Vitamin B12: Proceedings of the 3rd European Symposium on Vitamin B12 and Intrinsic Factor, University of Zurich, March 5–8, 1979, Zurich, Switzerland

Published by De Gruyter 1979

Vitamin B12

Proceedings of the 3rd European Symposium on Vitamin B12 and Intrinsic Factor, University of Zurich, March 5–8, 1979, Zurich, Switzerland

Edited by: B. Zagalak , W. Friedrich , 1979, Zürich> European Symposium on Vitamin B 12 and Intrinsic Factor <3 and Universität <Zürich>

https://doi.org/10.1515/9783111510828

Contents

Frontmatter Publicly Available Download PDF	I
Preface Publicly Available Download PDF	VII
CONTENTS Publicly Available Download PDF	IX
Chapter 1. CHEMISTRY OF CORRINOIDS. TOTAL SYNTHESIS OF VITAMIN B₁₂
Introductory remarks for opening of 3rd European Symposium on vitamin B₁₂ Lord Todd, O. M. and P. R. S. Requires Authentication Unlicensed Licensed Download PDF	1
Introductory remarks. Historical perspectives on the isolation of crystalline vitamin B₁₂ K. Folkers Requires Authentication Unlicensed Licensed Download PDF	7
New and old problems in the structure analysis of vitamin B₁₂ Dorothy Crowfoot Hodgkin Requires Authentication Unlicensed Licensed Download PDF	19
Synthetic vitamin B₁₂ R. B. Woodward Requires Authentication Unlicensed Licensed Download PDF	37
Chemical synthesis of corrinoids: current problems and recent advances A. Eschenmoser Requires Authentication Unlicensed Licensed Download PDF	89
Recent studies on the synthesis of vitamin B₁₂ R. V. Stevens Requires Authentication Unlicensed Licensed Download PDF	119
New reactions of the chromophoric system of vitamin B₁₂ derivatives H. H. Inhoffen Requires Authentication Unlicensed Licensed Download PDF	137
Structure and reactivity of the so-called stable yellow corrinoids B. Grüning and A. Gossauer Requires Authentication Unlicensed Licensed Download PDF	141
Concerning the structure of so-called yellow products obtained from naturally occurring metal-free corrinoids G. Schlingmann and V. B. Koppenhagen Requires Authentication Unlicensed Licensed Download PDF	149
Correlation of vitamin B₁₂ methanolysis products with cobyrinic methyl ester amides prepared from hydrogenobyrinic acid amides G. Schlingmann, B. Dresow, L. Ernst and V. B. Koppenhagen Requires Authentication Unlicensed Licensed Download PDF	155
Preparation and X-ray structural analyses of a cobyrinic acid diamide and the corresponding rhodium analogue B. Dresow, V. B. Koppenhagen and W. S. Sheldrick Requires Authentication Unlicensed Licensed Download PDF	159
Concerning a new corrinoid from municipal sludge W. Friedrich Requires Authentication Unlicensed Licensed Download PDF	163
Steric course of the substitution by vitamin B_12s as studied by ¹H-NMR spectroscopy M. Fountoulakis and J. Rétey Requires Authentication Unlicensed Licensed Download PDF	169
Synthesis and X-ray analysis of a porphyrin-type Co(I)-complex P. Engel, G. Rytz, L. Walder, U. Vögeli and R. Scheffold Requires Authentication Unlicensed Licensed Download PDF	171
Stereochemistry of the formation and cleavage of the Co-C bond in a vitamin B₁₂ model G. Rytz, L. Walder and R. Scheffold Requires Authentication Unlicensed Licensed Download PDF	173
The structure of superoxocobalamin, a single crystal ESR study E. Jörin, A. Schweiger and Hs. H. Günthard Requires Authentication Unlicensed Licensed Download PDF	175
NMR studies of a novel form of vitamin B₁₂ R. K. Gupta, P. C. Goswami and A. Nath Requires Authentication Unlicensed Licensed Download PDF	179
Circular dichroism study of organocobalamins I. P. Rudakova, T. A. Pospelova, E. M. Tachkova and A. M. Yurkevich Requires Authentication Unlicensed Licensed Download PDF	183
