17. Prague, Czechoslovakia, August 29–September 3, 1982

Published by De Gruyter 1983

17. Prague, Czechoslovakia, August 29–September 3, 1982

Edited by: Karel Bláha and Petr Maloň

Part of the multi-volume work Peptides

https://doi.org/10.1515/9783111694344

Contents

Frontmatter Publicly Available Download PDF	I
Preface Publicly Available Download PDF	V
Contents Publicly Available Download PDF	VII
European Peptide Committee and Programme Committee Publicly Available Download PDF	XXVII
Honorary Committee and Organizing Committee Publicly Available Download PDF	XXVIII
Previous European Peptide Symposia Publicly Available Download PDF	XXIX
List of Participants Publicly Available Download PDF	XXXI
In Memoriam, Emil Taschner Publicly Available Download PDF	XLIII
In Memoriam, Dieter Marquarding Publicly Available Download PDF	XLVII
In Memoriam, Erhard Gross Publicly Available Download PDF	XLIX
Plenary Lectures
Recent Developments in the Chemistry and Biology of Cyclic Peptides Yuri Ovchinnikov, Gunar Chipens and Vadim Ivanov Requires Authentication Unlicensed Licensed Download PDF	1
Conformational Considerations in the Design of Highly Potent and Long-Acting Peptide Hormone Agonists and Antagonists Victor J. Hruby, James J. Knittel, Henry I. Mosberg, Todd W. Rockway, Brian C. Wilkes and Mac E. Hadley Requires Authentication Unlicensed Licensed Download PDF	19
Semisynthesis of Proteins and Peptides Robin E. Offord Requires Authentication Unlicensed Licensed Download PDF	31
Further Application of the Aqueous-Organic Two-Phase Approach to Enzyme-Catalyzed Peptide-Synthesis Hans-Dieter Jakubke, Peter Kuhl, Andreas Könnecke, Günter Döring, Jörg Walpuski, Andreas Wilsdorf and Nina P. Zapevalova Requires Authentication Unlicensed Licensed Download PDF	43
Interactions of Lipid Bilayers with Corticotropin, Dynorphin, and Enkephalin Peptides Robert Schwyzer, Hans-Ulrich Gremlich and Beat Gysin Requires Authentication Unlicensed Licensed Download PDF	55
Gramicidin A: From Structure Towards the Molecular Mechanism of Action Vadim Ivanov Requires Authentication Unlicensed Licensed Download PDF	73
Structural Comparisons of Retroenantiomeric Cyclic Hexapeptides Dick van der Helm and M.B. Hossain Requires Authentication Unlicensed Licensed Download PDF	91
Circular Dichroism and Conformation of Peptides Related to Oxytocin Ivo Frič, Petr Maloň, Karel Jošt and Karel Bláha Requires Authentication Unlicensed Licensed Download PDF	103
Synthesis of Peptides
Methods of Protection
Adaptation of Side Reactions for Peptide Synthesis Miklos Bodanszky, Maria A. Bednarek, Ai-xue Ji and Agnes Bodanszky Requires Authentication Unlicensed Licensed Download PDF	117
A New Type of Reagents for the Liberation of free Amino Components Jan Izdebski and Stefania Drabarek Requires Authentication Unlicensed Licensed Download PDF	121
The Application of Recently Developed Amino Protecting Groups in Peptide Synthesis Wolfgang Voelter, Jürgen Müller, Charles Beni, Wolfgang Heinzel, Hubert Kaibacher, Ademir Morel and Hartmut Wollmann Requires Authentication Unlicensed Licensed Download PDF	125
Preparation of 4-Sulfobenzyl Esters and their Use in Peptide Synthesis Roland Bindewald, Erika E. Büllesbach, Helmut Zahn, Miklos Bodanszky and Waleed Danho Requires Authentication Unlicensed Licensed Download PDF	129
The 2-Chloroethyl Group for Carboxyl Protection in Peptide Synthesis M. Joaquina S.A. Amaral Trigo and M. Isabel M.R.E. Barbedo Requires Authentication Unlicensed Licensed Download PDF	133
Some Properties of Amino Acid and Peptide Phenacyl Esters Olga Popova, Rudolf Jung and Yuri Mitin Requires Authentication Unlicensed Licensed Download PDF	137
Temporary Substitution of Asparagine by Aspartic Acid in the Synthesis of Peptide Segments of Vasoactive Intestinal Peptide (VIP) W.M.M. Schaaper and D. Voskamp Requires Authentication Unlicensed Licensed Download PDF	141
Methods of Coupling
Recycling of Excess Peptides from Fragment Condensations with Carbonyldiimidazole/1-Hydroxybenzotriazole Activation Christian Birr, Ilona Krück, Rüdiger Pipkorn and Christoph Voss Requires Authentication Unlicensed Licensed Download PDF	145
