Flavins and Flavoproteins 1993: Proceedings of the Eleventh International Symposium, Nagoya, Japan, July 27–31, 1993

Published by De Gruyter 1994

Flavins and Flavoproteins 1993

Proceedings of the Eleventh International Symposium, Nagoya, Japan, July 27–31, 1993

Edited by: Kunio Yagi

https://doi.org/10.1515/9783110885774

Contents

Frontmatter Publicly Available Download PDF	I
PREFACE Publicly Available Download PDF	V
Committees Publicly Available Download PDF	VII
CONTENTS Publicly Available Download PDF	IX
THEORETICAL AND CHEMICAL APPROACH
Use of Molecular Orbital Calculations in Studies on Mechanisms of Enzyme Catalysis I.M.C.M. Rietjens, M.G. Boersma, A.E.M.F. Soffers, N.H.P. Cnubben, J. Koerts, S. Peelen, W.J.H. van Berkel, C. Veeger and J. Vervoort Requires Authentication Unlicensed Licensed Download PDF	3
A theoretical approach of the mechanism of C(4a)-peroxyflavin catalyzed reactions C. Veeger, I.M.C.M. Rietjens and J. Vervoort Requires Authentication Unlicensed Licensed Download PDF	13
Semiempirical calculations on properties of (iso)alloxazines in ground and excited states Henryk Szymusiak Requires Authentication Unlicensed Licensed Download PDF	23
Pathways for a 4^a-hydroxy-4^a,5-dihydroflavin radical in the hydroxylation of aromatics Humphrey I. X. Mager and Shiao-Chun Tu Requires Authentication Unlicensed Licensed Download PDF	27
CHEMICAL SYNTHESIS OF NEKOFLAVIN K. Matsui and S. Kasai Requires Authentication Unlicensed Licensed Download PDF	31
NOVEL 5 - SUBSTITUTED 5 - DEAZAFLAVINS : SYNTHESIS AND APPLICATIONS AS ACTIVE SITE PROBES FOR FLAVOPROTEINS Yerramilli V.S.N. Murthy and Vincent Massey Requires Authentication Unlicensed Licensed Download PDF	35
D-Lactate Dehydrogenase Model. Oxidation of a-Hydroxy Acid by Functionalized Oxidation Active flavin Mimic in the Presence of Zn²⁺ and Base in t-Butanol Y. Yano, K. Mitsui, Y. Ohsawa and T. Nabeshima Requires Authentication Unlicensed Licensed Download PDF	39
Mechanism of Flavin Reduction By Cu(I)-EDTA Complex Benfang Lei and Shiao-Chun Tu Requires Authentication Unlicensed Licensed Download PDF	43
SELF-ASSOCIATION OF FLAVIN: INTERACTION OF FMN WITH ALBUMIN Tetsuo Ishida and Kihachiro Horiike Requires Authentication Unlicensed Licensed Download PDF	47
BIOSYNTHESIS OF FLAVINS
STUDIES ON THE BIOSYNTHESIS OF FLAVINS. STRUCTURE AND MECHANISM OF 6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE A. Bacher, K. Ritsert, K. Kis, K. Schmidt-Base, R. Huber, R. Ladenstein, J. Scheuring, S. Weinkauf and M. Cushman Requires Authentication Unlicensed Licensed Download PDF	53
BIOSYNTHESIS OF RIBOFLAVIN. CLONING, SEQUENCING, MAPPING, AND HYPEREXPRESSION OF THE GENES ribA CODING FOR GTP CYCLOHYDROLASE II AND ribC CODING FOR RIBOFLAVIN SYNTHASE OF ESCHERICHIA COLL S. Eberhardt, G. Richter, H. Ritz, J. Brandt and A. Bacher Requires Authentication Unlicensed Licensed Download PDF	63
BIOSYNTHESIS OF RIBOFLAVIN: ENZYMATIC FORMATION OF 6,7-DIMETHYL-8-RIBITYLLUMAZINE IN Saccharomyces cerevisiae J.J. García-Ramírez, M.A. Santos and J.L. Revuelta Requires Authentication Unlicensed Licensed Download PDF	67
ELECTRON MICROSCOPIC STUDIES ON THE LUMAZINE SYNTHASE/ RIBOFLAVIN SYNTHASE COMPLEX OF BACILLUS SUBTILIS S. Weinkauf, J. Brandt and A. Bacher Requires Authentication Unlicensed Licensed Download PDF	71
¹⁹F NMR STUDIES ON LUMAZINE PROTEIN FROM PHOTOBACTERIUM PHOSPHOREUM J. Scheuring, J. Lee, M. Cushman, H. Oschkinat and A. Bacher Requires Authentication Unlicensed Licensed Download PDF	75
19^F NMR STUDIES ON THE MECHANISM OF RIBOFLAVIN SYNTHASE J. Scheuring, M. Cushman, H. Oschkinat and A. Bacher Requires Authentication Unlicensed Licensed Download PDF	79
OXIDASES
STUDIES ON ACTIVE SITE MUTANTS OF SPINACH GLYCOLATE OXIDASE Peter Macheroux and Ylva Lindqvist Requires Authentication Unlicensed Licensed Download PDF	85
HIGH-LEVEL EXPRESSION OF RAT KIDNEY HYDROXY ACID OXIDASE IN ESCHERICHIA COLI: PURIFICATION AND CHARACTERIZATION OF THE RECOMBINANT PROTEIN Ahmed Belmouden and Florence Lederer Requires Authentication Unlicensed Licensed Download PDF	95