Concerning electronic, CD and ORD spectra of isomeric pairs of several (Co-methyl)-corrinoids M. Moskophidis Requires Authentication Unlicensed Licensed Download PDF	189
Some properties of cobalaminhexacyanoferrate Y. Popova and S. Angelova Requires Authentication Unlicensed Licensed Download PDF	193
Temperature-jump kinetics of the "base-on" - "base-off" equilibrium of methylcobalamin K. L. Brown, A. W. Awtrey, P. B. Chock and S. G. Rhee Requires Authentication Unlicensed Licensed Download PDF	199
Electrochemistry of vitamin B₁₂. Equilibria, kinetics and mechanisms in the B_12a - B_12r - B_12s oxido-reduction J. M. Savéant, N. de Tacconi, D. Lexa and J. Zickler Requires Authentication Unlicensed Licensed Download PDF	203
Electrochemistry of vitamin B₁₂. Alkyl cobalamins and cobinamides D. Lexa, J. M. Savéant and J. P. Soufflet Requires Authentication Unlicensed Licensed Download PDF	213
Chapter 2. BIOSYNTHESIS OF CORRINOIDS
Recent biosynthetic researches on vitamin B₁₂ A. R. Battersby Requires Authentication Unlicensed Licensed Download PDF	217
Intermediary metabolism of cobyrinic acid biosynthesis A. I. Scott Requires Authentication Unlicensed Licensed Download PDF	247
On the methylation process in cobyrinic acid biosynthesis G. Müller, R. Deeg, K. D. Gneuß, G. Gunzer and H. -P. Kriemler Requires Authentication Unlicensed Licensed Download PDF	279
Biogenesis of tetrapyrrole compounds (porphyrins and corrinoids), and its regulation V. Ya. Bykhovsky Requires Authentication Unlicensed Licensed Download PDF	293
Factor I ex Clostridium tetanomorphum: proof of structure and relationship to vitamin B₁₂ biosynthesis M. Imfeld, D. Arigoni, R. Deeg and G. Müller Requires Authentication Unlicensed Licensed Download PDF	315
On the biosynthesis of the 5,6-dimethylbenzimidazole moiety of vitamin B₁₂ P. Renz, J. Hörig and R. Wurm Requires Authentication Unlicensed Licensed Download PDF	317
The enzyme system of propionic acid bacteria transforming riboflavin into 5,6-dimethylbenzimidazole J. Hörig and P. Renz Requires Authentication Unlicensed Licensed Download PDF	323
Straight approaches to the nucleotide loop H. C. Friedmann Requires Authentication Unlicensed Licensed Download PDF	331
Ribosomal proteins share in vitamin B₁₂ biosynthesis W. Walerych and E. Pezacka Requires Authentication Unlicensed Licensed Download PDF	345
The ribosomal proteins L2, L5, L18 and L25 involved in vitamin B₁₂ biosynthesis E. Pezacka and W. Walerych Requires Authentication Unlicensed Licensed Download PDF	359
Formation and role of vitamin B₁₂ in Protaminobacter ruber and Rhizobium meliloti K. Sato, S. Inukai, S. Ueda, T. Seki and S. Shimizu Requires Authentication Unlicensed Licensed Download PDF	361
Chapter 3. CORRINOID DEPENDENT ENZYMES AND REACTIONS. MODEL SYSTEMS
Current status of the mechanism of action of B₁₂ - coenzyme R. H. Abeles Requires Authentication Unlicensed Licensed Download PDF	373
A stereochemical approach to the diol dehydratase reaction D. Arigoni Requires Authentication Unlicensed Licensed Download PDF	389
Coenzyme B₁₂-dependent diol dehydratase - distribution and metabolic role in Enterobacteriaceae, enzymological properties and interaction with coenzyme B₁₂ Saburo Fukui and Tetsuo Toraya Requires Authentication Unlicensed Licensed Download PDF	413
Adenosylcobalamin-dependent glycerol dehydratase interaction with substrates and their analogs A. A. Poznanskaya and T. L. Korsova Requires Authentication Unlicensed Licensed Download PDF	431
Glycerol dehydratase from Aerobacter aerogenes B. Zagalak Requires Authentication Unlicensed Licensed Download PDF	437