Fatty Acids as Additives Suppressing Racemization of Amino Acid Residues in Peptide Synthesis by the DCC Method Józef Przybylski, Hanna Kiecznikowska, Gotfryd Kupryszewski, Hans Jeschkeit and Michael Strube Requires Authentication Unlicensed Licensed Download PDF	149
HPLC as a Tool for the Investigation of Peptide Bond Formation Marek Slebioda, Aleksander M. Kolodziejczyk and Teresa Sokoiowska Requires Authentication Unlicensed Licensed Download PDF	153
Application of Phosphinic Acids to Peptide Synthesis R. Ramage, C. Ashton, B. Atrash, D. Hopton and M.J. Parrott Requires Authentication Unlicensed Licensed Download PDF	157
A Reinvestigation of the Mixed Anhydride Method Vinod Kumar Naithani and Anil Kumar Naithani Requires Authentication Unlicensed Licensed Download PDF	163
Do Acylamino Acid and Peptide Anhydrides Exist? N. Leo Benoiton and Francis M.F. Chen Requires Authentication Unlicensed Licensed Download PDF	167
First Results with New Reagents for Peptide Coupling Peter Henklein, Klaus Forner, Hartmut Iliedrich and Peteris Ya. Romanovski Requires Authentication Unlicensed Licensed Download PDF	171
Peptide Syntheses without Isolation of Intermediates Using Biphasic Solvent System Rudolf Dölling and Klaus-Dieter Kaufmann Requires Authentication Unlicensed Licensed Download PDF	175
Some Applications of the Curtius Rearrangement Panayiota Moutevelis-Minakakis and Iphigenia Photaki Requires Authentication Unlicensed Licensed Download PDF	179
Heterodetic Bonds
A New Method for the Selective Synthesis of Unsymmetrical Cystine Peptides Erich Wünsch, Sigrun Romani and Luis Moroder Requires Authentication Unlicensed Licensed Download PDF	183
A Controlled Synthesis of Cyclic Unsymmetrical Cystine Peptides Bearing Two S-S Bridges in the Ring Iphigenia Photaki, Miltiadis Kolovos, Ageliki Stathaki-Ferderigos and Leonidas Zervas Requires Authentication Unlicensed Licensed Download PDF	189
Synthesis of Cysteine and Cystine Containing Peptides through 3-0-[N-Benzyloxycarbony 1-S-Acetamidomethyl- Cysteinyl] -Hydroxy-2-Phenylindenone Stoyan Minchev and Nedyalko Sofroniev Requires Authentication Unlicensed Licensed Download PDF	195
Method of Cyclization of Carba Analogues of Oxytocin Milan Krojidlo, Martin Flegel and Michal Lebl Requires Authentication Unlicensed Licensed Download PDF	199
Synthesis of Isopeptides of Lysine as Fundamental Structural Units of Clavicepamines Gyula Szókàn, Marian Gyenes, Ernő Tyihák and Béla Szende Requires Authentication Unlicensed Licensed Download PDF	203
Synthesis of Leucine Enkephalin- and Aspartame Analogs Containing Thioamide Linkages at Specific Positions K. Clausen, B. Yde and S.-O. Lawesson Requires Authentication Unlicensed Licensed Download PDF	207
Synthesis on Polymeric Supports
Synthetic Studies on the Cecropins R.B. Merrifield, L.D. Vizioli and H.G. Boman Requires Authentication Unlicensed Licensed Download PDF	211
Improved Syntheses of Substance P and Analogues on a Phenolic Resin Support Emanuel Escher, Jean-Marc Lalonde and Stephanos Caranikas Requires Authentication Unlicensed Licensed Download PDF	215
Peptide Ionophores. Synthesis and Characterization of Cyclic Octa- and Decapeptides Containing Leucine and Proline John Halstrøm, Sandor Mozer and Kay Brunfeldt Requires Authentication Unlicensed Licensed Download PDF	219
Histone Model Peptide Synthetized by Solid Phase Fragment Condensation Vladimír Gut, Hana Votavová, Karol Bláha and Jaroslav Šponar Requires Authentication Unlicensed Licensed Download PDF	223
The Biomimetic Gel Phase Synthesis of the RNA-Polymerase II Inhibitor Peptide 6'-Deshydroxy-Amanullin Christian Birr and Bertram Schmitt Requires Authentication Unlicensed Licensed Download PDF	227
Methodological Studies on Gel Phase Synthesis of the Arginine-Rich Propeptide Extension of Proalbumin R. Pipkorn, Chr. Birr, M. Schmid and K. Weigand Requires Authentication Unlicensed Licensed Download PDF	233
Use of the Nbb-Resin and 4-Hydroxymethylphenoxymethyl- Resin in Solid Phase Peptide Synthesis Enrique Pedroso, Anna Grandas, Ramon Eritja and Ernest Giralt Requires Authentication Unlicensed Licensed Download PDF	237
