ABSTRACT

This is the first comprehensive text to provide not only a detailed explanation of how the SARS-CoV2 (COVID-19) virus is spread within human populations, but also an epidemiological analysis and interpretation of viral pandemics to enable better measures for prevention and control.

Providing an introduction to the physiology of both the human immune system and the SARS-CoV2 virus, specifically the virus’s replicative potential and our own vulnerability, the book offers an in-depth understanding of how the pandemic evolved. It also highlights the aberrant epigenomic mechanistic process in pathogenic microbe’s replication and survival, implying gene and environment interaction that affected different populations. Citing a range of environmental conditions, from structural and systemic racism to malnutrition and low-socioeconomic status, the book examines how these factors exacerbated existing health disparities, resulting in a disproportionate burden of morbidity and mortality on certain social groups.

Also providing invaluable guidance on how future iterations of this pandemic may be better prevented and controlled, this will be a defining book for students, researchers and professionals within Public Health and Clinical Medicine to better understand the SARS-CoV2 (COVID-19) virus, and how to protect the most vulnerable social groups.

chapter 1|8 pages

Immuno-Epidemiologic Perspective in Pathogenic Microbes

Immune System Response and Integration

chapter 2|13 pages

Immuno-Epidemiologic Perspective in Pathogenic Microbes

Epidemiologic Principles and Concepts

chapter 3|4 pages

SARS-CoV2 (COVID-19)

Pandemic and Public Health Emergency Response

chapter 4|3 pages

SARS-CoV2 Mutation

Immuno-Epidemiologic and Socio-Epidemiologic Response

chapter 5|3 pages

COVID-19 Pandemic

Epidemic Curve Down-Drifting and Case Fatality Mitigation

chapter 6|3 pages

Pregnancy Risk in SARS-CoV2 Transmission and COVID-19 Fetal Survivability

Immuno-Epidemiologic Perspective

chapter 8|3 pages

Social Injustice and Systemic Racism

Obstacles to COVID-19 Pandemic Global Health Equity Transformation

chapter 9|3 pages

SARS-CoV2 “Re-emergence” as COVID-19 (2)

Translational Public Health and Immuno-Epidemiologic Response

chapter 12|7 pages

SARS-CoV2 Exponential Spread and COVID-19 Hospitalization, Case Fatality and Mortality

US Pandemic Mitigation and Stabilization Measures Regression

chapter 13|4 pages

SARS-CoV2 (COVID-19) Synergistic Spread

Conjoint Effect of Personal Responsibility, Control/Preventive Measures and Vaccine Effectiveness

chapter 14|5 pages

SARS-CoV2 Vaccine versus Vaccination

Immunologic Durability and Community Disproportionate Benefit in the United States and Globally

chapter 15|3 pages

“COVIDMAS”​ and SARS-CoV2 (COVID-19) Pandemic Attenuation

Emerging New Strain (Antigenic Subtypes) and Subpopulations Obstacles to Vaccination

chapter 17|4 pages

SARS-CoV2 (COVID-19) Disproportionate Burden

Hypertension and Mental Health among US Racial/Ethnic Minorities – Blacks/African Americans (AA)

chapter 21|4 pages

SARS-CoV2 Omicron Variant

Transmissibility, Clinical Manifestations, Severity and Vaccine Effectiveness

chapter 24|3 pages

Ukraine Invasion and Global SARS-CoV2 (COVID-19) Pandemic Resurgence

Epigenomic Public Health Perspective

chapter 25|7 pages

SARS-CoV2 (COVID-19) Global Pandemic

“Extreme Epidemiology” Response in Transmission and Case Fatality Stabilization, Mitigation and Control