The Influence of Substrate Structure on the Redox Reactions of Monoamine Oxidases Rona R. Ramsay, Sergey O. Sablin and Thomas P. Singer Requires Authentication Unlicensed Licensed Download PDF	99
QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIPS IN THE OXIDATION OF BENZYLAMINE ANALOGUES BY BOVINE LIVER MONOAMINE OXIDASE B Mark C. Walker and Dale E. Edmondson Requires Authentication Unlicensed Licensed Download PDF	109
Experimental Probes of Hydrogen Tunneling in Bovine Liver Monoamine Oxidase B Thoriakur Jonsson, Judith P. Klinman and Dale E. Edmondson Requires Authentication Unlicensed Licensed Download PDF	117
Stereospecificity and Deuterium Isotope Effect in the Oxidative Deamination Catalyzed by Flavine and Non-flavine Amine Oxidases P. H. Yu and B.A. Davis Requires Authentication Unlicensed Licensed Download PDF	123
CHARACTERIZATION OF L-ASPARTATE OXIDASE OVEREXPRESSED IN E. COLI A. Negri, M. Mortarino, T. Simonie, G. Tedeschi, S. Ronchi and H.G. Gassen Requires Authentication Unlicensed Licensed Download PDF	127
IDENTIFICATION OF ANOTHER SUBUNIT IN L-PHENYLALANINE OXIDASE FROM PSEUDOMONAS SP. P-501 AND THE PRIMARY STRUCTURE OF THE SUBUNIT Etsuko B. Mukouyama, Haruo Suzuki, Toshihide Sasaki and Hirokazu Koyama Requires Authentication Unlicensed Licensed Download PDF	137
Kinetic Isotope Effects on Reductive Half-Reactions of Flavoprotein Oxidases P.F. Fitzpatrick, J.M. Denu, J.J. Emanuele and V. Menon Requires Authentication Unlicensed Licensed Download PDF	141
Effects of Ligands on the Reactivities of Reduced and Semiquinoid Forms of D-Amino Acid Oxidase Y. Nishina, K. Sato and K. Shiga Requires Authentication Unlicensed Licensed Download PDF	151
Thermodynamic Study of FAD Binding in D-Amino Acid Oxidase F. Tanaka Requires Authentication Unlicensed Licensed Download PDF	155
Structure of Human D- Amino Acid Oxidase Gene Kiyoshi Fukui Requires Authentication Unlicensed Licensed Download PDF	159
AMINO ACID SEQUENCE OF D-AMINO ACID OXIDASE FROM THE YEAST Rhodotorula gracilis L. Faotto, L. Pollegioni, F. Ceciliani, G. Gadda, S. Ronchi and M.S. Pilone Requires Authentication Unlicensed Licensed Download PDF	163
CHEMICAL MODIFICATION OF ARGEVINE GROUPS IN D-AMINO ACID OXIDASE FROM Rhodotorula gracilis Involvement in catalysis and assignment in the sequence G. Gadda, A. Negri and M.S. Pilone Requires Authentication Unlicensed Licensed Download PDF	167
FUNCTIONAL AND STRUCTURAL ASPECTS OF D-AMINO ACID OXIDASE FROM Rhodotorula gracilis PROBED BY LIMITED PROTEOLYSIS Loredano Pollegioni, Fabrizio Ceciliani, Bruno Curti, Severino Ronchi and Mirella S. Pilone Requires Authentication Unlicensed Licensed Download PDF	171
THE CRYSTAL STRUCTURE OF CHOLESTEROL OXIDASE. MECHANISTIC IMPLICATIONS FOR FAD DEPENDENT ALCOHOL OXIDATION Alice Vrielink, Jiayao Li, Peter Brick and David Blow Requires Authentication Unlicensed Licensed Download PDF	175
Nitroalkane-Oxidizing Flavoenzymes Kenji Soda, Tatsuo Kurihara, Marek Tchorzewski, Nobuyoshi Esaki and Nobuko Ohishi Requires Authentication Unlicensed Licensed Download PDF	185
A 340-nm Chromophore of Nitroalkane Oxidase from Fusarium oxysporum Tatsuo Kurihara, Nobuyoshi Esaki, Kenji Soda and Nobuko Ohishi Requires Authentication Unlicensed Licensed Download PDF	195
OXYGENASES
LACTATE MONOOXYGENASE: STUDIES OF ACTIVE SITE MUTATIONS U. Müh, C. H. Williams and V. Massey Requires Authentication Unlicensed Licensed Download PDF	201
The Mobile Flavin of Parahydroxybenzoate Hydroxylase - A Case for Major Structural Dynamics in Catalysis Barrie Entsch, Bruce A. Palfey, Michael S. Lumberg, David P. Ballou and Vincent Massey Requires Authentication Unlicensed Licensed Download PDF	211
Structures of Mutant p-Hydroxybenzoate Hydroxylases: Evidence for an Alternative Mode of Flavin Binding Myoung S. Lah, Domenico Gatti, Herman A. Schreuder, Bruce A. Palfey and Martha L. Ludwig Requires Authentication Unlicensed Licensed Download PDF	221