Comparative Syntheses of an Octapeptide Using Continuous Flow (Column) and Conventional Polyamide Solid Phase Methods E. Atherton, Linda E. Cammish and R.C. Sheppard Requires Authentication Unlicensed Licensed Download PDF	241
The Solid Phase Synthesis of Neurotensin and Related Peptides on Polydimethylacrylamide Resins Brian John Williams Requires Authentication Unlicensed Licensed Download PDF	247
Liquid-Phase Synthesis of Biologically Active Peptides on Easily Detachable Poly(Ethylene Glycol) Supports Roberto Colombo Requires Authentication Unlicensed Licensed Download PDF	251
Synthesis of Individual Peptides
Synthesis of Tuftsin under HPLC Control O.A. Kaurov, A.N. Prusakov, A.M. Pivovarov and V.A. Pasechnik Requires Authentication Unlicensed Licensed Download PDF	257
Synthesis of Tuftsin Analogs with Elongated Peptide Chain and a Possible Anticancer Activity Danuta Konopińska, Victor A. Najjar and Miroslaw Luczak Requires Authentication Unlicensed Licensed Download PDF	261
Synthesis of an IgG Fragment Decapeptide and Preliminary Evaluation of its Role on Phagocytosis Stimulation of Human Polymorphonuclear Leukocytes Jean Martinez, Jeanine Laur and François Wintemitz Requires Authentication Unlicensed Licensed Download PDF	265
Synthesis and Pharmacologic Characterization of Glucagon (1-21)-Peptide H. Petersen, B.F. Lundt, N.L. Johansen and F.C. Grønvald Requires Authentication Unlicensed Licensed Download PDF	269
The Synthesis of Peptides Related to Prothrombin Allan Hallett, Alan P. Hope, Michael S. Munns, Reginald Richardson and Geoffrey T. Young Requires Authentication Unlicensed Licensed Download PDF	273
Total Synthesis of Neurotoxin II from the Central Asian Cobra (Naja naja oxiana) venom Vladislav Deigin, Victor Ulyashin, Inessa Mikhaleva and Vadim Ivanov Requires Authentication Unlicensed Licensed Download PDF	277
Synthesis of Labelled Peptides
Catalytic Exchange Labelling of Peptides Derek E. Brundish, M. Grace Combe and R. Wade Requires Authentication Unlicensed Licensed Download PDF	285
Solid Phase Synthesis of Neurotensin Analogues Susceptible to Radiolabelling C. Labbe, D. Blanot, E. Bricas, J.L. Morgat, P. Kitabgi, J.P. Vincent, C. Granier and J. Van Rietschoten Requires Authentication Unlicensed Licensed Download PDF	289
Tritium Incorporation into Histidine by Direct Catalytic Exchange: Labelling of Gonadotropin Releasing Hormone and Analogs Erhard Klauschenz, Michael Bienert, Hartmut Berger, Burkhart Mehlis, Hartmut Niedrich and Ulrich Pleiss Requires Authentication Unlicensed Licensed Download PDF	293
The ³H-Labelling of Peptides by Reduction of Dehydroleucine Paul M. Hardy, Paul W. Sheppard, Derek E. Brundish and Roy Wade Requires Authentication Unlicensed Licensed Download PDF	297
Analogues of [8-ArginineJ Vasopressin for Hormone Receptor Research Falk Fahrenholz, Peter Crause and Jean-Louis Morgat Requires Authentication Unlicensed Licensed Download PDF	301
Synthesis of Peptides Containing Non-Coded Amino Acids
Synthetic Fragments of Bacterial Cell Walls. Physicochemical and Biological Properties Miloš Buděšínsky, Jan Ježek, Viktor Krchňak, Michal Lebl, Milan Zaoral, Jiři Rotta and Radovan Straka Requires Authentication Unlicensed Licensed Download PDF	305
Synthesis of Analogues of Precursors of Bacterial Peptidoglycan Didier Blanot, Androniki Kretsovali, Mohamed Abo-Ghalia, Dominique Mengin-Lecreulx and Jean van Heijenoort Requires Authentication Unlicensed Licensed Download PDF	311
Synthesis of Peptides with α, β-Dehydroaminoacid Residue Barbara Rzeszotarska, Maciej Makowski and Zbigniew Kubica Requires Authentication Unlicensed Licensed Download PDF	315
Synthesis of Dehydro Amino Acids and Peptides Robert H. Mazur and Daniel R. Pilipauskas Requires Authentication Unlicensed Licensed Download PDF	319
α-Hydroxymethylation of Peptides: A Synthetic Route to Peptides Containing α-Hydroxymethy1-Amino Acids Z.J. Kamiński, M.T. Leplawy and Urszula Słomczyńska Requires Authentication Unlicensed Licensed Download PDF	323
L- α-Aminoadipic Acid δ-N-Benzyloxycarbonylamide and its Use in Peptide Synthesis Bogdan Liberek and Regina Kasprzykowska Requires Authentication Unlicensed Licensed Download PDF	327