The mechanism of action of methylmalonyl-CoA mutase as studied with isotope labelling and synthetic models J. Rétey Requires Authentication Unlicensed Licensed Download PDF	439
Recent studies on the mechanism of action of ethanolamine ammonia-lyase Bernard M. Babior Requires Authentication Unlicensed Licensed Download PDF	461
Studies on the mechanism of reactions catalysed by ethanolamine ammonia-lyase M. R. Hollaway, H. A. White, K. N. Joblin, A. W. Johnson, M. F. Lappert and O. C. Wallis Requires Authentication Unlicensed Licensed Download PDF	471
Steric course of the ethanolamine-ammonia lyase reaction P. Diziol, H. Haas, J. Rétey, S. Graves and B. M. Babior Requires Authentication Unlicensed Licensed Download PDF	485
The chemical synthesis and coenzymatic properties of analogs of adenosylcobalamin in the ribonucleotide reductase reaction H. P. C. Hogenkamp Requires Authentication Unlicensed Licensed Download PDF	489
Review of the EPR of B_12r and B₁₂ -dependent enzyme reactions John R. Pilbrow Requires Authentication Unlicensed Licensed Download PDF	505
Vitamin B₁₂: current problems and recent advances G. N. Schrauzer, J. H. Grate, M. Hashimoto and A. Maihub Requires Authentication Unlicensed Licensed Download PDF	511
The role of corrinoids in the total synthesis of acetate from C0₂ Harland G. Wood Requires Authentication Unlicensed Licensed Download PDF	529
Mechanisms for B₁₂ -dependent methylation J. M. Wood and Y.-T. Fanchiang Requires Authentication Unlicensed Licensed Download PDF	539
Nonenzymic models for the enigmatic coenzyme B₁₂-dependent carbon-skeleton rearrangements Paul Dowd Requires Authentication Unlicensed Licensed Download PDF	557
The mechanism of action of coenzyme B₁₂ D. Dolphin, A. R. Banks, W. R. Cullen, A. R. Cutler and R. B. Silverman Requires Authentication Unlicensed Licensed Download PDF	575
Model systems for adenosylcobalamin dependent enzymic reactions M. P. Atkins, B. T. Golding and P. J. Sellars Requires Authentication Unlicensed Licensed Download PDF	587
Bridged cobaloximes as vitamin B₁₂ models J. A. Robinson Requires Authentication Unlicensed Licensed Download PDF	599
Modified adenosylaobalamin: model systems for the active sites of corrinoid-dependent enzymes D. L. Anton and H. P. C. Hogenkamp Requires Authentication Unlicensed Licensed Download PDF	605
Chapter 4. ANALOGUES AND ANTAGONISTS OF VITAMIN B₁₂
Naturally occurring vitamin B₁₂ antagonists and their potential therapeutic value D. Perlman, K. L. Perlman, T. H. Williams, U. Schömer and Y. Izumi Requires Authentication Unlicensed Licensed Download PDF	609
Structures of some vitamin B₁₂ analogues and their biological as well as biochemical functions T. Kamikubo and M. Hayashi Requires Authentication Unlicensed Licensed Download PDF	625
Novel metal-free corrinoids and metal analogues V. B. Koppenhagen, E. Warmuth, G. Schlingmann and B. Dresow Requires Authentication Unlicensed Licensed Download PDF	635
Preparation of ferribalamin, the Fe(III)-analogue of vitamin B₁₂ R. Bieganowski and W. Friedrich Requires Authentication Unlicensed Licensed Download PDF	647
Chapter 5. VITAMIN B₁₂ ASSAY
Vitamin B₁₂ assay: an evaluation of radiodilution assay using cobinamide to increase specificity B. A. Cooper, J. Peyman, Erika Jonas and V. M. Whitehead Requires Authentication Unlicensed Licensed Download PDF	649
Effect of residual extract products and the type of binders (R or IF) on serum vitamin B₁₂ levels by radioisotope dilution assay A. Begley and Charles A. Hall Requires Authentication Unlicensed Licensed Download PDF	655