Substrate and Effector Specificity of Two Active-Site Mutants of p-Hydroxybenzoate Hydroxylase from Pseudomonas fluorescens W.J.H. van Berkel, F.J.T. van der Bolt, M.H.M. Eppink, A. de Kok, I.M.C.M. Rietjens, C. Veeger and J. Vervoort Requires Authentication Unlicensed Licensed Download PDF	231
Solvent Isotope Effects on p-Hydroxybenzoate Hydroxylase Bruce A. Palfey, David P. Ballou and Vincent Massey Requires Authentication Unlicensed Licensed Download PDF	235
IMMUNOLOGICAL STUDIES ON THE STRUCTURE OF 4-AMINOBENZOATE HYDROXYLASE FROM AGARICUS BISPORUS Hideaki Tsuji, Tatsuzo Oka, Masumi Kimoto, Yasuo Natori, Tadashi Ogawa and Yeong-Man Hong Requires Authentication Unlicensed Licensed Download PDF	239
STUDIES ON p-HYDROXYPHENYLACETATE-3-HYDROXYLASE Usha Arunachalam and Vincent Massey Requires Authentication Unlicensed Licensed Download PDF	243
Fluorescent Intermediates and the Reaction Mechanism of Phenol Hydroxylase Kazuko Maeda-Yorita and Vincent Massey Requires Authentication Unlicensed Licensed Download PDF	247
Application of pulse radiolysis to produce absorbing species of substrates for flavoprotein hydroxylases R.F. Anderson Requires Authentication Unlicensed Licensed Download PDF	251
Mammalian Flavin-Containing Monooxygenase Catalyzed Conversion of 4-Halo-NMethylanilines J. Vervoort, M.G. Boersma, N.H.P. Cnubben, W.J.H. van Berkel, J. Koerts, J.A. Boeren and I.M.C.M. Rietjens Requires Authentication Unlicensed Licensed Download PDF	255
2-AMINOBENZOYL-CoA-MONOOXYGENASE/REDUCTASE, AN ENZYME WITH TWO DISTINCT FUNCTIONS AND ONE ACTIVE CENTER B. Langkau and S. Ghisla Requires Authentication Unlicensed Licensed Download PDF	259
Characteristic Properties and Kinetic Analysis of Neurotoxins for Porcine FAD-containing Monooxygenase Ru-Feng Wu and Yoshiyuki Ichikawa Requires Authentication Unlicensed Licensed Download PDF	263
Genomic DNA Structure of a Unique Flavoprotein, 2-Nitropropane Dioxygenase from Hansenula rnrakii Marek Tchorzewski, Tatsuo Kurihara, Nobuyoshi Esaki and Kenji Soda Requires Authentication Unlicensed Licensed Download PDF	267
DEHYDROGENASES AND ELECTRON TRANSFER
THREE DIMENSIONAL STRUCTURES OF ACYL-CoA DEHYDROGENASES: STRUCTURAL BASIS OF SUBSTRATE SPECIFICITY J.J.P. Kim, M. Wang, S. Djordjevic, R. Paschke, D.W. Bennett and J. Vockley Requires Authentication Unlicensed Licensed Download PDF	273
MECHANISM OF a,ß-DEHYDROGENATION BY ACYL-COA DEHYDROGENASES S. Ghisla, S. Engst, P. Vock, V. Kieweg, P. Brosst, A. Nandy, I. Rasched and A.W. StraussH Requires Authentication Unlicensed Licensed Download PDF	283
13C- and 15N-NMR Studies of Medium-Chain Acyl-CoA Dehydrogenase from Porcine Kidney R. Miura, Y. Nishina, K. Sato, S. Fujii, K. Kuroda and K. Shiga Requires Authentication Unlicensed Licensed Download PDF	293
Resonance Raman Studies on Acyl-CoA Dehydrogenases Y. Nishina, K. Sato, I. Hazekawa, S. Fujii, K. Kuroda, R. Miura and K. Shiga Requires Authentication Unlicensed Licensed Download PDF	303
Two New Mechanism-Based Inhibitors of the Acyl-CoA Dehydrogenases J.G. Cummings and C. Thorpe Requires Authentication Unlicensed Licensed Download PDF	313
STÜDES OF THE THERMODYNAMIC REGULATION OF MEDIUM CHAIN ACYL-CoA DEHYDROGENASE Bruce D. Johnson and Marian T. Stankovich Requires Authentication Unlicensed Licensed Download PDF	323
LONG-CHAIN SPECIFIC ENZYME FROM MEDIUM-CHAIN ACYL-COA DEHYDROGENASE A. Nandy, P. Bross, F. Kräutle, I. Rasched and S. Ghisla Requires Authentication Unlicensed Licensed Download PDF	327
Glutaryl-CoA dehydrogenase from anaerobic, benzoate degrading Pseudomonas sp.: An FAD-dependent glutaconyl-CoA decarboxylase Ulrich Härtel and Wolfgang Buckel Requires Authentication Unlicensed Licensed Download PDF	331
CRYSTALLIZATION AND PRELIMINARY X-RAY DIFFRACTION STUDY OF THE BIFUNCTIONAL FLAVOENZYME 5-HYDROXYVALERYL-COA DEHYDRATASE/DEHYDROGENASE FROM CLOSTRIDIUM AMINOVALERICUM Ulrich Eikmanns, Wolfgang Buckel and Emil F. Pai Requires Authentication Unlicensed Licensed Download PDF	335