Synthesis of ß-Homo-L-Proline Analogues of Peptide Hormones Krzysztof Bańkowski and Aleksandra Misicka Requires Authentication Unlicensed Licensed Download PDF	331
Optically Active Neopentylglycine and its Applications in Peptide Chemistry Jan Pospíšek and Karel Bláha Requires Authentication Unlicensed Licensed Download PDF	333
Monodisperse Conjugates of Catecholamines Kenneth A. Jacobson, Roberto P. Rosenkranz, Michael S. Verlander, Kenneth L. Melmon and Murray Goodman Requires Authentication Unlicensed Licensed Download PDF	337
Total Synthesis of Althiomycin Tetsuo Shiba and Kaoru Inami Requires Authentication Unlicensed Licensed Download PDF	341
Peptide Tricyclic Thia-Cyclols from Linear Precursors Giancarlo Zanotti, Francesco Pinnen, Gino Lucente, Silvio Cerrini, Walter Fedeli and Fernando Mazza Requires Authentication Unlicensed Licensed Download PDF	345
Semi-Synthesis
Synthesis of Cytochrome C-(66-104) Nonatriacontapeptide and Analogues P.B.W. Ten Kortenaar, G.I. Tesser and R.J.F. Nivard Requires Authentication Unlicensed Licensed Download PDF	349
Cytochrome c̱ Semisynthesis Using Enzymic Resynthesis Techniques Amanda E. I. Proudfoot and Carmichael J. A. Wallace Requires Authentication Unlicensed Licensed Download PDF	353
Semisynthetic Analogs of Globomycin John D. Glass, Brian Hayes and Masayori Inouye Requires Authentication Unlicensed Licensed Download PDF	357
Semisynthetic Studies on the Bovine Trypsin-Kallikrein Inhibitor Laura Biondi, Bruno Filippi, Fernando Filira, Virgilio Giormani and Raniero Rocchi Requires Authentication Unlicensed Licensed Download PDF	361
Synthesis of a Hybrid Chicken/Human Insulin H.-J. Wieneke, G. Wolf, W. Wolff, E. E. Büllesbach, H.-G. Gattner and D. Brandenburg Requires Authentication Unlicensed Licensed Download PDF	367
Semisyntheses of Insulin Analogues by Replacement of the Sequence Al-4 Derek Saunders, Klaus Freude, Vinod Kumar Naithani, Dietrich Brandenburg and Stoytcho Stoev Requires Authentication Unlicensed Licensed Download PDF	371
Synthesis of Peptides Using Enzymes
Enzymatic Peptide Synthesis Fred Widmer, Motonori Ohno, Mark Smith, Nancy Nelson and Christian B. Anfinsen Requires Authentication Unlicensed Licensed Download PDF	375
Amidation of Synthetic Peptides by Pituitary Enzyme: Specificity and Mechanism of the Reaction A.F. Bradbury and D.G. Smyth Requires Authentication Unlicensed Licensed Download PDF	381
Reaction Mechanism in Trypsin Catalyzed Synthesis of Human Insulin Studied by ¹⁷O-NMR Spectroscopy J. Markussen and K. Schaumburg Requires Authentication Unlicensed Licensed Download PDF	387
Trypsin-Catalyzed Oligomerization of the Ala-Ala-Arg Tripeptide Václav Čeřovský and Karel Jošt Requires Authentication Unlicensed Licensed Download PDF	395
Thermitase-Catalyzed Hydrolysis of the C-Terminal Ester Group of Protected Peptide Ester Derivatives Peter Hermann and Lothar Salewski Requires Authentication Unlicensed Licensed Download PDF	399
Reversibility of Tryptic Hydrolysis in a Model Nonapeptide Sequence Vishwas S. Ganu and John D. Glass Requires Authentication Unlicensed Licensed Download PDF	403
Synthesis and Characterization of α- and/or ε-Substituted Lysine Peptides Peter Stehle, Bernhard Kühne, Annelore Plessing, Peter Fürst and Peter Pfaender Requires Authentication Unlicensed Licensed Download PDF	407
Purification, Characterization and Analytics
Isolation by Preparative HPLC and Characterization of Major Components after Cyclization of a Decapeptide Per Larsen, Ole Schou and Thorkild Christensen Requires Authentication Unlicensed Licensed Download PDF	411
Separation of Basic, Hydrophilic Peptides by Reversed- Phase Ion-Pair Chromatography. III. A Progress Report Bengt Fransson and Ulf Ragnarsson Requires Authentication Unlicensed Licensed Download PDF	415
Pre-Column Derivatization in HPLC of Peptides Gyula Szókán and György Pintér Requires Authentication Unlicensed Licensed Download PDF	419
Fast Atom Bombardment Mass Spectrometry - a New Tool for Peptide Sequence Analysis Wilfried A. König, Mitat Aydin, Uwe Schulze and Marian Rinken Requires Authentication Unlicensed Licensed Download PDF	423
