of Human Calcitonin and 1,25-Dihydroxycholecalciferol in the Treatment of Renal Osteodystrophy K. Farrington, Z. Varghese and J. F. Moorhead Requires Authentication Unlicensed Licensed Download PDF	781
Intestinal Calcium Transport in Vitro as Influenced by Azotemia, Dietary Calcium, Parathyroidectomy and 1,25-Dihydroxycholecalciferol (1,25-DHCC) Treatment. - Role of Calcium - ATPase H. Schiffl, N. Oswald and U. Binswanger Requires Authentication Unlicensed Licensed Download PDF	787
Recurrence of Hyperparathyroidism from Autografted Parathyroid Fragments in Uremic Patients in Spite of Administration of 25(OH)D₃ and 1a(OH)D₃ T. Drüeke, J. Zingraff, J. Guéris, N. Chkoff and C. Dubost Requires Authentication Unlicensed Licensed Download PDF	791
25 Hydroxycholecalciferol Plasma Levels in Anephric Patients After Oral Loading of Vitamin D D. Brancaccio, G. Coen, C. Galmozzi, S. Casati and G. Lucentini Requires Authentication Unlicensed Licensed Download PDF	795
The Histological Study on Experimental Renal Osteodystrophy in Rats R. Niki, H. Ohkawa, S. Suzuki, Y. Takagaki, M. Fukushima, M. Ono, T. Shimizu, Y. Nishii and T. Suda Requires Authentication Unlicensed Licensed Download PDF	799
Long Term Effects of Small Doses of 1,25 Dihydroxycholecalciferol in Dialysis Patients B. Hochman, V. Gura, G. Boner, A. Weiss, A. J. Olah and J. Rosenfeld Requires Authentication Unlicensed Licensed Download PDF	803
Clinical and Biological Efficiency of 1,25 Dihydrocholecalciferol in Chronic Dialysis Patients with Renal Osteodystrophy R. L. Schmitt, M. A. Dambacher, J. Gunçaga, A. G. Olah, A. Omichi and H. A. Jahn Requires Authentication Unlicensed Licensed Download PDF	807
Histomorphometric Evaluation of the effect of 1,25-DHCC in Type II and III of Renal Bone Disorders G. Delling, H. Lühmann, M. Bulla, Ch. Fuchs, H. V. Henning, J. L. J. Jansen, R. Ziegler and W. Schulz Requires Authentication Unlicensed Licensed Download PDF	811
Histomorphometry of Bone Changes in Renal Osteodystrophy After Treatment with 1,25-Dihydroxycholecalciferol A. J. Olah, H. Jahn, F. W. Reutter, R. König, A. Blumberg and A. Colombi Requires Authentication Unlicensed Licensed Download PDF	817
The use of 5,6-trans-25-OH-Cholecalciferol in the Treatment of Patients with Fully Developed Renal Osteopathy Requiring Dialysis: Therapeutical Application and Treatment Results W. Cremer, N. Graben, H.-G. Grigoleit and P. Merguet Requires Authentication Unlicensed Licensed Download PDF	821
Clinical Experience in Long Term Treatment with 1,25-DHCC in Different Histological Forms of Renal Osteopathy W. Schulz, P. Spiegel and G. Delling Requires Authentication Unlicensed Licensed Download PDF	827
Calcium-Phosphorus Metabolism and Renal Function During 1a-OH-D₃ Vitamin Treatment of Patients with Chronic Renal Disease H. E. Nielsen, M. S. Christensen, F. K. Romer, H. E. Hansen and F. Meisen Requires Authentication Unlicensed Licensed Download PDF	831
Newcastle Bone Disease M. K. Ward, I. S. Parkinson, T. G. Feest, H. A. Ellis and D. N. S. Kerr Requires Authentication Unlicensed Licensed Download PDF	835
The Measurement of 1,25-(OH)₂-D by Competitive Protein Binding Assay in the Plasma of Anephric Patients: The Effects of Dihydrotachysterol Therapy R. W. Gray, N. D. Adams and J. Lemann Requires Authentication Unlicensed Licensed Download PDF	839
25-Hydroxycholecalciferol and 1,25 Dihydroxycholecalciferol in the Treatment of Renal Osteodystrophy G. Coen, M. Taccone Gallucci, E. Bonucci and G. Bianchini Requires Authentication Unlicensed Licensed Download PDF	843
Bone Histomorphometry in Children with Early Chronic Renal Failure Treated with 25 (OH)D₃ R. Baron, M. Norman, A. Mazur, A. Gruskin and H. Rasmussen Requires Authentication Unlicensed Licensed Download PDF	847