ESSENTIAL ARGININE RESIDUE(S) OF 3-KETOSTEROID-Δ¹- DEHYDROGENASE Michiaki Kadode, Hiroyuki Matsushita, Kenzi Suzuki and Eiji Itagaki Requires Authentication Unlicensed Licensed Download PDF	339
Flavodoxins and Nitrogen Fixation - Structure, Electrochemistry and Post-translational Modification by Coenzyme A R.N.F. Thorneley, G.A. Ashby, M.H. Drummond, R.R. Eady, D.L. Hughes, G. Ford, P.M. Harrison, A. Shaw, R.L. Robson, J. Kazlauskaite and H.A.O. Hill Requires Authentication Unlicensed Licensed Download PDF	343
REGULATION OF THE EXPRESSION OF FLAVODOXIN AND FERREDOXIN IN Anabaena PCC 7120 UNDER IRON AND NITROGEN LIMITING CONDITIONS P. Razquin, M.L. Peleato, C. Gomez-Moreno, M.F. Fillat, S. Schmitz and H. Böhme Requires Authentication Unlicensed Licensed Download PDF	355
Crystallization and X-ray Structure Determination of E. coli Flavodoxin D. M. Hoover, R. G. Matthews and M. L. Ludwig Requires Authentication Unlicensed Licensed Download PDF	359
Cis-trans Isomerization of the 57-58 Peptide in Crystalline Flavodoxins from C. beijerinckii M.L. Ludwig, M.M. Dixon, K.A. Pattridge and R.P. Swenson Requires Authentication Unlicensed Licensed Download PDF	363
Electron-Transferring Flavoprotein from Pig Kidney Contains an AMP Kyosuke Sato, Yasuzo Nishina and Kiyoshi Shiga Requires Authentication Unlicensed Licensed Download PDF	367
The Enigma of Old Yellow Enzyme. II Vincent Massey Requires Authentication Unlicensed Licensed Download PDF	371
STIRRING NEW INTEREST IN AN OLD ENZYME: CRYSTAL STRUCTURE OF OLD YELLOW ENZYME Kristin M. Fox and P. Andrew Karplus Requires Authentication Unlicensed Licensed Download PDF	381
EFFECT OF DELETION AND MUTATION OF OLD YELLOW ENZYME GENE FROM SACCHAROMYCES CEREVISIAE Bette Jo Brown and Vincent Massey Requires Authentication Unlicensed Licensed Download PDF	391
STRUCTURE AND FUNCTION OF NADH-CYTOCHROME b5 REDUCTASE IN RELATION TO HEREDITARY METHEMOGLOBINEMIA Toshitsugu Yubisui, Komei Shirabe and Masazumi Takeshita Requires Authentication Unlicensed Licensed Download PDF	395
ROLE OF FLAVIN BINDING MOTIF, RxY(T/S), OF NADH-CYTOCHROME b₅ REDUCTASE IN ELECTRON TRANSFER REACTION Komei Shirabe, Toshitsugu Yubisui and Masazumi Takeshita Requires Authentication Unlicensed Licensed Download PDF	405
THE STRUCTURE OF HUMAN ERYTHROCYTE NADH-CYTOCHROME b₅ REDUCTASE AT 2.5Â RESOLUTION T. Takano, S. Bando, C. Horii, M. Higashiyama, K. Ogawa, M. Sato, Y. Katsuya, M. Danno, T. Yubisui, K. Shirabe and M. Takeshita Requires Authentication Unlicensed Licensed Download PDF	409
Two Bound Forms of Ferredoxin-NADP Reductase in Chloroplast Thylakoids Masateru Shin, Toyohiro Nishikawa, Toshihiro Sekido and Naoko Sakihama Requires Authentication Unlicensed Licensed Download PDF	413
CHARACTERIZATION OF ACTIVE-SITE MUTANTS OF FERREDOXIN-NADP⁺ REDUCTASE A. Aliverti, L. Piubelli, B. Curti and G. Zanetti Requires Authentication Unlicensed Licensed Download PDF	423
Structural Study of Ferredoxin-NADP⁺ Reductase from Anabaena PCC 7119 and of Its Complex with NADP⁺ L. Serre, F. Vellieux, J. Fontecilla-Camps, M. Frey, M. Medina and C. Gomez-Moreno Requires Authentication Unlicensed Licensed Download PDF	431
Structure-Function Relationships in Ferredoxin: Site-Directed Mutagenesis and Time-Resolved Absorption Spectroscopy Applied to the Ferredoxin:Ferredoxin NADP⁺ Reductase Interaction J.K. Hurley, Z. Salamon, T.E. Meyer, J.C. Fitch, M.A. Cusanovich, G. Tollin, H. Cheng, B. Xia, Y.K. Chae, J.L. Markley, M. Medina and C. Gomez-Moreno Requires Authentication Unlicensed Licensed Download PDF	435
N-Terminal Structure of Mature Ferredoxin-NADP Reductase Naoko Sakihama, Masateru Shin and Shigehiro Obata Requires Authentication Unlicensed Licensed Download PDF	439
Refined Crystal Structures of Native, Complexed and Reduced Forms of Spinach Ferredoxin Reductase C.M. Bruns and P.A. Karplus Requires Authentication Unlicensed Licensed Download PDF	443
Overexpression of ferredoxin-NADP⁺ reductase from Anabaena sp. PCC7119 in E.coli M.F. Fillat, M.C. Pacheco, M.L. Peleato and C. Gomez-Moreno Requires Authentication Unlicensed Licensed Download PDF	447