Progress Towards a Post-Synthetic Chiral Analysis of Peptides John S. Davies, A. Karim Mohammed and Essam Hakeem Requires Authentication Unlicensed Licensed Download PDF	431
Direct Peptide Sequencing after TLC on Silica Gel without Substance Elution Regine Kraft, Albrecht Otto and Gerhard Etzold Requires Authentication Unlicensed Licensed Download PDF	437
Structure-Activity Relations
Neurohypophyseal Hormones
Two Analogues of Oxytocin with Modified Proline Cyclic Structure Zdenko Procházka, Michal Lebl, Tomislav Barth, Jan Hlaváček and Karel Jošt Requires Authentication Unlicensed Licensed Download PDF	441
Synthesis of new Active and Highly Selective Analogues of Oxytocin and Arginine-Vasopressin Zbigniew Grzonka, Franciazek Kasprzykowski, Bernard Lammek, Diana Gazis and Irving L. Schwartz Requires Authentication Unlicensed Licensed Download PDF	445
CNS - Active Vasopressin Analogues František Brtnik, Tomislav Barth, Jana Škopková and Karel Jošt Requires Authentication Unlicensed Licensed Download PDF	449
Investigation of Position 2 and 3 of Vasopressins Ivo Bláha, Viktor Krchńak, Milan Zaoral and Danuta Konopinska Requires Authentication Unlicensed Licensed Download PDF	453
Analogues of Neurohypophysial Hormones Containing a D-Amino Acid in Position 2 Michal Lebl, Tomislav Barth, Linda Servítová, Jiřina Slaninová and Karel Jošt Requires Authentication Unlicensed Licensed Download PDF	457
Penicillamine-Containing Analogues of Neurohypophysial Hormones Petr Šimek, Tomislav Barth, F. Brtnik, J. Slaninová and K. Jošt Requires Authentication Unlicensed Licensed Download PDF	461
9-Substituted Vasopressin Analogs with Substantial Antidiuretic Activity D. Gazis, A. Buku and I.L. Schwartz Requires Authentication Unlicensed Licensed Download PDF	465
Interactions of Deamino-6-Carba-0xytocin Analogues in Rat Kidney and Liver Membrane Systems T. Barth, M. Lebl, K. Jošt, B. Cantau, D. Butlan, G. Guillon and S. Jard Requires Authentication Unlicensed Licensed Download PDF	467
Opioid Peptides
Synthesis and Biological Activity of New Enkephalin Analogues R. Paruszewski, R. Matusiak, E. Gmitrzuk, W. Gumułka and P. Janicki Requires Authentication Unlicensed Licensed Download PDF	471
Biochemical and Pharmacological Investigations of Peripheral and Brain δ-Opiate Receptors Using Tyr-D-Thr-Gly- Phe-Leu-Thr, a New Fully Specific 6-Ligand B.P. Roques, G. Gacel, P. Dodey, J.-M. Zajac and M.C. Fournié-Zaluski Requires Authentication Unlicensed Licensed Download PDF	475
Double Opiate Peptides. A Hypothesis of Two Different Mechanisms of Opiate Actions A.W. Lipkowski, M. Konopka, B. Osipiak and W.S. Gumuika Requires Authentication Unlicensed Licensed Download PDF	481
Synthesis and Activity of Kyotorphin and its Analogs L. Baláspiri, K. Kovács, A. Geese, G. Telegdy and K. Neubert Requires Authentication Unlicensed Licensed Download PDF	487
Opioid Activity of Synthetic "Small Demorphins" R. Tomatis, S. Salvadori and G. Sarto Requires Authentication Unlicensed Licensed Download PDF	495
Structure-Activity Relationship of Dermorphin K. Darłak, Z. Grzonka, P. Janicki, A. Członkowski and S.W. Gumułka Requires Authentication Unlicensed Licensed Download PDF	501
Structural Modifications of β-Casomorphin-5: Synthesis and Pharmacology B. Hartrodt, K. Neubert, H. Matthies, H.-L. Rüthrich, H. Stark and A. Barth Requires Authentication Unlicensed Licensed Download PDF	505
Substance P
Substance P: The "Yin-Yang" of Behavior? J.M. Stewart and M.E. Hall Requires Authentication Unlicensed Licensed Download PDF	511
Hydrophilic Analogs of Substance P: Introduction of Sugar Acids and Sulfonium Groups M. Bienert, K. Forner, B. Mehlis, H. Niedrich, J. Bergmann and R. Kraft Requires Authentication Unlicensed Licensed Download PDF	517
Influence of the Methionine Sidechain on the Biological Activity of Substance P D. Theodoropoulos, C. Poulos, D. Gatos, P. Cordopatis, R. Couture, J. Mizrahi, D. Regoli and E. Escher Requires Authentication Unlicensed Licensed Download PDF	521