Hypercalcemia During Treatment of Uremic Patients with 1,25(OH)₂D₃: Analysis of 43 Cases S. N. Winkler, A. S. Brickman, E. G. C. Wong, D. J. Sherrard, R. B. Miller, C. M. Bennet and J. W. Coburn Requires Authentication Unlicensed Licensed Download PDF	851
Renal Bone Disorder in Children: Therapy with Vitamin D₃ or 1,25- Dihydroxycholecalciferol M. Bulla, G. Delling, G. Offermann, R. Ziegler, G. Benz, H. Luehmann and A. Sanchez de Reutter Requires Authentication Unlicensed Licensed Download PDF	853
Treatment of Predialysis Renal Bone Disease with 1a-(OH) Vitamin D₃ and 1.25-(OH)₂ Vitamin D₃. Initial Results of Balance Studies and the Effect on Intestinal Calcium Absorption, Serum PTH and Calcitonin Levels J. R. Juttmann and J. C. Birkenhager Requires Authentication Unlicensed Licensed Download PDF	861
The Effect of 1-a-OHD₃ on Bone Changes in Non-Dialysed Patients with Chronic Renal Insufficiency F. Meisen, H. E. Nielsen and F. K. Romer Requires Authentication Unlicensed Licensed Download PDF	865
25 Hydroxyvitamin D in Renal Osteodystrophy: Long Term Results of A Six-Center Trial R. R. Recker Requires Authentication Unlicensed Licensed Download PDF	869
Further Therapeutical Experience with the Vitamin D Analog 5,6-trans-25-OHCC in Renal Osteopathy H.-G. Grigoleit, D. Kraft, K. Schaefer, G. Offermann, D. von Herrath and G. Delling Requires Authentication Unlicensed Licensed Download PDF	877
A New Laboratory Model for Renal Osteodystrophy and Vitamin D Y. Nishii, M. Fukushima, T. Shimizu, M. Nanjo, R. Niki, H. Ohkawa, Y. Hinohara, M. Ogawa, Y. Tohira, H. Nakano, K. Okano and T. Suda Requires Authentication Unlicensed Licensed Download PDF	885
The Influence of Uremia, Aluminiumhydroxide and Various Vitamin D Compounds on the Course of Nutritional Rickets in Rats D. von Herrath, K. Schaefer and B. Krempien Requires Authentication Unlicensed Licensed Download PDF	893
Effect of Vitamin D Analogs in Rats with Experimental Renal Osteodystrophy K. Ueno, H. Kawashima, Y. Izawa, N. Ohnuma, T. Makita, S. Kurozumi, Y. Hashimoto, S. Ishimoto, Y. Kawaguchi, M. Yamamoto, Y. Kimura, Y. Ogura, Y. Ueda, K. Kushida and T. Inoue Requires Authentication Unlicensed Licensed Download PDF	901
Evaluation of Histological Procedures in the Investigation of Bone Disease Related to Vitamin D E. Ritz, B. Krempien and H. H. Malluche Requires Authentication Unlicensed Licensed Download PDF	907
Pathophysiology of Vitamin D Related Diseases
Effects of in Vitro and in Vivo Sodium Restriction on Corticosteroidinduced Intestinal Calcium Malabsorption J. S. Adams and B. P. Lukert Requires Authentication Unlicensed Licensed Download PDF	915
Trisetum Calcinosis: Current Status of Clinical Research G. Dirksen Requires Authentication Unlicensed Licensed Download PDF	921
X-Linked Hypophosphatemia is a Disorder of Phosphate Transport in the Renal Brush Border Membrane in the Hypophosphatemic Mouse. Why is Serum 1,25-(OH)₂D Low in the Human Homologue? H. S. Tenenhouse, C. R. Scriver and H. F. De Luca Requires Authentication Unlicensed Licensed Download PDF	925
The Effect of Vitamin D₃ and Metabolites on Magnesium Metabolism B. S. Levine, N. Brautbar, D. B. N. Lee, M. W. Walling, K. Kurokawa, C. R. Kleeman and J. W. Coburn Requires Authentication Unlicensed Licensed Download PDF	933
Subnormal Serum 1,25-Dihydroxyvitamin D₃ Levels in Children with Glomerular Disease Receiving Corticosteroids R. W. Chesney, R. B. Mazess, A. J. Hamstra, S. O’Regan and H. F. De Luca Requires Authentication Unlicensed Licensed Download PDF	935
Regulation of Serum Phosphorus by 1,25(OH)₂D₃ D. B. N. Lee, B. S. Levine, M. W. Walling, N. Brautbar, R. K. Lessman, V. Silis and J. W. Coburn Requires Authentication Unlicensed Licensed Download PDF	939
Unexplained hypercalcemia:? Sarcoidosis sine Sarcoidosis: with Elevated Serum Level of 1,25 DHCC B. Frame and A. M. Parfitt Requires Authentication Unlicensed Licensed Download PDF	941