THE REDUCTASE ACTIVITY OP A FLAVOPROTEIN IS CHANGED INTO A SUPEROXIDE-FORMING OXIDASE BY CHEMICAL MODIFICATION M.T. Bes, M.L. Peleato, C. Gómez-Moreno, A. López and V.M. Fernández Requires Authentication Unlicensed Licensed Download PDF	451
FNR -LIKE FLAVOPROTEINS OF CHEMOAUTOTROPHIC BACTERIA AND PHOTOSYNTHETIC BACTERIA Y. Fukumori, S. Hikichi and T. Yamanaka Requires Authentication Unlicensed Licensed Download PDF	455
¹H NMR investigation of NADPH-adrenoferredoxin reductase with NADP⁺ and adrenoferredoxin Shigetoshi Miura and Yoshiyuki Ichikawa Requires Authentication Unlicensed Licensed Download PDF	459
One electron reduction of adrenodoxin reductase as studied by pulse radiolysis M. Miki, K. Kobayashi, S. Miura and Y. Ichikawa Requires Authentication Unlicensed Licensed Download PDF	463
STRUCTURE-FUNCTION STUDIES ON NADPH-CYTOCHROME P450 REDUCTASE USING UREA-PERTURBATION AND ¹⁹F NMR SPECTROSCOPY R. Narayanasami, P. M. Horowitz, B. S. S. Masters and J. D. Otvos Requires Authentication Unlicensed Licensed Download PDF	467
Cerebellar Nitric Oxide Synthase Behaves as a Bi-Domain Structure Bettie Sue Siler Masters, Essam Sheta and Kirk McMillan Requires Authentication Unlicensed Licensed Download PDF	471
STUDIES ON NAD(P)H-QUINONE OXIDOREDUCTASE Gabriella Tedeschi, Shiuan Chen and Vincent Massey Requires Authentication Unlicensed Licensed Download PDF	475
EFFECT OF RIBOFLAVIN DEFICIENCY ON DT-DIAPHORASE K. Yagi, S. Komura, M. Nakashima, N. Ishida, N. Ohishi and L. Ernster Requires Authentication Unlicensed Licensed Download PDF	479
DISULFIDE REDUCTASES
Hybrid Molecules of Glutathione Reductase: Tools for Investigating Protein Interactions at the Dimer Interface Nigel S. Scrutton, Mahendra P. Deonarain, Alan Berry and Richard N. Peiham Requires Authentication Unlicensed Licensed Download PDF	485
THE REDUCTIVE HALF REACTION OF ESCHERICHIA COLI GLUTATHIONE REDUCTASE Patrick Rietveld, L. David Arscott and Charles H. Williams Requires Authentication Unlicensed Licensed Download PDF	493
DETERMINATION OF THE REDOX POTENTIAL OF E. COLI GLUTATHIONE REDUCTASE USING NADH AND NAD⁺ Donna M. Veine, L. David Arscott and Charles H. Williams Requires Authentication Unlicensed Licensed Download PDF	497
AN INVESTIGATION OF ENGINEERED CO-OPERATIVITY IN INTERFACE MUTANTS OF ESCHERICHIA COU GLUTATHIONE REDUCTASE Asam Bashir, Matthew J. Cockerill, Alan Berry, Nigel S. Scrutton and Richard N. Perham Requires Authentication Unlicensed Licensed Download PDF	501
ROLE OF CONSERVED GLYCINE RESIDUES IN THE NADPH BINDING MOTIF OF GLUTATHIONE REDUCTASE Maria Rescigno and Richard N. Perham Requires Authentication Unlicensed Licensed Download PDF	505
Eukaryotic Lipoamide Dehydrogenase: Molecular Genetic and Structural Aspects Kichiko Koike, Masahiko Koike and Akio Takenaka Requires Authentication Unlicensed Licensed Download PDF	509
Disruption of the Gene Coding for Dihydrolipoamide Dehydrogenase in Haloferax volcanii by Homologous Recombination N.N. Vettakkorumakankav, Kj. Stevenson, L. C. Schalkwyk and W. F. Doolittle Requires Authentication Unlicensed Licensed Download PDF	519
Redox Properties of the FAD in the Active Site Mutants C44S and C49S of Escherichia coli Lipoamide Dehydrogenase Nancy Hopkins and Charles H. Williams Requires Authentication Unlicensed Licensed Download PDF	523
R- AND S-DIHYDROLIPOIC ACID DERIVATIVES AS SUBSTRATES OF LIPO AMIDE DEHYDROGENASE L. David Arscott and Charles H. Williams Requires Authentication Unlicensed Licensed Download PDF	527
Comparative Study on Flavin Radical Formation of Llipoamide Dehydrogenase and Glutathione Reductase by Photoreduction Kazuko Maeda-Yorita and Kenji Aki Requires Authentication Unlicensed Licensed Download PDF	531
The Pyruvate Dehydrogenase Complex from Azotobacter vinelandii A. de Kok, A. Berg, W. van Berkel, A. Fabisz-Kijowska, A. Westphal, F. van den Akker, A. Mattevi and W.G.J. Hoi Requires Authentication Unlicensed Licensed Download PDF	535