Differential assay of cobamides in serum using R-protein radioisotopic dilution assay, E.coli and E.gracilis assays N. A. Sourial and D. L. Mollin Requires Authentication Unlicensed Licensed Download PDF	657
Rapid determination of corrinoids by high performance liquid chromatography D. Jacobsen, R. Green and M. Savage Requires Authentication Unlicensed Licensed Download PDF	663
Determination of the plasma cobalamins by one-dimensional thin-layer chromatography P. Gimsing, E. Hippe and Ebba Nexø Requires Authentication Unlicensed Licensed Download PDF	665
Chemical quantitation of corrinoids B. Zagalak Requires Authentication Unlicensed Licensed Download PDF	671
Enzymatic estimation of vitamin B₁₂ Zenon Schneider Requires Authentication Unlicensed Licensed Download PDF	673
Essential prerequisites for the analysis of cyanocobalamin in biochemically complex samples using radiometric competitive binding assays R. A. Beck Requires Authentication Unlicensed Licensed Download PDF	675
Chapter 6. ABSORPTION, TRANSPORT AND DISTRIBUTION OF VITAMIN B₁₂
Distribution of cobalamins in the animal body D. M. Matthews Requires Authentication Unlicensed Licensed Download PDF	681
Vitamin B₁₂ in membrane mimetic agents - theoretical considerations and practical applications Janos H. Fendler Requires Authentication Unlicensed Licensed Download PDF	695
Transport of vitamin B₁₂ in Escherichia coli Clive Bradbeer Requires Authentication Unlicensed Licensed Download PDF	711
The plasma transport of cobalamin (Cbl) Charles A. Hall Requires Authentication Unlicensed Licensed Download PDF	725
Soluble and membrane-bound vitamin B₁₂ transport proteins R. Gräsbeck Requires Authentication Unlicensed Licensed Download PDF	743
The origin and clinical implications of vitamin B₁₂ binders - the transcobalamins B. Rachmilewitz, M. Schlesinger, R. Rabinowitz and M. Rachmilewitz Requires Authentication Unlicensed Licensed Download PDF	765
Large vitamin B₁₂-binding proteins and complexes in human serum Ralph Carmel Requires Authentication Unlicensed Licensed Download PDF	777
Heterogeneity of antibodies against B₁₂ binders in pernicious anaemia J. P. Nicolas Requires Authentication Unlicensed Licensed Download PDF	791
The intraluminal phase of vitamin B₁₂ transport in humans Y. Parmentier, G. Marcoullis, J. P. Nicolas and M. O. Perrin Requires Authentication Unlicensed Licensed Download PDF	803
Polymorphic variants of transcobalamin II rare alleles in family studies Marijke Fràter-Schröder, R. Osusky, W. H. Hitzig, R. Bütler and Aila Hasler-Häkkinen Requires Authentication Unlicensed Licensed Download PDF	807
Relationship between cobalophilin releasing and functional state of polymorphonuclear granulocytes W. Fenrych, J. Hansz, K. Boduch and B. Pytlak Requires Authentication Unlicensed Licensed Download PDF	813
The significance of vitamin B₁₂ binders in the central nervous system M. Inada, M. Kameyama and M. Toyoshima Requires Authentication Unlicensed Licensed Download PDF	821
In vitro acid dissociation of cobalamin-transcobalamin II complexes formed in vivo: a probe in the study of TC II-kinetics H. Gilbert Requires Authentication Unlicensed Licensed Download PDF	827
Calcium dependencies in the binding of transcobalamins to subcellular particles of liver cells Carter M. Becker and William S. Beck Requires Authentication Unlicensed Licensed Download PDF	833
The effect of antibiotics on transcobalamin II synthesis in rabbit liver cell culture C. H. Tan and T. J. Broekelmann Requires Authentication Unlicensed Licensed Download PDF	837