Substance P Analogues Containing Para-Substituted Phenylalanine: Synthesis and Pharmacological Properties E. Munekata and I. Kanazawa Requires Authentication Unlicensed Licensed Download PDF	527
Synthesis of Potent and Specific Antagonists of Substance P E. Escher, J. Mizrahi, S. Caranikas, P. D’Orléans-Juste and D. Regoli Requires Authentication Unlicensed Licensed Download PDF	531
Substance P: Inactivation in CNS, Enzymatically Resistant Analogue and Development of "Brain Selective" Agonist B.E.B. Sandberg, M.R. Hanley, L.L. Iversen, J.E. Maggio, R.R.D. Pinnock and S.P. Watson Requires Authentication Unlicensed Licensed Download PDF	535
Other Biologically Active Peptides
Some Pharmaceutical Aspects of Peptide Research L. Kisfaludy Requires Authentication Unlicensed Licensed Download PDF	543
The Synthesis and Gonadotropic Activity of [D-Tle⁶, Pro-NH-Et⁹]LRF M. Flegel, J. Pospišek, J. Picha and D. Pichová Requires Authentication Unlicensed Licensed Download PDF	551
The Role of N-Acyl Groups in the Inhibitory Activity of LH-RH Analogues I. Mezö, J. Seprödi, J. Erchegyi, I. Teplán and B. Flerko Requires Authentication Unlicensed Licensed Download PDF	555
Gonadotropin Releasing Hormone and its Analogs Desensitize Pituitary GnRH Action G. Kéri, K. Nikolics and I. Teplán Requires Authentication Unlicensed Licensed Download PDF	559
DSIP: Novel Developments in Structure-Functional Studies I. Mikhaleva, A. Sargsyan and V. Ivanov Requires Authentication Unlicensed Licensed Download PDF	563
The Active Centres of Gastrin and Cholecystokynin: Syntheses, Conformational Problems, Correlation between Chemical Structure and Biological Activity B. Penke, M. Zarandi, G.K. Toth, K. Kovács, M. Fekete, G. Telegdy and P. Pham Requires Authentication Unlicensed Licensed Download PDF	569
What is the Minimum Active Centre of Gastrin? M. Zarándi, B. Penke, J. Varga, K. Kovács, G. Holczinger and T. Kádár Requires Authentication Unlicensed Licensed Download PDF	577
Structure-Activity Relationships of Highly Potent and Specific Gctapeptide Analogues of Somatostatin W. Bauer, U. Briner, W. Doepfner, R. Haller, R. Huguenin, P. Marbach, T.J. Petcher and J. Pless Requires Authentication Unlicensed Licensed Download PDF	583
Photoreactive [Leu⁹]-a-MSH Derivatives for Receptor Labelling A.N. Eberle, J. Girard, P.N.E. de Graan and F. F.C.G. van de Veerdonk Requires Authentication Unlicensed Licensed Download PDF	589
Degradation of α-Melanotropin by the Enzymes of the Soluble Fraction of Rat Brain Homogenate H. Medzihradszky-Schweiger, J. Szécsi and K. Medzihradszky Requires Authentication Unlicensed Licensed Download PDF	593
Solid Phase Synthesis of Amunine (CRF), Sauvagine and Two Urotensin I J. Rivier, J. Spiess, C. Rivier, R. Galyean, W. Vale and K. Lederis Requires Authentication Unlicensed Licensed Download PDF	597
Proctolin: Synthesis, Enzymatic Degradation and Effect on the Cyclic Nucleotide System H. Arold, C. Liebmann, S. Reissmann and J. Scheidt Requires Authentication Unlicensed Licensed Download PDF	603
Phosphonopeptides, Novel Inhibitors of Bacterial Cell Wall Biosynthesis C.H. Hassall, F.R. Atherton, M.J. Hall, R.W. Lambert, W.J. Lloyd and P.S. Ringrose Requires Authentication Unlicensed Licensed Download PDF	607
Urinary Excretion of Biologically Active Peptides and/or Peptide-Like Material in Various Disorders J.H. Johansen, J.B. Bøler, K.L. Reichelt, P.D. Edminson and N.K. Pape Requires Authentication Unlicensed Licensed Download PDF	613
Inhibitors and Binding Studies
Synthesis and Properties of Peptide Ketones S. Fittkau and G. Jahreis Requires Authentication Unlicensed Licensed Download PDF	617
Enkephalin Diazomethyl and Chloromethyl Ketones: Synthesis and Biological Activity K. Medzihradszky, J. Szécsi, G. Csanády and J. Hepp Requires Authentication Unlicensed Licensed Download PDF	623
Use of Quantitative Lipophilicity Relationships for the Design of Renin Inhibitors J. Burton Requires Authentication Unlicensed Licensed Download PDF	629
Specific Inhibitors of Renin M. Szelke, A. Hallett, D.M. Jones, J. Sueiras, B. Atrash, B. Leckie, M. Tree and A.F. Lever Requires Authentication Unlicensed Licensed Download PDF	635