The 3-dimensional structure of trypanothione reductase from Trypanosoma cruzi as a basis for drug design against Chagas' disease R.L. Krauth-Siegel, E. Jacoby and C.B. Lantwin Requires Authentication Unlicensed Licensed Download PDF	545
MECHANISM AND STRUCTURE OF THIOREDOXIN REDUCTASE Talluru S. R. Krishna, Gabriel Waksman, John Kuriyan, Scott B. Mulrooney, Brett W. Lennon and Charles H. Williams Requires Authentication Unlicensed Licensed Download PDF	557
E. COLI THIOREDOXIN REDUCTASE - POTENTIAL ACID-BASE CATALYSTS - PROPERTIES OF HIS-245 AND ASP-139 MUTANTS Scott B. Mulrooney, Aileen Nicoletti, Jirundon Yuvaniyama and Charles H. Williams Requires Authentication Unlicensed Licensed Download PDF	567
RAPID REACTION KINETICS OF ESCHERICHIA COLI THIOREDOXIN REDUCTASE Brett W. Lennon and Charles H. Williams Requires Authentication Unlicensed Licensed Download PDF	571
2'- Fluoro - 2'- Deoxy - Arabino - FAD: Effects On The Formation And Stability Of 2-Electron Reduced Mercuric Ion Reductase S.M. Miller Requires Authentication Unlicensed Licensed Download PDF	575
The Alkyl Hydroperoxide Reductase of Salmonella typhimurium: Redox Activity of the Cystine Disulfide of AhpC and Evidence for Involvement in Peroxide Reduction Leslie B. Poole Requires Authentication Unlicensed Licensed Download PDF	583
FLAVOPROTEIN PEROXIDE AND DISULFIDE REDUCTASES AND THEIR ROLES IN STREPTOCOCCAL OXIDATIVE METABOLISM Al Claiborne, R. Paul Ross, Don Ward, Derek Parsonage and Edward J. Crane Requires Authentication Unlicensed Licensed Download PDF	587
N⁶-(2-AMINOETHYL)-FAD: SYNTHESIS AND COENZYME ACTIVITY WITH RESPECT TO APO-NADH OXIDASE FROM THERMUS THERMOPHILICS AND THERMUS AQUATICUS A. F. Bückmann, H. Erdmann, M. Pietzsch, J. M. Hall and J. V. Bannister Requires Authentication Unlicensed Licensed Download PDF	597
A FLAVOPROTEIN FUNCTIONAL AS NADH OXIDASE FROM Amphibacillus xylanus EpOl Youichi Niimura, Kenji Ohnishi, Kazunori Yokoyama and Takeshi Nishino Requires Authentication Unlicensed Licensed Download PDF	601
COMPLEX FLAVOPROTEINS
Probing the Structure and Function of Flavocytochrome b² Using Protein Engineering Methods Stephen K. Chapman, Patricia White, Simon Daff, Graeme A. Reid, R. Eryl Sharp and Forbes D.C. Manson Requires Authentication Unlicensed Licensed Download PDF	607
The L-Mandelate Dehydrogenase from Rhodotorula gratninis is a Flavocytochrome b₂ Stephen K. Chapman, Otto Smekal and Graeme A. Reid Requires Authentication Unlicensed Licensed Download PDF	617
S-MANDEL ATE DEHYDROGENASE FROM PSEUDOMONAS PUTIDA: CONSTRUCTION OF A SOLUBLE CHIMERIC MUTANT OF A MEMBRANE-BOUND ENZYME Bharati Mitra, John A. Gerlt, Patricia C. Babbitt, George L. Kenyon, Diane Joseph and Gregory A. Petsko Requires Authentication Unlicensed Licensed Download PDF	621
The D282N and Y254L active-site mutants of flavocytochrome b₂ are expressed in E. coli as a mixture of holoenzyme and flavin-free protein Muriel Gondry, Myriam Schaffner, Forbes D.C. Manson, Stephen K. Chapman, Graeme A. Reid and Florence Lederer Requires Authentication Unlicensed Licensed Download PDF	625
RECONSTITUTION OF FLAVIN-FREE FLAVOCYTOCHROME b₂ WITH 5-DEAZAFMN : A CARBANION OR A HYDRIDE MECHANISM ? Alexis Balme and Florence Lederer Requires Authentication Unlicensed Licensed Download PDF	629
Physical Studies on Phthalate Dioxygenase Reductase (PDR) D. Ballou, G. Gassner, L. Wang, C. Batie, D. Gatti, W. R. Dunham and R.H. Sands Requires Authentication Unlicensed Licensed Download PDF	639
Structures of Oxidized, Reduced, and Liganded States of the Iron-Sulfur Flavoprotein, Phthalate Dioxygenase Reductase C. C. Correll, D.L. Gatti and M.L. Ludwig Requires Authentication Unlicensed Licensed Download PDF	649
Flavin and iron-sulfur cluster containing hydroxyacyl-CoA dehydratases (I) (R)-2-Hydroxyglutaryl-CoA dehydratases from Acidaminococcus fermentans and Fusobacterium nucleatum U. Müller, A.-G. Klees, K. Bendrat, M. Mack and W. Buckel Requires Authentication Unlicensed Licensed Download PDF	659