Vitamin D Metabolites in Hypercalcitoninemic States R. Ziegler, F. Raue, M. Grossmann and H. Schmidt-Gayk Requires Authentication Unlicensed Licensed Download PDF	945
Target Cell Resistance in Pseudohypoparathyroidism: Single or Multiple? A. M. Parfitt Requires Authentication Unlicensed Licensed Download PDF	949
Vitamin D Metabolism In Patients with Nephrolithiasis J. Lemann, R. W. Gray and N. D. Adams Requires Authentication Unlicensed Licensed Download PDF	957
Evidence for Abnormal Metabolism of Vitamin D in Sarcoidosis N. H. Bell Requires Authentication Unlicensed Licensed Download PDF	963
Effects of Experimental Diabetes in the Rat on Calcium Transport and Vitamin D Metabolism H. P. Schedl Requires Authentication Unlicensed Licensed Download PDF	967
Absorption of Vitamin D and 25-OH Vitamin D in patients with Intestinal Malabsorption E. L. Krawitt, E. B. Mawer and M. Davies Requires Authentication Unlicensed Licensed Download PDF	975
Effect of Diabetes in Rats on the Metabolism of Cholecalciferol and 25-Hydroxycholecalciferol S. Sulimovici and M. A. Roginsky Requires Authentication Unlicensed Licensed Download PDF	979
Do Alkaline Phosphatases Have a Physiological Function? S. Posen Requires Authentication Unlicensed Licensed Download PDF	983
Clinical Application of the 1,25-(OH)₂D Assay B. Lund, O. H. Sorensen and B. Lund Requires Authentication Unlicensed Licensed Download PDF	991
Elevated Plasma 1,25-(OH)₂D Following Massive Dosing of Vitamin D₃ in Dairy Cattle R. L. Horst and E. T. Littledike Requires Authentication Unlicensed Licensed Download PDF	999
Vitamin D Metabolism in the Diabetic Rat R. L. Horst, S. L. Spoede and E. T. Littledike Requires Authentication Unlicensed Licensed Download PDF	1003
The Effect of Chronic Excess or Deficiency of Growth Hormone on Plasma 1,25-Dihydroxyvitamin D Levels in man R. Kumar, T. J. Merimee, P. Silva and F. H. Epstein Requires Authentication Unlicensed Licensed Download PDF	1005
25-Hydroxylation of Vitamin D in the Elderly R. K. Skinner Requires Authentication Unlicensed Licensed Download PDF	1011
Intestinal Absorption of Radiophosphate After Physiological Doses of 1,25-Dihydroxyvitamin D in Normals and Pathological Conditions A. Caniggia and A. Vattimo Requires Authentication Unlicensed Licensed Download PDF	1015
Calcium Metabolism Following Proximal Gastric Vagotomy in Man D. Scholz, P. O. Schwüle, W. Engelhardt and C. Morcinietz Requires Authentication Unlicensed Licensed Download PDF	1019
25-Hydroxyvitamin D Metabolism in Nontropical Sprue S. B. Arnaud, A. D. Newcomer, K. P. Offord and V. L. W. Go Requires Authentication Unlicensed Licensed Download PDF	1023
Circulating Vitamin D Metabolites in A Hypoparathyroid Patient Resistent to Vitamin D E. Keck and H. V. Lilienfeld-Toal Requires Authentication Unlicensed Licensed Download PDF	1027
The Ability of 1a, 25-Dihydroxycholecalciferol to Alter the Fatty Acid Composition of Phosphoglycerides in Rat Intestinal Mucosa and Smooth Muscle W. Alastair, M. Hay, A. G. Hassam, M. A. Crawford, P. Stevens, E. B. Mawer and Ch. Case Requires Authentication Unlicensed Licensed Download PDF	1031
Vitamin D Dependent Clinical Disorders - Bone Disease : Clinical Aspects - Unanswered Questions in Renal Osteodystrophy - Problems of Vitamin D Nomenclature - Addendum Requires Authentication Unlicensed Licensed Download PDF	1035
Author Index Requires Authentication Unlicensed Licensed Download PDF	1261
Subject Index Requires Authentication Unlicensed Licensed Download PDF	1273
Backmatter Requires Authentication Unlicensed Licensed Download PDF	1319

Language: English
Publisher: De Gruyter
Copyright year: 1979
Edition: Reprint 2020
Audience: College/higher education;
Pages
- Front matter: 26
- Main content: 1318
Illustrations
- Other: Num. figs.
Keywords: Medizin; Vitamin

eBook

Published: October 26, 2020
ISBN: 9783112330029

Hardcover

Published: December 31, 1979
ISBN: 9783112330012