Solubilization and characterization of the transcobalamin II acceptor from human placenta and rabbit liver Ebba Nexø, M. D. Hollenberg and H. Olesen Requires Authentication Unlicensed Licensed Download PDF	843
Strength of binding of methyl-, 5 '-deoxyadenosyl-, cyano- and hydroxocobalamin to human transcobalamin I and II and intrinsic factor Ebba Nexø, H. Olesen and Marianne R. Hansen Requires Authentication Unlicensed Licensed Download PDF	851
Adsorptive endocytosis of transcobalamin II-vitamin B₁₂ by isolated rat liver parenchymal cells J. Lindemans, J. van Kapel and J. Abels Requires Authentication Unlicensed Licensed Download PDF	855
Species specificity between TC II, TC II-Cbl uptake and anti-TC II Mary Haus, Pamela D. Green and Charles A. Hall Requires Authentication Unlicensed Licensed Download PDF	861
Transcobalamin II polymorphism in african populations H. J. Porck, M. Frater-Schröder and A. K. Häkkinen Requires Authentication Unlicensed Licensed Download PDF	863
Transcobalamins during induction of nutritional cobalamin deficiency in the fruit bat R. Green, P. Myers and D. Jacobsen Requires Authentication Unlicensed Licensed Download PDF	867
Heterogeneity of transcobalamin II demonstrated by isoelectric focusing in urea U.-H. Stenman and E. -M. Salonen Requires Authentication Unlicensed Licensed Download PDF	873
Radioimmunosorbent determinations of unsaturated and total transcobalamin II in human serum Marijke Fràter-Schröder, P. Vitins and W. H. Hitzig Requires Authentication Unlicensed Licensed Download PDF	877
The "dU suppression test" and "thymidine suppression test": evidence for reciprocal relationship between the "de novo" and "salvage" pathways of DNA synthesis K. C. Das and V. Herbert Requires Authentication Unlicensed Licensed Download PDF	881
TC II deficiency: observations with deoxyuridine suppression test J. F. Burman, P. N. Malleson, N. A. Sourial and D. L. Mollin Requires Authentication Unlicensed Licensed Download PDF	889
Spectral studies on hog intrinsic factor and hog non-intrinsic factor Ebba Nexø, H. Olesen and Marianne R. Hansen Requires Authentication Unlicensed Licensed Download PDF	895
Amino terminal sequence of hog non-intrinsic factor and hog intrinsic factor D. Bucher, J. Thomsen, H. Olesen and Ebba Nexø Requires Authentication Unlicensed Licensed Download PDF	905
Subunit structure of the pig ileal intrinsic factor receptor Ilkka Kouvonen and Ralph Gräsbeck Requires Authentication Unlicensed Licensed Download PDF	909
Cobinamide blocking assay for intrinsic factor James A. Begley, Alan Trachtenberg and Charles A. Hall Requires Authentication Unlicensed Licensed Download PDF	917
Intracelular transport of vitamin B₁₂ in enterocytes M. Inada, M. Toyoshima and M. Kameyama Requires Authentication Unlicensed Licensed Download PDF	919
Evidence for the chief cell as the source of intrinsic factor secretion in the rat P. C. Sharpe and M. A. Horton Requires Authentication Unlicensed Licensed Download PDF	921
Long-term treatment of pernicious anemia patients with intrinsic factor E. Hauptmann Requires Authentication Unlicensed Licensed Download PDF	929
An analogy of cobalamin membrane transport: an intestinal receptor for heme R. Gräsbeck, I. Kouvonen, Margaretha Lundberg, R. Tenhunen and Hannele Yki-Järvinen Requires Authentication Unlicensed Licensed Download PDF	933
A simplified method for quantitative determination of vitamin B₁₂ absorption E. Hippe, P. Gimsing and N. H. Holländer Requires Authentication Unlicensed Licensed Download PDF	939
Vitamin B₁₂ absorption studies with plastic whole body counter in patients with gastroenterological operation R. Morishita and H. Uchino Requires Authentication Unlicensed Licensed Download PDF	945