Anionic Inhibitors of Elastase E. Kasafírek, P. Frič and J. Slabý Requires Authentication Unlicensed Licensed Download PDF	639
Inhibition of Thrombin with H- and Boc-D-Phe-Pro-Agm S. Bajusz, E. Barabás and D. Bagdy Requires Authentication Unlicensed Licensed Download PDF	643
Analogues of Chymostatin I.J. Galpin, A. H. Wilby and R.J. Beynon Requires Authentication Unlicensed Licensed Download PDF	649
Binding Studies of Glucagon Antagonists V.J. Hruby, J.T. Pelton, R. McKee and D. Trivedi Requires Authentication Unlicensed Licensed Download PDF	653
Determination of the Toxic and Antigenic Sites of Peptide Snake Venom Short Neurotoxins A. Ménez, J.-C. Boulain and P. Fromageot Requires Authentication Unlicensed Licensed Download PDF	657
Design and Synthesis of Two Peptides as Models for the Antigenic Sites of the Toxin II of the Scorpion Androctonus australis Hector C. Granier, E. Bahraoui, J. Van Rietschoten, H. Rochat and M. El Ayeb Requires Authentication Unlicensed Licensed Download PDF	663
Immunology Related Peptides
Chemical Approaches to Improve Immunoassays of Peptide Hormones L. Moroder, M. Gemeiner, H. Kaibacher, R. Nyfeler and E. Wünsch Requires Authentication Unlicensed Licensed Download PDF	667
Antineoplastic and Immunogenic Effects of Tuftsin (Thr-Lys-Pro-Arg) and its Analogs V.A. Najjar, D. Konopinska, M.K. Chaudhuri and L. Linehan Requires Authentication Unlicensed Licensed Download PDF	673
Synthesis and Biological Assays of Peptides from a Tuberculin-Active Protein J. Šavrda Requires Authentication Unlicensed Licensed Download PDF	679
Synthesis and Immunoreactivity of Escherichia Coli Heat Stable Enterotoxins Analogs A. Duflot, H. Gras-Masse, A. Tartar, E. Duflot and P. Boquet Requires Authentication Unlicensed Licensed Download PDF	683
Preparation and Antigenicity of the C-Terminal Fragments of Human Leukocyte Interferons α2 and α1 M. Ohno, F. Widmer, M.E. Smith, H. Arnheiter and K.C. Zoon Requires Authentication Unlicensed Licensed Download PDF	687
Immunological Properties of Hapten-Peptide Conjugates: The Effect of Size, Lipophilic Substituents and Haptenic Distance on Tolerogenicity and Anaphylactogenicity I. F. Luescher and C.H. Schneider Requires Authentication Unlicensed Licensed Download PDF	693
Conformational Studies
Conformation: Model Peptides
Conformational Features of Alternating L, D Peptides A. Bavoso, E. Benedetti, B. Di Biasio, V. Pavone, C. Pedone, V. Barone, G. Esposito, F. Lelj and G.P. Lorenzi Requires Authentication Unlicensed Licensed Download PDF	699
Conformation of Cyclic Hexapeptides Studied by the Modified Factor Analysis of Circular Dichroism Spectra P. Pančoška, K. Bláha and J. Vičar Requires Authentication Unlicensed Licensed Download PDF	705
Conformational Energy Calculations of Heterodetic Cyclic Hexapeptides Related to Oxytocin Ring Moiety P. Maloň, G.V. Nikiforovich and K. Bláha Requires Authentication Unlicensed Licensed Download PDF	709
Conformational Energy Analysis of Oxytocin Molecule V. Krchňák Requires Authentication Unlicensed Licensed Download PDF	713
Conformational Analysis of Peptides Substrate of N-Glycosylation E. Giralt, M. Pons, J.M. Ricart, J.J. Perez, C. Granier and J. Van Rietschoten Requires Authentication Unlicensed Licensed Download PDF	717
Serine and ß-Folding M. Marraud and A. Aubry Requires Authentication Unlicensed Licensed Download PDF	721
X-Ray Structure and Conformation in Solution of Peptides Containing α-Aminoisobutyric Acid Residues G. Jung, R. Bosch, H. Brückner, E. Katz, H. Schaal, H. Schmitt, J. Strähle, K.-P. Voges and W. Winter Requires Authentication Unlicensed Licensed Download PDF	725
Preferred Conformations of Host-Guest Peptides M. Mutter, F. Maser, B. Klein, C. Toniolo and G.M. Bonora Requires Authentication Unlicensed Licensed Download PDF	729
Conformation: Biologically Active Peptides
Conformation Calculations and Biologically Active Conformations of Cyclopeptides G. Nikiforovich, S. Rozenblit, I. Liepina and G. Chipens Requires Authentication Unlicensed Licensed Download PDF	735
Peptaibol Antibiotics: A Study on the Helical Structure of Emerimicins C. Toniolo, G.M. Bonora, E. Benedetti, A. Bavoso, B. di Biasio, V. Pavone and C. Pedone Requires Authentication Unlicensed Licensed Download PDF	741