Flavin and iron-sulfur containing hydroxyacyl-CoA dehydratases (II) 4-Hydroxybutyryl-CoA dehydratase from Clostridium aminobutyricum Uwe Scherf and Wolfgang Buckel Requires Authentication Unlicensed Licensed Download PDF	663
Glutamate synthase from AzospiriUum brasilense: structural and mechanistic studies Maria A. Vanoni Requires Authentication Unlicensed Licensed Download PDF	667
Cloning and Expression of Azospirillum brasilense Glutamate Synthase R. Pelanda, L. Piubelli, P. Fumagalli, A. Mazzoni, E. Verzotti, M A. Vanoni, G. Zanetti and B. Curti Requires Authentication Unlicensed Licensed Download PDF	675
Phototrophic Bacterial Flavocytochromes c M. A. Cusanovich, R. G. Bartsch, M. M. Dolata, J. Fitch, T. E. Meyer, E. Varga and J. Van Beeumen Requires Authentication Unlicensed Licensed Download PDF	685
Structure and Function of the Soluble Fumarate Reductase, Flavocytochrome c, from Shewanella putrefaciens Graeme A Reid, Sara L. Pealing, Forbes D. C. Manson, F. Bruce Ward and Stephen K. Chapman Requires Authentication Unlicensed Licensed Download PDF	695
XANTHINE DEHYDROGENASE: STRUCTURE AND PROPERTIES Takeshi Nishino, Tomoko Nishino, Akira Sato, Theodore Page and Yoshihiro Amaya Requires Authentication Unlicensed Licensed Download PDF	699
THE PRIMARY STRUCTURE OF HUMAN XANTHINE DEHYDROGENASE AND CHROMOSOMAL LOCATION OF THE GENE Kimiyoshi Ichida, Tatsuo Hosoya, Osamu Sakai, Shinsei Minoshima, Nobuyoshi Shimizu, Yoshihiro Amaya, Kumi Noda and Takeshi Nishino Requires Authentication Unlicensed Licensed Download PDF	707
Overexpression and Characterization of Xanthine Dehydrogenase in a Baculovirus-Insectcell System Tomoko Nishino, Tatsuya Saito, Yoshihiro Amaya, Susumu Kawamoto, Yoshiaki Ikemi and Takeshi Nishino Requires Authentication Unlicensed Licensed Download PDF	711
Redox Potentials of Milk Xanthine Dehydrogenase Jennifer Hunt and Vincent Massey Requires Authentication Unlicensed Licensed Download PDF	715
Electron transfer in milk xanthine dehydrogenase as studied by pulse radiolysis K. Kobayashi, M. Miki, K. Okamoto and T. Nishino Requires Authentication Unlicensed Licensed Download PDF	719
A COMPARISON OF SUBSTRATE SPECIFICITY BETWEEN MILK XANTHINE OXIDASE AND XANTHINE DEHYDROGENASE Christopher M. Harris and Vincent Massey Requires Authentication Unlicensed Licensed Download PDF	723
CRYSTALLIZATION AND PRELIMINARY X-RAY DIFFRACTION OF XANTHINE OXIDASE ISOLATED FROM BOVINE MILK B. T. Eger, U. Eikmanns, E. F. Pai, M. Sato, K. Okamoto and T. Nishino Requires Authentication Unlicensed Licensed Download PDF	727
NEW TIGHT BINDING INHIBITORS OF XANTHINE OXIDASE Ken Okamoto, Takeshi Iwamoto and Takeshi Nishino Requires Authentication Unlicensed Licensed Download PDF	731
Molecular cloning and structural characterization of the gene locus coding for mouse xanthine oxidoreductase G. Cazzaniga, E. Garattini, P. Lo Schiavo, F. Segalla, F. Galbiati and M. Terao Requires Authentication Unlicensed Licensed Download PDF	735
Mouse L929 cells are defective in the expression of xanthine oxidoreductase enzymatic activity and molybdenum (VI) salts can complement the deficit F. Falciani, M. Terao, S. Goldwurm, M. Li Calzi, M. Salmona, G. Cazzaniga, E. Garattini, A. Ronchi, A. Gatti and C. Minoia Requires Authentication Unlicensed Licensed Download PDF	739
Physicochemical Properties of Retinal Oxidase Purified from Rabbit Hepatic Cytosol Maki Tsujita, Shuhei Tomita, Yoshinori Matsuo, Shigetoshi Miura and Yoshiyuki Ichikawa Requires Authentication Unlicensed Licensed Download PDF	743
Mutagenesis of the Cysteine Residues of the FAD Domain of Nitrate Reductase Wilbur H. Campbell and U.N. Dwivedi Requires Authentication Unlicensed Licensed Download PDF	747
Electron Transfer and Prototropic Equilibria in Two Complex Metalloflavoproteins Russ Hille and Ronald J. Rohlfs Requires Authentication Unlicensed Licensed Download PDF	751