Affinity photo-release purification of cobalamin-binding proteins D. Jacobsen and Y. Montejano Requires Authentication Unlicensed Licensed Download PDF	949
Effect of pentagastrin in vitamin B₁₂ absorption in the guinea pig M. Katz and E. Stopa Requires Authentication Unlicensed Licensed Download PDF	955
Synthesis of cobalamin coenzymes in the rat and their secretion from the liver into plasma and bile W. G. E. Cooksley, J. A. Owens, J. C. Linnell, H. A. Hussein, J. M. England and A. S. Tavill Requires Authentication Unlicensed Licensed Download PDF	961
The pattern of cobalamins in human erythrocytes Ebba Nexø and P. Gimsing Requires Authentication Unlicensed Licensed Download PDF	967
Presence of sulfitocobalamin in cell extracts. Resolution and identification by SP-Sephadex C-25 cation exchange chromatography James A. Begley and Charles A. Hall Requires Authentication Unlicensed Licensed Download PDF	971
Mitochondrial cobalamins: types, sources, and functions with evidence of their noninvolvement in mitochondrial DNA synthesis William S. Beck, Raphael Cohen and Jens Jorgensen Requires Authentication Unlicensed Licensed Download PDF	975
Chapter 7. PHYSIOLOGY AND PATHOLOGY OF VITAMIN B₁₂
Studies on vitamin B₁₂ and ubiquinone K. Folkers, J. Y. Choe, Y. Z. Kwen, S. Shizukuishi and S. Nishii Requires Authentication Unlicensed Licensed Download PDF	979
Haematological aspects of cobalamin deficiency J. M. England and J. C. Linnell Requires Authentication Unlicensed Licensed Download PDF	991
The neurology of vitamin B₁₂ deficiency E. H. Reynolds Requires Authentication Unlicensed Licensed Download PDF	1001
Clinioal diseases related to defioienoies of vitamin B₁₂ transport proteins W. H. Hitzig, Marijke Fràter-Schröder and R. Seger Requires Authentication Unlicensed Licensed Download PDF	1009
Effects of methylaobalamin on peripheral neuropathies or experimentally-induced neuropathies M. Inada, M. Ogawa, H. Kameyama and F. Udaka Requires Authentication Unlicensed Licensed Download PDF	1017
Inherited deficiencies of the deoxyadenosylcobalamin (Ado-Cbl) dependent L-methylmalonyl-CoA mutase system: clinical and biochemical aspects R. Baumgartner and H. Wick Requires Authentication Unlicensed Licensed Download PDF	1019
An investigation of a possible role for coenzyme B₁₂ in ribonucleotide reduction in rabbit bone marrow Sarah Hopper Requires Authentication Unlicensed Licensed Download PDF	1025
Participation of cAMP in regulation of coenzyme B₁₂ dependent glycerol dehydratase synthesis from Klebsiella pneumoniae ATCC 85955 A. Stroinski Requires Authentication Unlicensed Licensed Download PDF	1029
Carbon monoxide oxidation by Clostridia: evidence for the involvement of a corrinoid-like compound G. B. Diekert, E. G. Graf and R. K. Thauer Requires Authentication Unlicensed Licensed Download PDF	1033
The in vivo effects of nitrous oxide on human bone marrow - a morphological, biochemical and cell cycle study J. A. L. Amess, J. F. Burman, M. H. Cullen and D. L. Mollin Requires Authentication Unlicensed Licensed Download PDF	1037
Interconversion of cobalamins in human lymphocytes in vitro and the influence of nitrous oxide on synthesis of cobalamin coenzymes E. V. Quadros, Beverley Jackson, A. V. Hoffbrand and J. C. Linnell Requires Authentication Unlicensed Licensed Download PDF	1045
Studies on cobalamin and folate metabolism in rats exposed to nitrous oxide (N₂O) Rosemary Deacon, M. Lumb, M. Muir, Janet Perry, I. Chanarin, Barbara Minty, M. J. Halsey and J. F. Nunn Requires Authentication Unlicensed Licensed Download PDF	1055