Conformational and Ionophoric Properties of Prolyl Containing Analogs of Valinomycin T. Balashova, L. Fonina, G. Avotina and V. Xvanov Requires Authentication Unlicensed Licensed Download PDF	745
Synthesis of the Postulated Calcium Binding Site I of Calmodulin and Binding Studies F. Marchiori, G. Borin, G. Chessa and E. Peggion Requires Authentication Unlicensed Licensed Download PDF	751
X-Ray Structural Study of Ionophores of a Valinomycin Group V. Popovich and V. Pletnev Requires Authentication Unlicensed Licensed Download PDF	755
Conformational Studies on Gaba-Enkephalinamides C. Di Bello, S. Andini, L. Ferrara, R. Napolitano and L. Paolillo Requires Authentication Unlicensed Licensed Download PDF	759
Conformational Studies of the "in vitro" Potent Opiate [D-Met², Trp⁴, Pro⁵] Enkephalinamide by Fluorescence and Theoretical Calculations J.-M. Garcia Anton, F. Reig, G. Valencia, J.J. Garcia Dominquez, R. Guillard, J.-P. Demonte and A. Englert Requires Authentication Unlicensed Licensed Download PDF	763
Configuration of the Azo Bridge in Azo-Enkephalin I.Z. Siemion, A. Jankowski, M. Lisowski and Z. Szewczuk Requires Authentication Unlicensed Licensed Download PDF	767
Self-Association of Substance P and its C-Terminal Sequences K. Gast, J. Behlke, M. Rüger, M. Bienert and B. Mehlis Requires Authentication Unlicensed Licensed Download PDF	771
Spatial Structure of Bradykinin Potentiating Peptide BPP_9α S. Reißmann, H. Arold, M.P. Filatova, N.A. Krit and I. Frič Requires Authentication Unlicensed Licensed Download PDF	775
Guest-Host Relationship in Bradykinin Peptides V. Dive, K. Lintner, S. Fermandjian, S.S. Pierre and D. Regoli Requires Authentication Unlicensed Licensed Download PDF	781
Importance of Residue 5 in Antiotensin II C. Sakarellos, F. Piriou, M. Juy, F. Torna, H. Lam-Thanh, K. Lintner, S. Fermandjian, M.C. Khosla, R.R. Smeby and F.M. Bumpus Requires Authentication Unlicensed Licensed Download PDF	785
Circular Dichroism Aids Interpretation of Structure- Activity Relationship of Somatostatin Analogs D.F. Veber, W.C. Randall, R.F. Nutt, R.M. Freidinger, S.F. Brady, D.S. Perlow, P. Curley, W.J. Paleveda, R.G. Strachan, F.W. Holly and R. Saperstein Requires Authentication Unlicensed Licensed Download PDF	789
The Conformational Equilibrium of the Peptide Hormone Somatostatin and some Analogues in Aqueous Solution K. Hallenga, F. Vlaeminck, G. Van Binst, M. Knappenberg, A. Michel and J. Zanen Requires Authentication Unlicensed Licensed Download PDF	793
Application of Homonuclear and Heteronuclear Two-Dimensional NMR Spectroscopy to Cyclolinopeptide A (1) H. Kessler and R. Schuck Requires Authentication Unlicensed Licensed Download PDF	797
Role of the N-Terminal Fragment on the Stability of the Porcine Pancreatic Secretory Tryps in Inhibitors (KAZAL) A. Scatturin, V. Periotto, M. Guarneri, E. Menegatti and A. De Marco Requires Authentication Unlicensed Licensed Download PDF	801
Relationship between the Steric Structure of Insulin Derivatives and their Biological Activity G. Vlasov, N. Izvarina and N. Illarionova Requires Authentication Unlicensed Licensed Download PDF	805
Studies of Hydrogen Bonding in Relation to Oxytocin Activity D. Gazis, J. Roy, U. Roy, J.D. Glass and I.L. Schwartz Requires Authentication Unlicensed Licensed Download PDF	809
Synthesis, Conformation and Interaction with a Decanucleotide of the Fragment (26-39) of the "Cro" Protein from Bacteriophage λ R. Mayer, G. Lancelot and C. Hélène Requires Authentication Unlicensed Licensed Download PDF	815
Abbreviations Requires Authentication Unlicensed Licensed Download PDF	819
Subject Index Requires Authentication Unlicensed Licensed Download PDF	829
Authors' Index Requires Authentication Unlicensed Licensed Download PDF	841
Backmatter Requires Authentication Unlicensed Licensed Download PDF	847

Language: German
Publisher: De Gruyter
Edition: Reprint 2019
Pages
- Front matter: 55
- Main content: 846
Illustrations
- Other: Num. figs.

eBook

Published: May 20, 2019
ISBN: 9783111694344

Hardcover

Published: April 1, 1983
ISBN: 9783110095746