THE ABSENCE OF PROTOHEME IN ACTIVE RESPIRATORY COMPLEX II OF THE THERMO ACIDOPHILIC ARCH AEON, SULFOLOBUS SP. STRAIN 7 Toshio Iwasaki, Takayoshi Wakagi, Tairo Oshima and Katsumi Matsuura Requires Authentication Unlicensed Licensed Download PDF	755
Unique Properties of the "Rotenone Site" of NADH-Q Oxidoreductase Thomas P. Singer and Rona R. Ramsay Requires Authentication Unlicensed Licensed Download PDF	759
Reconstitution of a Cell-free Superoxide Generation of Human Neutrophil Y. Nisimoto and H.O. Murakami Requires Authentication Unlicensed Licensed Download PDF	763
FLAVOPROTEINS CONTAINING COVALENTLY-BOUND FLAVINS
Preparation and Properties of Recombinant Corynebacterial Sarcosine Oxidase Lawrence J. Chlumsky, Lening Zhang and Marilyn S. Jorns Requires Authentication Unlicensed Licensed Download PDF	769
One-Step Cloning and Overexpression of the Sarcosine Oxidase Operon from Corynebacterium sp. P-1 Lawrence J. Chlumsky, Andrew J. Ramsey and Marilyn S. Jorns Requires Authentication Unlicensed Licensed Download PDF	779
L-GULONO-γ-LACTONE OXIDASE — cDNA CLONING AND ELUCIDATION OF THE GENETIC DEFECT IN A MUTANT RAT WITH OSTEOGENIC DISORDER K. Yagi and M. Nishikimi Requires Authentication Unlicensed Licensed Download PDF	783
HIGH-LEVEL EXPRESSION OF RAT L-GULONO-y-LACTONE OXIDASE IN SILKWORM CELLS WITH A BACULOVIRUS VECTOR M. Nishikimi, K. Yagi and J. Kobayashi Requires Authentication Unlicensed Licensed Download PDF	791
Structures Responsible for FAD Binding and Substrate Recognition of Rat Liver Monoamine Oxidase F. Ogata, Y. Tsugeno, I. Hirasiki, J. Mitoma and A. Ito Requires Authentication Unlicensed Licensed Download PDF	795
Vanillyl-Alcohol Oxidase from Pénicillium simplicissimum: A Novel Flavoprotein Containing 8a-(N³-histidyl)-FAD W.J.H. van Berkel, M.W. Fraaije, E. de Jong and J.A.M. de Bont Requires Authentication Unlicensed Licensed Download PDF	799
Flavinylation of the Trimethylamine Dehydrogenase of Bacterium W₃A₁ Expressed in Escherichia coli Nigel S. Scrutton, Leonard C. Packman and F. Scott Mathews Requires Authentication Unlicensed Licensed Download PDF	803
A New Family of Flavoenzymes ? R. Brandsch Requires Authentication Unlicensed Licensed Download PDF	807
ENZYMES USING REDUCED FLAVIN FOR THEIR ACTIVITY
THE BACTERIAL LUCIFERASE REACTION: MODEL OR MAVERICK IN FLAVIN BIOCHEMISTRY? J. Woodland Hastings Requires Authentication Unlicensed Licensed Download PDF	813
KINETIC CONTROL OF FOLDING AND ASSEMBLY OF HETERODIMERIC BACTERIAL LUCIFERASE T. O. Baldwin, M. M. Ziegler, J. F. Sinclair, A. C. Clark and A.-F. Chaffotte Requires Authentication Unlicensed Licensed Download PDF	823
KINETIC MECHANISM OF THE BACTERIAL LUCIFERASE REACTION W. A. Francisco, H. M. Abu-Soud, A. C. Clark, F. M. Raushel and T. O. Baldwin Requires Authentication Unlicensed Licensed Download PDF	829
BACTERIAL LUCIFERASE: BIOLUMINESCENCE EMISSION USING LUMAZINES AS SUBSTRATES Peter Macheroux, Sandro Ghisla and J. Woodland Hastings Requires Authentication Unlicensed Licensed Download PDF	839
Studies on Escherichia coli Chorismate Synthase S. Bornemann, M. N. Ramjee, D. J. Lowe, R. N. F. Thorneley, J. R. Coggins, C. Abell, S. Balasubramanian, T. R. Hawkes, W. W. Nichols and G. M. Davies Requires Authentication Unlicensed Licensed Download PDF	843
Characterization of the Vibrio harveyi NADPH:FMN Oxidoreductase Expressed in Escherichia coli Benfang Lei and Shiao-Chun Tu Requires Authentication Unlicensed Licensed Download PDF	847
LIST OF PARTICIPANTS Requires Authentication Unlicensed Licensed Download PDF	851
AUTHOR INDEX Requires Authentication Unlicensed Licensed Download PDF	857
SUBJECT INDEX Requires Authentication Unlicensed Licensed Download PDF	865
Backmatter Requires Authentication Unlicensed Licensed Download PDF	891

Language: English
Publisher: De Gruyter
Edition: Reprint 2020
Pages
- Front matter: 20
- Main content: 889
Illustrations
- Illustrations: 392
- Tables: 91
Keywords: Flavine; Flavoenzym

eBook

Published: October 12, 2020
ISBN: 9783110885774

Hardcover

Published: September 1, 1994
ISBN: 9783110141658