Alterations in mammalian cells induced by inactivation of vitamin B₁₂ with nitrous oxide B. Reed, J. Dinn, S. McCann, P. Wilson, H. O’Sullivan, D. G. Weir and J. M. Scott Requires Authentication Unlicensed Licensed Download PDF	1061
High ascorbic acid intake and vitamin B₁₂ status in the rat Shirley Warnock Thenen Requires Authentication Unlicensed Licensed Download PDF	1065
Ability of megadoses of vitamin C to destroy vitamin B₁₂ and cobinamide and to reduce absorption of vitamin B₁₂ (with a note on B₁₂ radioassays) V. Herbert, L. Landau, R. Bash, S. Grosberg and N. Colman Requires Authentication Unlicensed Licensed Download PDF	1069
Interaction between methylcobalamin and some amino acids in single cell proteins J. Skupin, K. Waliszewski and B. Jaszewski Requires Authentication Unlicensed Licensed Download PDF	1079
Methylcobalamin and the modification of proteins in vitro S. J. Kanopkaite, J. A. Rackus, V. R. Kalnev and V. A. Stankevicius Requires Authentication Unlicensed Licensed Download PDF	1085
Deoxyadenosylcobalamin and the process of methylation of tRNA in model systems L. E. Taraseviciene and S. J. Kanopkaite Requires Authentication Unlicensed Licensed Download PDF	1091
The participation of coenzyme B₁₂ in the synthesis of DNA by Propionibacterium shermanii E. P. Jordan, N. V. Antoshkina and L. I. Vorobjeva Requires Authentication Unlicensed Licensed Download PDF	1095
Recent advances in cobalamin metabolism: abnormalities in coenzyme distribution in tumor development and in inherited metabolic disease J. C. Linnell and D. M. Matthews Requires Authentication Unlicensed Licensed Download PDF	1101
On some properties of the effect and metabolism of different cobalamins in tumor-bearing rats G. R. Brazenas, V. V. Bartkeviciene, A. M. Aleksiene, A. J. Alioniene, S. J. Kanopkaite and V. F. Zovyte Requires Authentication Unlicensed Licensed Download PDF	1113
Gastric cancer as a risk factor in pernicious anaemia L. Elsborg and J. Mosbech Requires Authentication Unlicensed Licensed Download PDF	1119
Interference with cobalamin metabolism and tumour growth by an analogue of methylcobalamin N. V. Myasishcheva, E. V. Quadros, Y. V. Vares and J. C. Linnell Requires Authentication Unlicensed Licensed Download PDF	1125
Vitamin B₁₂ requirement for replication of mouse leukemia L1210 cells: functional relevance to folate metabolism Katsuhiko Fujii, Tomohisa Nagasaki and F. M. Huennekens Requires Authentication Unlicensed Licensed Download PDF	1127
Vitamin B₁₂ and folia acid interrelations: a new look F. I. Haurani Requires Authentication Unlicensed Licensed Download PDF	1131
The effect of hypothyroidism on histidine oxidation and folate-dependent enzyme levels E. L. R. Stokstad, Margaret May-Sheng Chan, J. E. Watson, T. Brody and L. Jaenicke Requires Authentication Unlicensed Licensed Download PDF	1139
Cobalamin-dependent methionine synthesis and the regulation of the metabolism of activated folic acid derivatives in cultured human lymphoblasts H. Sauer Requires Authentication Unlicensed Licensed Download PDF	1145
Author and Citation Index Requires Authentication Unlicensed Licensed Download PDF	1149
Subject Index Requires Authentication Unlicensed Licensed Download PDF	1171
Collection of Photographs from the Symposium Requires Authentication Unlicensed Licensed Download PDF	1213

Language: English
Publisher: De Gruyter
Copyright year: 1979
Edition: Reprint 2019
Pages
- Front matter: 17
- Main content: 1212
Illustrations
- Other: Num. figs.
Keywords: Vitamin B12; Woodward, Robert Burns; Corrinoide

eBook

Published: October 8, 2019
ISBN: 9783111510828

Hardcover

Published: April 1, 1979
ISBN: 9783110076684